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ONTOLOGY REPORT - ANNOTATIONS

Term:engulfment of apoptotic cell
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Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse


show annotations for term's descendants           Sort by:
engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IMP
IBA
ISS
IEA		 (PMID:24509909) UniProt
GO_Central
Ensembl		 PMID:24509909 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:142,449,649...142,545,007
Ensembl chr 8:142,449,430...142,545,009 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G MEGF10 multiple EGF like domains 10 involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:27170117) UniProt
MGI
Ensembl		 PMID:27170117 GO_REF:0000024 GO_REF:0000107 NCBI chr 5:127,229,300...127,461,222
Ensembl chr 5:127,290,796...127,465,737 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 7:6,374,527...6,403,967
Ensembl chr 7:6,374,527...6,403,967 		JBrowse link
G RAC3 Rac family small GTPase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:82,031,678...82,034,204
Ensembl chr17:82,031,678...82,034,204 		JBrowse link
G THBS1 thrombospondin 1 involved_in IDA (PMID:16882710) BHF-UCL PMID:16882710 NCBI chr15:39,581,079...39,599,466
Ensembl chr15:39,581,079...39,599,466 		JBrowse link
G XKR4 XK related 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:55,102,028...55,542,054
Ensembl chr 8:55,102,028...55,542,054 		JBrowse link
G XKR5 XK related 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:6,808,517...6,835,524
Ensembl chr 8:6,808,517...6,835,524 		JBrowse link
G XKR6 XK related 6 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:10,896,045...11,201,833
Ensembl chr 8:10,896,045...11,201,833 		JBrowse link
G XKR7 XK related 7 involved_in IBA GO_Central GO_REF:0000033 NCBI chr20:31,968,151...32,003,387
Ensembl chr20:31,968,151...32,003,387 		JBrowse link
G XKR8 XK related 8 involved_in IEA
IBA
IDA		 (PMID:23845944) Ensembl
GO_Central
UniProt		 PMID:23845944 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:27,959,973...27,968,093
Ensembl chr 1:27,959,588...27,968,093 		JBrowse link
G XKR9 XK related 9 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 8:70,669,339...71,065,805
Ensembl chr 8:70,669,339...70,790,371 		JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISS Alzheimers_University_of_Toronto GO_REF:0000024 NCBI chr19:1,040,107...1,065,572
Ensembl chr19:1,039,997...1,065,572 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IMP (PMID:24990881) UniProt PMID:24990881 NCBI chr 6:41,158,508...41,163,116
Ensembl chr 6:41,158,506...41,163,186 		JBrowse link
regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19789
    cellular process 18958
      vesicle-mediated transport 1749
        endocytosis 804
          phagocytosis 262
            apoptotic cell clearance 49
              engulfment of apoptotic cell 15
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 3
Path 2
Term Annotations click to browse term
  biological_process 19789
    localization 5916
      establishment of localization 5203
        transport 4871
          vesicle-mediated transport 1749
            endocytosis 804
              phagocytosis 262
                phagocytosis, engulfment 59
                  engulfment of apoptotic cell 15
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 3
paths to the root