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ONTOLOGY REPORT - ANNOTATIONS

Term:engulfment of apoptotic cell
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Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse

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engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Becn1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936490:17,518,100...17,531,126
Ensembl chrNW_004936490:17,517,751...17,531,151 		JBrowse link
G LOC101964702 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936470:9,247,749...9,313,230
Ensembl chrNW_004936470:9,248,319...9,313,230 		JBrowse link
G Megf10 multiple EGF like domains 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27170117) Ensembl
MGI		 PMID:27170117 GO_REF:0000107 NCBI chrNW_004936504:634,167...753,438
Ensembl chrNW_004936504:586,190...756,255 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936750:107,689...122,679
Ensembl chrNW_004936750:107,689...122,676 		JBrowse link
G Rac2 Rac family small GTPase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936492:3,726,375...3,737,961
Ensembl chrNW_004936492:3,726,313...3,736,905 		JBrowse link
G Rac3 Rac family small GTPase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936594:5,527,788...5,530,694
Ensembl chrNW_004936594:5,528,908...5,531,420 		JBrowse link
G Rhobtb1 Rho related BTB domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936614:2,101,175...2,230,441
Ensembl chrNW_004936614:2,103,101...2,230,444 		JBrowse link
G Rhobtb2 Rho related BTB domain containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936555:6,664,811...6,684,756
Ensembl chrNW_004936555:6,664,768...6,682,822 		JBrowse link
G Rhog ras homolog family member G involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936498:1,077,354...1,088,003
Ensembl chrNW_004936498:1,077,422...1,088,003 		JBrowse link
G Rhoh ras homolog family member H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936482:7,721,815...7,723,395
Ensembl chrNW_004936482:7,689,371...7,723,321 		JBrowse link
G Thbs1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936471:3,064,466...3,081,125
Ensembl chrNW_004936471:3,064,422...3,081,949 		JBrowse link
G Xkr4 XK related 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936496:1,887,943...2,289,928
Ensembl chrNW_004936496:1,888,068...2,287,963 		JBrowse link
G Xkr5 XK related 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936615:4,734,805...4,753,194
Ensembl chrNW_004936615:4,734,805...4,753,194 		JBrowse link
G Xkr6 XK related 6 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936675:2,750,401...2,768,457
Ensembl chrNW_004936675:2,751,400...2,983,960 		JBrowse link
G Xkr7 XK related 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936485:18,907,218...18,935,306
Ensembl chrNW_004936485:18,907,218...18,929,904 		JBrowse link
G Xkr8 XK related 8 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004936474:12,180,741...12,187,904
Ensembl chrNW_004936474:12,180,424...12,187,876 		JBrowse link
G Xkr9 XK related 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004936648:1,607...5,784
Ensembl chrNW_004936648:1,573...5,784 		JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:3662940|PMID:16908670)
(PMID:16908670)		 Alzheimers_University_of_Toronto PMID:16908670 MGI:3662940 NCBI chrNW_004936588:460,308...477,382
Ensembl chrNW_004936588:461,389...477,229 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936476:18,659,725...18,665,406
Ensembl chrNW_004936476:18,659,815...18,663,940 		JBrowse link
regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936677:3,232,183...3,241,307
Ensembl chrNW_004936677:3,232,183...3,241,253 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16133
    cellular process 15768
      vesicle-mediated transport 1536
        endocytosis 683
          phagocytosis 216
            apoptotic cell clearance 48
              engulfment of apoptotic cell 20
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 3
Path 2
Term Annotations click to browse term
  biological_process 16133
    localization 5232
      establishment of localization 4544
        transport 4255
          vesicle-mediated transport 1536
            endocytosis 683
              phagocytosis 216
                phagocytosis, engulfment 59
                  engulfment of apoptotic cell 20
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 3
paths to the root