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ONTOLOGY REPORT - ANNOTATIONS


Term:dicarboxylic acid biosynthetic process
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Accession:GO:0043650 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
Synonyms:exact_synonym: dicarboxylate biosynthesis;   dicarboxylate biosynthetic process;   dicarboxylic acid anabolism;   dicarboxylic acid biosynthesis;   dicarboxylic acid formation;   dicarboxylic acid synthesis


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10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase involved_in ISO
IMP
(MGI:5503248|PMID:23704330) MGI
BHF-UCL
PMID:23704330 GO_REF:0000096 MGI:4834177 MGI:5503248 NCBI chr12:76,254,406...76,319,820
Ensembl chr12:76,255,298...76,319,803
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in
acts_upstream_of_or_within
ISO (MGI:2679797|PMID:12937168) MGI PMID:12937168 GO_REF:0000096 MGI:2679797 MGI:4834177 NCBI chr10:3,972,892...4,167,081
Ensembl chr10:3,973,118...4,167,081
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1, soluble acts_upstream_of_or_within
involved_in
IDA
IBA
(MGI:53641|PMID:4193185)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:4193185 PMID:21873635 MGI:53641 MGI:6201960 NCBI chr19:43,499,752...43,524,605
Ensembl chr19:43,499,752...43,524,605
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr 8:27,197,459...27,223,845
Ensembl chr 8:27,197,459...27,223,828
JBrowse link
G Got2 glutamatic-oxaloacetic transaminase 2, mitochondrial acts_upstream_of_or_within IDA (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr 8:95,864,133...95,888,401
Ensembl chr 8:95,864,134...95,888,547
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase involved_in IDA
IBA
ISO
(MGI:5320252|PMID:22228304)
(MGI:6201960|PMID:21873635)
UniProt
GO_Central
MGI
PMID:21873635 PMID:22228304 GO_REF:0000096 MGI:4834177 MGI:5320252 MGI:6201960 NCBI chr 1:52,163,449...52,235,009
Ensembl chr 1:52,163,448...52,233,232
JBrowse link
G Gls2 glutaminase 2 (liver, mitochondrial) involved_in IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr10:128,194,635...128,210,004
Ensembl chr10:128,194,457...128,210,004
JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr14:34,310,727...34,345,033
Ensembl chr14:34,310,727...34,345,265
JBrowse link
G Slc25a12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr 2:71,274,270...71,367,781
Ensembl chr 2:71,271,063...71,367,749
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd amino carboxymuconate semialdehyde decarboxylase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 1:127,729,413...127,767,564
Ensembl chr 1:127,729,413...127,767,978
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr17:83,831,348...83,848,981
Ensembl chr17:83,831,156...83,847,963
JBrowse link
G Htt huntingtin acts_upstream_of_or_within IMP (MGI:3653320|PMID:16697652) MGI PMID:16697652 MGI:3653320 NCBI chr 5:34,761,721...34,912,534
Ensembl chr 5:34,761,740...34,912,534
JBrowse link
G Kmo kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) involved_in IEA UniProt GO_REF:0000002 MGI:2152098 NCBI chr 1:175,632,193...175,660,853
Ensembl chr 1:175,620,381...175,662,116
JBrowse link
G Kynu kynureninase involved_in ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 2:43,555,258...43,683,048
Ensembl chr 2:43,555,329...43,682,715
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23325
    metabolic process 11138
      small molecule metabolic process 1703
        organic acid metabolic process 963
          organic acid biosynthetic process 295
            carboxylic acid biosynthetic process 288
              dicarboxylic acid biosynthetic process 14
                10-formyltetrahydrofolate biosynthetic process 2
                5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                Kdo2-lipid A biosynthetic process 0
                actinorhodin biosynthetic process 0
                aldaric acid biosynthetic process + 0
                aspartate biosynthetic process 3
                chorismate biosynthetic process 0
                diaminopimelate biosynthetic process 0
                dihydrofolate biosynthetic process 0
                folic acid biosynthetic process 0
                gibberellin 12 biosynthetic process 0
                glutamate biosynthetic process + 4
                glutamate catabolic process to oxaloacetate 0
                oxalate biosynthetic process 0
                prephenate(2-) biosynthetic process 0
                quinolinate biosynthetic process + 5
                tyrosine catabolic process to fumarate 0
Path 2
Term Annotations click to browse term
  biological_process 23325
    metabolic process 11138
      cellular metabolic process 10014
        organic acid metabolic process 963
          oxoacid metabolic process 926
            carboxylic acid metabolic process 909
              dicarboxylic acid metabolic process 97
                dicarboxylic acid biosynthetic process 14
                  10-formyltetrahydrofolate biosynthetic process 2
                  5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                  Kdo2-lipid A biosynthetic process 0
                  actinorhodin biosynthetic process 0
                  aldaric acid biosynthetic process + 0
                  aspartate biosynthetic process 3
                  chorismate biosynthetic process 0
                  diaminopimelate biosynthetic process 0
                  dihydrofolate biosynthetic process 0
                  folic acid biosynthetic process 0
                  gibberellin 12 biosynthetic process 0
                  glutamate biosynthetic process + 4
                  glutamate catabolic process to oxaloacetate 0
                  oxalate biosynthetic process 0
                  prephenate(2-) biosynthetic process 0
                  quinolinate biosynthetic process + 5
                  tyrosine catabolic process to fumarate 0
paths to the root