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ONTOLOGY REPORT - ANNOTATIONS

Term:engulfment of apoptotic cell
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Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse


show annotations for term's descendants           Sort by:
engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrb1 adhesion G protein-coupled receptor B1 involved_in IDA
ISO
IBA		 (MGI:3764740|PMID:17960134)
(PMID:17960134)		 UniProt
GO_Central
MGI		 PMID:17960134 GO_REF:0000033 GO_REF:0000119 MGI:3764740 MGI:4834177 NCBI chr15:74,388,045...74,461,314
Ensembl chr15:74,388,044...74,461,314 		JBrowse link
G Becn1 beclin 1, autophagy related involved_in IMP (MGI:5619450|PMID:22393062) CACAO PMID:22393062 MGI:5619450 NCBI chr11:101,179,084...101,193,112
Ensembl chr11:101,176,778...101,193,112 		JBrowse link
G Megf10 multiple EGF-like-domains 10 acts_upstream_of_or_within IMP (PMID:27170117) MGI PMID:27170117 NCBI chr18:57,266,162...57,430,539
Ensembl chr18:57,266,162...57,430,539 		JBrowse link
G Rac1 Rac family small GTPase 1 involved_in IDA
IBA		 (MGI:4943793|PMID:20691665)
(PMID:20691665)		 BHF-UCL
GO_Central		 PMID:20691665 GO_REF:0000033 MGI:4943793 NCBI chr 5:143,491,236...143,513,786
Ensembl chr 5:143,489,389...143,513,791 		JBrowse link
G Rac3 Rac family small GTPase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr11:120,612,294...120,614,795
Ensembl chr11:120,612,296...120,614,795 		JBrowse link
G Thbs1 thrombospondin 1 involved_in ISO MGI
GO_Central		 GO_REF:0000119 MGI:4834177 NCBI chr 2:117,942,357...117,957,614
Ensembl chr 2:117,942,357...117,957,614 		JBrowse link
G Xkr4 X-linked Kx blood group related 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:3,269,956...3,741,733
Ensembl chr 1:3,276,124...3,741,721 		JBrowse link
G Xkr5 X-linked Kx blood group related 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:18,974,172...19,001,126
Ensembl chr 8:18,982,745...19,000,991 		JBrowse link
G Xkr6 X-linked Kx blood group related 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr14:63,841,608...64,084,451
Ensembl chr14:63,843,952...64,058,258 		JBrowse link
G Xkr7 X-linked Kx blood group related 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:152,873,772...152,902,214
Ensembl chr 2:152,873,772...152,897,695 		JBrowse link
G Xkr8 X-linked Kx blood group related 8 involved_in IMP
ISO
ISS
IBA		 (MGI:6120635|PMID:29440417), (MGI:6435898|PMID:31712393)
(PMID:29440417), (PMID:31712393)		 UniProt
GO_Central
MGI		 PMID:29440417 PMID:31712393 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 MGI:4834177 MGI:6120635 MGI:6435898 NCBI chr 4:132,452,212...132,459,916
Ensembl chr 4:132,452,208...132,459,857 		JBrowse link
G Xkr9 X-linked Kx blood group related 9 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 1:13,738,962...13,772,454
Ensembl chr 1:13,738,995...13,771,947 		JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca7 ATP-binding cassette, sub-family A member 7 involved_in IMP (MGI:3662940|PMID:16908670)
(PMID:16908670)		 Alzheimers_University_of_Toronto PMID:16908670 MGI:3662940 NCBI chr10:79,832,328...79,851,406
Ensembl chr10:79,832,328...79,851,406 		JBrowse link
G Trem2 triggering receptor expressed on myeloid cells 2 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr17:48,653,429...48,659,304
Ensembl chr17:48,653,429...48,661,175 		JBrowse link
regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alox15 arachidonate 15-lipoxygenase involved_in IMP (MGI:5436199|PMID:22503541), (MGI:5508294|PMID:11278875) UniProt PMID:11278875 PMID:22503541 MGI:5436199 MGI:5508294 NCBI chr11:70,234,973...70,279,465
Ensembl chr11:70,234,978...70,242,857 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28760
    cellular process 18484
      vesicle-mediated transport 1669
        endocytosis 776
          phagocytosis 251
            apoptotic cell clearance 47
              engulfment of apoptotic cell 15
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 3
Path 2
Term Annotations click to browse term
  biological_process 28760
    localization 5682
      establishment of localization 4979
        transport 4660
          vesicle-mediated transport 1669
            endocytosis 776
              phagocytosis 251
                phagocytosis, engulfment 66
                  engulfment of apoptotic cell 15
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 3
paths to the root