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ONTOLOGY REPORT - ANNOTATIONS

Term:engulfment of apoptotic cell
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Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse


show annotations for term's descendants           Sort by:
engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in ISO
IBA
IEA		 (PMID:24509909)
GO_REF:0000033
GO_REF:0000107
(MGI:3764740|PMID:17960134)		 RGD
GO_Central
Ensembl		 PMID:17960134 PMID:24509909 GO_REF:0000033 GO_REF:0000107 MGI:3764740 NCBI chr 7:106,404,827...106,476,902
Ensembl chr 7:106,404,958...106,476,902 		JBrowse link
G Becn1 beclin 1 involved_in ISO (MGI:5619450|PMID:22393062) RGD PMID:22393062 MGI:5619450 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Megf10 multiple EGF-like domains 10 acts_upstream_of_or_within ISO MGI:4454190 (PMID:27170117) RGD PMID:27170117 NCBI chr18:50,605,231...50,755,441
Ensembl chr18:50,605,656...50,754,456 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in ISO
IBA		 (MGI:4943793|PMID:20691665)
GO_REF:0000033		 RGD
GO_Central		 PMID:20691665 GO_REF:0000033 MGI:4943793 NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251 		JBrowse link
G Rac3 Rac family small GTPase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr10:106,002,808...106,005,243
Ensembl chr10:105,993,087...106,005,260 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:16882710) RGD PMID:16882710 NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Xkr4 XK related 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:15,896,818...16,297,733
Ensembl chr 5:15,895,863...16,282,962 		JBrowse link
G Xkr6 XK related 6 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr15:37,857,096...38,059,699
Ensembl chr15:37,857,096...38,059,682 		JBrowse link
G Xkr7 XK related 7 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:141,500,908...141,525,062
Ensembl chr 3:141,501,284...141,525,062 		JBrowse link
G Xkr8 XK related 8 involved_in ISO
IBA		 (PMID:23845944)
(PMID:29440417), (PMID:31712393)
GO_REF:0000033
(MGI:6120635|PMID:29440417), (MGI:6435898|PMID:31712393)		 RGD
GO_Central		 PMID:23845944 PMID:29440417 PMID:31712393 GO_REF:0000033 MGI:6120635 MGI:6435898 NCBI chr 5:144,938,061...144,945,195
Ensembl chr 5:144,938,064...144,945,195 		JBrowse link
G Xkr9 XK related 9 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:5,530,384...5,562,168
Ensembl chr 5:5,533,416...5,562,168 		JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3662940|PMID:16908670)
(PMID:16908670)		 Alzheimers_University_of_Toronto
RGD		 PMID:16908670 GO_REF:0000024 MGI:3662940 NCBI chr 7:9,691,452...9,711,466
Ensembl chr 7:9,691,449...9,711,425 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:24990881) RGD PMID:24990881 NCBI chr 9:12,647,605...12,654,190
Ensembl chr 9:12,647,259...12,654,170 		JBrowse link
regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5436199|PMID:22503541), (MGI:5508294|PMID:11278875)
GO_REF:0000107
(PMID:11278875), (PMID:22503541)		 UniProt
RGD
Ensembl		 PMID:11278875 PMID:22503541 GO_REF:0000024 GO_REF:0000107 MGI:5436199 MGI:5508294 NCBI chr10:55,060,169...55,068,885
Ensembl chr10:55,060,412...55,068,874 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    cellular process 19325
      vesicle-mediated transport 1638
        endocytosis 735
          phagocytosis 234
            apoptotic cell clearance 45
              engulfment of apoptotic cell 14
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 3
Path 2
Term Annotations click to browse term
  biological_process 20133
    localization 5688
      establishment of localization 4991
        transport 4684
          vesicle-mediated transport 1638
            endocytosis 735
              phagocytosis 234
                phagocytosis, engulfment 62
                  engulfment of apoptotic cell 14
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 3
paths to the root