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ONTOLOGY REPORT - ANNOTATIONS

Term:engulfment of apoptotic cell
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Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse

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engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624735:14,049,621...14,126,287
Ensembl chrNW_004624735:14,050,213...14,113,534 		JBrowse link
G Becn1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004624795:1,386,154...1,406,314
Ensembl chrNW_004624795:1,385,756...1,405,714 		JBrowse link
G Megf10 multiple EGF like domains 10 acts_upstream_of_or_within ISO (PMID:27170117) MGI PMID:27170117 NCBI chrNW_004624774:14,147,412...14,354,886
Ensembl chrNW_004624774:14,153,687...14,355,406 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624740:30,912,841...30,933,882
Ensembl chrNW_004624740:30,911,598...30,934,025 		JBrowse link
G Rac2 Rac family small GTPase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624752:10,589,017...10,620,652
Ensembl chrNW_004624752:10,589,017...10,601,661 		JBrowse link
G Rac3 Rac family small GTPase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624801:10,862,490...10,864,856
Ensembl chrNW_004624801:10,862,502...10,864,879 		JBrowse link
G Rhobtb1 Rho related BTB domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624791:2,695,173...2,824,581
Ensembl chrNW_004624791:2,747,931...2,827,614 		JBrowse link
G Rhobtb2 Rho related BTB domain containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624758:18,444,684...18,463,988
Ensembl chrNW_004624758:18,444,608...18,464,071 		JBrowse link
G Rhog ras homolog family member G involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624817:5,269,691...5,281,160
Ensembl chrNW_004624817:5,269,691...5,281,101 		JBrowse link
G Rhoh ras homolog family member H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624761:26,717,857...26,721,628
Ensembl chrNW_004624761:26,720,478...26,721,053 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO (PMID:16882710) BHF-UCL PMID:16882710 NCBI chrNW_004624804:6,849,660...6,866,164
Ensembl chrNW_004624804:6,849,670...6,867,684 		JBrowse link
G Xkr7 XK related 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chrNW_004624741:531,924...561,198
Ensembl chrNW_004624741:537,263...561,198 		JBrowse link
G Xkr8 XK related 8 involved_in IEA TreeGrafter
Ensembl		 GO_REF:0000107 GO_REF:0000118 NCBI chrNW_004624764:11,809,146...11,816,878
Ensembl chrNW_004624764:11,809,176...11,816,960 		JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:3662940|PMID:16908670)
(PMID:16908670)		 Alzheimers_University_of_Toronto PMID:16908670 MGI:3662940 NCBI chrNW_004624828:7,572,821...7,592,428
Ensembl chrNW_004624828:7,573,130...7,591,038 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO (PMID:24990881) UniProt PMID:24990881 NCBI chrNW_004624754:17,643,397...17,649,255
Ensembl chrNW_004624754:17,643,363...17,648,231 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15248
    cellular process 14879
      vesicle-mediated transport 1463
        endocytosis 642
          phagocytosis 205
            apoptotic cell clearance 42
              engulfment of apoptotic cell 15
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 2
Path 2
Term Annotations click to browse term
  biological_process 15248
    localization 5016
      establishment of localization 4356
        transport 4075
          vesicle-mediated transport 1463
            endocytosis 642
              phagocytosis 205
                phagocytosis, engulfment 54
                  engulfment of apoptotic cell 15
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 2
paths to the root