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ONTOLOGY REPORT - ANNOTATIONS

Term:dedifferentiation
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Accession:GO:0043696 term browser browse the term
Definition:The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.
Synonyms:xref: Wikipedia:Cellular_differentiation#Dedifferentiation


show annotations for term's descendants           Sort by:
cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdk6 cyclin-dependent kinase 6 involved_in ISO
IEA		 (PMID:12861051)
GO_REF:0000107
GO_REF:0000002		 RGD
Ensembl
InterPro		 PMID:12861051 GO_REF:0000002 GO_REF:0000107 NCBI chr 4:31,592,384...31,784,732
Ensembl chr 4:30,646,460...30,829,634 		JBrowse link
G Esrrb estrogen-related receptor beta involved_in ISS
ISO		 GO_REF:0000024
(PMID:23040477)		 UniProt
RGD		 PMID:23040477 GO_REF:0000024 NCBI chr 6:111,738,662...111,894,087
Ensembl chr 6:106,008,095...106,160,791 		JBrowse link
G Fezf1 Fez family zinc finger 1 involved_in ISO
IEA		 UniProtKB:Q9VQ56 (PMID:20152183)
GO_REF:0000107		 RGD
Ensembl		 PMID:20152183 GO_REF:0000107 NCBI chr 4:52,728,385...52,733,315
Ensembl chr 4:51,762,751...51,766,078 		JBrowse link
G Fezf2 Fez family zinc finger 2 involved_in ISO
IEA		 UniProtKB:Q9VQ56 (PMID:20152183)
GO_REF:0000107		 RGD
Ensembl		 PMID:20152183 GO_REF:0000107 NCBI chr15:15,199,045...15,207,982
Ensembl chr15:12,773,762...12,777,554 		JBrowse link
G Nanog Nanog homeobox involved_in ISO
IEA		 (PMID:23040477)
GO_REF:0000107		 RGD
Ensembl		 PMID:23040477 GO_REF:0000107 NCBI chr 4:157,615,687...157,623,061
Ensembl chr 4:155,943,737...155,951,116 		JBrowse link
G Ncoa3 nuclear receptor coactivator 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:23019124)		 UniProt
RGD		 PMID:23019124 GO_REF:0000024 NCBI chr 3:175,157,824...175,237,831
Ensembl chr 3:154,738,581...154,818,594 		JBrowse link
hepatocyte dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnrnpd heterogeneous nuclear ribonucleoprotein D IEP RGD PMID:20102719 RGD:10042969 NCBI chr14:9,918,630...9,938,072
Ensembl chr14:9,615,479...9,633,786 		JBrowse link
negative regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir182 microRNA 182 involved_in ISO (PMID:28259995) RGD PMID:28259995 NCBI chr 4:59,752,246...59,752,307
Ensembl chr 4:58,784,818...58,784,879 		JBrowse link
positive regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mir214 microRNA 214 involved_in ISO (PMID:27144530) RGD PMID:27144530 NCBI chr13:77,121,645...77,121,752
Ensembl chr13:74,588,372...74,588,481 		JBrowse link
G Mir221 microRNA 221 involved_in ISO (PMID:19088079) RGD PMID:19088079 NCBI chr  X:6,023,182...6,023,290
Ensembl chr  X:3,429,465...3,429,573 		JBrowse link
G Pdgfb platelet derived growth factor subunit B involved_in ISO
IEA		 (PMID:19088079)
GO_REF:0000107		 RGD
Ensembl		 PMID:19088079 GO_REF:0000107 NCBI chr 7:113,419,882...113,438,343
Ensembl chr 7:111,540,345...111,557,984 		JBrowse link
regulation of vascular associated smooth muscle cell dedifferentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Olfm2 olfactomedin 2 involved_in IMP PMID:28062493 UniProt PMID:28062493 RGD:13441204 NCBI chr 8:27,480,703...27,558,416
Ensembl chr 8:19,204,475...19,282,117 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20558
    developmental process 7149
      dedifferentiation 12
        cell dedifferentiation + 12
paths to the root