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ONTOLOGY REPORT - ANNOTATIONS


Term:engulfment of apoptotic cell
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Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse



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engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:36,627,791...36,649,013
Ensembl chr13:36,614,498...36,690,936
JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:20,204,203...20,215,081
Ensembl chr 9:20,204,220...20,214,236
JBrowse link
G LOC119877912 beclin-1 involved_in IEA Ensembl GO_REF:0000107
G LOC119881459 ras-related C3 botulinum toxin substrate 1 involved_in IBA GO_Central GO_REF:0000033
G MEGF10 multiple EGF like domains 10 involved_in
acts_upstream_of_or_within
IEA
ISO
(PMID:27170117) Ensembl
MGI
PMID:27170117 GO_REF:0000107 NCBI chr11:16,359,648...16,574,882
Ensembl chr11:16,378,669...16,617,335
JBrowse link
G RAC1 Rac family small GTPase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 6:11,726,259...11,758,532
Ensembl chr 6:11,655,494...11,757,216
JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr30:6,770,212...6,786,875
Ensembl chr30:6,769,470...6,784,915
JBrowse link
G XKR8 XK related 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:72,419,950...72,426,315
Ensembl chr 2:72,418,872...72,450,737
JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:3662940|PMID:16908670)
(PMID:16908670)
Alzheimers_University_of_Toronto PMID:16908670 MGI:3662940 NCBI chr20:57,668,371...57,684,111
Ensembl chr20:57,667,706...57,677,342
JBrowse link
G TREML1 triggering receptor expressed on myeloid cells like 1 involved_in ISO (PMID:24990881) UniProt PMID:24990881 NCBI chr12:9,915,692...9,928,322
Ensembl chr12:9,915,677...9,928,174
JBrowse link
regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:31,883,544...31,891,357
Ensembl chr 5:31,882,501...32,038,119
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17088
    cellular process 16614
      vesicle-mediated transport 1487
        endocytosis 656
          phagocytosis 211
            apoptotic cell clearance 41
              engulfment of apoptotic cell 11
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 3
Path 2
Term Annotations click to browse term
  biological_process 17088
    localization 5316
      establishment of localization 4649
        transport 4362
          vesicle-mediated transport 1487
            endocytosis 656
              phagocytosis 211
                phagocytosis, engulfment 52
                  engulfment of apoptotic cell 11
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 3
paths to the root