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ONTOLOGY REPORT - ANNOTATIONS

Term:dedifferentiation
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Accession:GO:0043696 term browser browse the term
Definition:The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.
Synonyms:xref: Wikipedia:Cellular_differentiation#Dedifferentiation


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cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk6 cyclin-dependent kinase 6 involved_in ISO (PMID:12861051) RGD PMID:12861051 NCBI chr 4:30,637,650...30,829,688
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Esrrb estrogen-related receptor beta involved_in ISS
ISO		 GO_REF:0000024
(MGI:5882870|PMID:23040477)		 UniProt
RGD		 PMID:23040477 GO_REF:0000024 MGI:5882870 NCBI chr 6:106,007,701...106,163,136
Ensembl chr 6:106,008,095...106,160,791 		JBrowse link
G Fezf1 Fez family zinc finger 1 involved_in ISO UniProtKB:Q9VQ56 (MGI:5905549|PMID:20152183) RGD PMID:20152183 MGI:5905549 NCBI chr 4:51,762,751...51,766,078
Ensembl chr 4:51,762,751...51,766,078 		JBrowse link
G Fezf2 Fez family zinc finger 2 involved_in ISO UniProtKB:Q9VQ56 (MGI:5905549|PMID:20152183) RGD PMID:20152183 MGI:5905549 NCBI chr15:12,768,614...12,777,554
Ensembl chr15:12,773,762...12,777,554 		JBrowse link
G Nanog Nanog homeobox involved_in ISO (MGI:5882870|PMID:23040477) RGD PMID:23040477 MGI:5882870 NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5440110|PMID:23019124)		 UniProt
RGD		 PMID:23019124 GO_REF:0000024 MGI:5440110 NCBI chr 3:154,738,566...154,821,395
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
hepatocyte dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpd heterogeneous nuclear ribonucleoprotein D IEP RGD PMID:20102719 RGD:10042969 NCBI chr14:9,615,375...9,638,975
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
positive regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir214 microRNA 214 involved_in ISO (PMID:27144530) RGD PMID:27144530 NCBI chr13:74,588,374...74,588,481
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:19088079) RGD PMID:19088079 NCBI chr  X:3,429,465...3,429,573
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
IEA		 (PMID:19088079)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088079 GO_REF:0000107 NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Olfm2 olfactomedin 2 involved_in IMP PMID:28062493 UniProt PMID:28062493 RGD:13441204 NCBI chr 8:19,204,472...19,282,154
Ensembl chr 8:19,204,475...19,282,117 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20413
    developmental process 7068
      dedifferentiation 11
        cell dedifferentiation + 11
paths to the root