Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

ONTOLOGY REPORT - ANNOTATIONS

Term:engulfment of apoptotic cell
go back to main search page
Accession:GO:0043652 term browser browse the term
Definition:The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
Comment:This term should be used to annotate gene products from the engulfing cell that facilitate phagocytosis of apoptotic cells. It should not be mistaken with GO:0070782 'phosphatidylserine exposure on apoptotic cell surface', a process occurring in apoptotic cells that acts as a signal for engulfing cells. If gene products involved in such instances of phosphatidylserine exposure are shown to have a positive effect on engulfment, they may be annotated to GO:1901076 'positive regulation of engulfment of apoptotic cell'.
Synonyms:exact_synonym: engulfment of apoptotic cell corpse;   engulfment of cell corpse


show annotations for term's descendants           Sort by:
engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRB1 adhesion G protein-coupled receptor B1 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 8:139,154,065...139,251,115
Ensembl chr 8:142,220,827...142,301,070 		JBrowse link
G BECN1 beclin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:14,493,619...14,507,809
Ensembl chr17:14,719,781...14,733,286 		JBrowse link
G LOC100989777 ras-related C3 botulinum toxin substrate 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:141,918,410...141,919,483 JBrowse link
G LRRC45 leucine rich repeat containing 45 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:76,427,929...76,435,779
Ensembl chr17:82,133,217...82,143,623 		JBrowse link
G MEGF10 multiple EGF like domains 10 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:27170117) Ensembl
MGI		 PMID:27170117 GO_REF:0000107 NCBI chr 5:122,639,155...122,877,324
Ensembl chr 5:128,466,095...128,641,043 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 7:7,039,379...7,068,866 JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026 		JBrowse link
G RAC3 Rac family small GTPase 3 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr17:76,436,264...76,439,492
Ensembl chr17:82,133,217...82,143,623 		JBrowse link
G RHOBTB1 Rho related BTB domain containing 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr10:57,410,347...57,541,038
Ensembl chr10:59,740,662...59,815,536 		JBrowse link
G RHOBTB2 Rho related BTB domain containing 2 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:22,246,075...22,269,443
Ensembl chr 8:19,183,931...19,209,420 		JBrowse link
G RHOG ras homolog family member G involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr11:3,698,179...3,712,402
Ensembl chr11:3,811,877...3,812,452 		JBrowse link
G RHOH ras homolog family member H involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 4:34,517,487...34,569,934
Ensembl chr 4:40,419,549...40,420,124 		JBrowse link
G THBS1 thrombospondin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:18,521,802...18,538,172
Ensembl chr15:36,776,756...36,793,170 		JBrowse link
G XKR4 XK related 4 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:51,541,410...51,982,587
Ensembl chr 8:48,914,778...49,336,906 		JBrowse link
G XKR5 XK related 5 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:445,644...472,659
Ensembl chr 8:6,812,607...6,839,844 		JBrowse link
G XKR7 XK related 7 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr20:28,263,026...28,297,736
Ensembl chr20:29,392,600...29,420,363 		JBrowse link
G XKR8 XK related 8 involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr 1:27,219,682...27,228,381
Ensembl chr 1:28,259,993...28,266,978 		JBrowse link
G XKR9 XK related 9 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 8:67,194,689...67,259,983
Ensembl chr 8:68,855,081...68,920,235 		JBrowse link
positive regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA7 ATP binding cassette subfamily A member 7 involved_in ISO (MGI:3662940|PMID:16908670)
(PMID:16908670)		 Alzheimers_University_of_Toronto PMID:16908670 MGI:3662940 NCBI chr19:62,811...77,897
Ensembl chr19:1,018,095...1,042,104 		JBrowse link
G TREM2 triggering receptor expressed on myeloid cells 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:40,735,483...40,740,208
Ensembl chr 6:42,043,900...42,048,578 		JBrowse link
regulation of engulfment of apoptotic cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX15 arachidonate 15-lipoxygenase involved_in ISO (MGI:5436199|PMID:22503541), (MGI:5508294|PMID:11278875) UniProt PMID:11278875 PMID:22503541 MGI:5436199 MGI:5508294 NCBI chr17:4,686,339...4,696,877
Ensembl chr17:4,677,125...4,687,669 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16786
    cellular process 16372
      vesicle-mediated transport 1571
        endocytosis 697
          phagocytosis 227
            apoptotic cell clearance 52
              engulfment of apoptotic cell 21
                negative regulation of engulfment of apoptotic cell 0
                positive regulation of engulfment of apoptotic cell 2
                regulation of engulfment of apoptotic cell + 3
Path 2
Term Annotations click to browse term
  biological_process 16786
    localization 5352
      establishment of localization 4650
        transport 4352
          vesicle-mediated transport 1571
            endocytosis 697
              phagocytosis 227
                phagocytosis, engulfment 62
                  engulfment of apoptotic cell 21
                    negative regulation of engulfment of apoptotic cell 0
                    positive regulation of engulfment of apoptotic cell 2
                    regulation of engulfment of apoptotic cell + 3
paths to the root