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ONTOLOGY REPORT - ANNOTATIONS

Term:engulfment of apoptotic cell
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Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse

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engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr16:63,469,187...63,482,627
Ensembl chr16:63,469,192...63,485,322 		JBrowse link
G LOC103237529 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:136,704,318...136,784,581
Ensembl chr 8:136,704,341...136,783,991 		JBrowse link
G MEGF10 multiple EGF like domains 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27170117) Ensembl
MGI		 PMID:27170117 GO_REF:0000107 NCBI chr23:30,028,154...30,405,033
Ensembl chr23:30,234,489...30,404,996 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr28:15,583,609...15,610,753
Ensembl chr28:15,583,516...15,610,328 		JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr19:19,930,799...19,949,381
Ensembl chr19:19,929,892...19,949,376 		JBrowse link
G RAC3 Rac family small GTPase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr16:73,919,086...73,921,647
Ensembl chr16:73,919,128...73,925,277 		JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 9:70,266,735...70,398,839
Ensembl chr 9:70,356,290...70,396,791 		JBrowse link
G RHOBTB2 Rho related BTB domain containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:21,069,255...21,098,000
Ensembl chr 8:21,079,411...21,097,026 		JBrowse link
G RHOG ras homolog family member G involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 1:62,881,857...62,896,073
Ensembl chr 1:62,881,941...62,895,529 		JBrowse link
G RHOH ras homolog family member H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr27:10,061,316...10,109,124
Ensembl chr27:10,062,014...10,062,589 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr26:43,410,693...43,427,816
Ensembl chr26:43,410,580...43,427,812 		JBrowse link
G XKR5 XK related 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:6,589,913...6,616,045
Ensembl chr 8:6,590,302...6,615,308 		JBrowse link
G XKR6 XK related 6 involved_in IEA TreeGrafter GO_REF:0000118 Ensembl chr 8:8,172,082...8,204,775 JBrowse link
G XKR7 XK related 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 2:36,357,516...36,387,284
Ensembl chr 2:36,358,337...36,385,140 		JBrowse link
G XKR8 XK related 8 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr20:104,830,967...104,851,913
Ensembl chr20:104,842,157...104,851,280 		JBrowse link
G XKR9 XK related 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:66,406,484...66,463,500
Ensembl chr 8:66,441,550...66,463,496 		JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC103233590 phospholipid-transporting ATPase ABCA7 involved_in ISO (MGI:3662940|PMID:16908670)
(PMID:16908670)		 Alzheimers_University_of_Toronto PMID:16908670 MGI:3662940 NCBI chr 6:792,684...821,522
Ensembl chr 6:792,783...821,375 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:30,965,091...30,999,073
Ensembl chr17:30,994,357...30,999,087 		JBrowse link
regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase involved_in ISO (MGI:5436199|PMID:22503541), (MGI:5508294|PMID:11278875) UniProt PMID:11278875 PMID:22503541 MGI:5436199 MGI:5508294 NCBI chr16:4,112,795...4,121,764
Ensembl chr16:4,111,151...4,121,645 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17106
    cellular process 16633
      vesicle-mediated transport 1596
        endocytosis 704
          phagocytosis 232
            apoptotic cell clearance 52
              engulfment of apoptotic cell 19
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 3
Path 2
Term Annotations click to browse term
  biological_process 17106
    localization 5438
      establishment of localization 4719
        transport 4416
          vesicle-mediated transport 1596
            endocytosis 704
              phagocytosis 232
                phagocytosis, engulfment 63
                  engulfment of apoptotic cell 19
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 3
paths to the root