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ONTOLOGY REPORT - ANNOTATIONS


Term:dicarboxylic acid biosynthetic process
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Accession:GO:0043650 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
Synonyms:exact_synonym: dicarboxylate biosynthesis;   dicarboxylate biosynthetic process;   dicarboxylic acid anabolism;   dicarboxylic acid biosynthesis;   dicarboxylic acid formation;   dicarboxylic acid synthesis


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10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr 7:88,471,317...88,533,690
Ensembl chr 7:88,471,414...88,537,600
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:15,140,929...15,330,265
Ensembl chr 1:15,140,898...15,329,966
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:53641|PMID:4193185)
GO_Central
MGI
PMID:4193185 PMID:21873635 MGI:53641 NCBI chr14:110,608,422...110,635,825
Ensembl chr14:110,608,430...110,635,874
JBrowse link
G GOT1L1 glutamic-oxaloacetic transaminase 1 like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:48,500,156...48,506,992
Ensembl chr15:48,500,068...48,507,021
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:53641|PMID:4193185) Ensembl
MGI
PMID:4193185 GO_REF:0000107 MGI:53641 NCBI chr 6:20,407,203...20,431,849
Ensembl chr 6:20,407,198...20,432,068
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLS glutaminase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:95,513,414...95,606,029
Ensembl chr15:95,513,380...95,598,311
JBrowse link
G GLUD1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr14:87,968,850...88,005,375
Ensembl chr14:87,968,850...88,005,550
JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr15:77,895,935...78,021,930
Ensembl chr15:77,895,935...78,098,383
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in IEA
ISS
UniProt GO_REF:0000024 GO_REF:0000104 NCBI chr15:17,121,950...17,164,005
Ensembl chr15:17,106,724...17,163,899
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chr 3:97,580,756...97,595,033
Ensembl chr 3:97,580,851...97,595,021
JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (MGI:3653320|PMID:16697652) MGI PMID:16697652 MGI:3653320 NCBI chr 8:1,809,768...1,934,002
Ensembl chr 8:1,809,785...1,934,024
JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chr10:12,442,877...12,489,417
Ensembl chr10:12,431,982...12,490,409
JBrowse link
G KYNU kynureninase involved_in IEA UniProt GO_REF:0000104 NCBI chr15:8,847,335...8,982,951
Ensembl chr15:8,850,665...8,982,945
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16518
    metabolic process 10370
      small molecule metabolic process 1594
        organic acid metabolic process 871
          organic acid biosynthetic process 265
            carboxylic acid biosynthetic process 255
              dicarboxylic acid biosynthetic process 13
                10-formyltetrahydrofolate biosynthetic process 2
                5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                Kdo2-lipid A biosynthetic process 0
                actinorhodin biosynthetic process 0
                aldaric acid biosynthetic process + 0
                aspartate biosynthetic process 3
                chorismate biosynthetic process 0
                diaminopimelate biosynthetic process 0
                dihydrofolate biosynthetic process 0
                folic acid biosynthetic process 0
                gibberellin 12 biosynthetic process 0
                glutamate biosynthetic process + 3
                glutamate catabolic process to oxaloacetate 0
                oxalate biosynthetic process 0
                prephenate(2-) biosynthetic process 0
                quinolinate biosynthetic process + 5
                tyrosine catabolic process to fumarate 0
Path 2
Term Annotations click to browse term
  biological_process 16518
    metabolic process 10370
      cellular metabolic process 9446
        organic acid metabolic process 871
          oxoacid metabolic process 839
            carboxylic acid metabolic process 822
              dicarboxylic acid metabolic process 100
                dicarboxylic acid biosynthetic process 13
                  10-formyltetrahydrofolate biosynthetic process 2
                  5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                  Kdo2-lipid A biosynthetic process 0
                  actinorhodin biosynthetic process 0
                  aldaric acid biosynthetic process + 0
                  aspartate biosynthetic process 3
                  chorismate biosynthetic process 0
                  diaminopimelate biosynthetic process 0
                  dihydrofolate biosynthetic process 0
                  folic acid biosynthetic process 0
                  gibberellin 12 biosynthetic process 0
                  glutamate biosynthetic process + 3
                  glutamate catabolic process to oxaloacetate 0
                  oxalate biosynthetic process 0
                  prephenate(2-) biosynthetic process 0
                  quinolinate biosynthetic process + 5
                  tyrosine catabolic process to fumarate 0
paths to the root