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ONTOLOGY REPORT - ANNOTATIONS


Term:dicarboxylic acid biosynthetic process
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Accession:GO:0043650 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
Synonyms:exact_synonym: dicarboxylate biosynthesis;   dicarboxylate biosynthetic process;   dicarboxylic acid anabolism;   dicarboxylic acid biosynthesis;   dicarboxylic acid formation;   dicarboxylic acid synthesis


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10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in IEA
ISS
IDA
(PMID:1881876) Ensembl
BHF-UCL
PMID:1881876 GO_REF:0000024 GO_REF:0000107 NCBI chr14:64,388,353...64,460,025
Ensembl chr14:64,388,031...64,463,457
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in IDA (PMID:12937168) BHF-UCL PMID:12937168 NCBI chr 6:150,865,684...151,101,887
Ensembl chr 6:150,865,549...151,101,887
Ensembl chr 6:150,865,549...151,101,887
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
(PMID:21873635)
(MGI:53641|PMID:4193185)
GO_Central
MGI
PMID:4193185 PMID:21873635 MGI:53641 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624
JBrowse link
G GOT1L1 glutamic-oxaloacetic transaminase 1 like 1 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:37,933,548...37,940,503
Ensembl chr 8:37,934,281...37,940,124
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
(MGI:53641|PMID:4193185) Ensembl
MGI
PMID:4193185 GO_REF:0000107 MGI:53641 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLS glutaminase involved_in IDA
IBA
TAS
(PMID:16899818), (PMID:22049910)
(PMID:21873635)
(PMID:21757002)
UniProt
GO_Central
BHF-UCL
PMID:16899818 PMID:21757002 PMID:21873635 PMID:22049910 NCBI chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
Ensembl chr 2:190,880,821...190,965,552
JBrowse link
G GLS2 glutaminase 2 involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:56,470,952...56,488,161
Ensembl chr12:56,470,944...56,488,414
JBrowse link
G GLUD1 glutamate dehydrogenase 1 involved_in IDA (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr10:87,050,202...87,094,843
Ensembl chr10:87,050,202...87,094,843
JBrowse link
G GLUD2 glutamate dehydrogenase 2 involved_in IDA (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr  X:121,047,610...121,050,094
Ensembl chr  X:121,047,610...121,050,094
JBrowse link
G SLC25A12 solute carrier family 25 member 12 involved_in IEA
ISO
Ensembl
RGD
PMID:19764902 GO_REF:0000107 RGD:13628741 NCBI chr 2:171,783,405...171,894,244
Ensembl chr 2:171,783,405...171,999,859
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in IDA (PMID:12140278) UniProt PMID:12140278 NCBI chr 2:134,838,319...134,902,906
Ensembl chr 2:134,838,616...134,902,034
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in IDA
NAS
(PMID:28792876)
(PMID:12007609), (PMID:7514594)
UniProt PMID:7514594 PMID:12007609 PMID:28792876 NCBI chr 2:42,767,087...42,801,002
Ensembl chr 2:42,767,089...42,792,593
JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (MGI:3653320|PMID:16697652) MGI PMID:16697652 MGI:3653320 NCBI chr 4:3,074,681...3,243,960
Ensembl chr 4:3,041,422...3,243,960
Ensembl chr 4:3,041,422...3,243,960
JBrowse link
G KMO kynurenine 3-monooxygenase involved_in IEA UniProt GO_REF:0000104 NCBI chr 1:241,531,883...241,595,642
Ensembl chr 1:241,532,134...241,595,642
JBrowse link
G KYNU kynureninase involved_in IDA (PMID:9291104) UniProt PMID:9291104 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18680
    metabolic process 12220
      small molecule metabolic process 2035
        organic acid metabolic process 1153
          organic acid biosynthetic process 340
            carboxylic acid biosynthetic process 332
              dicarboxylic acid biosynthetic process 15
                10-formyltetrahydrofolate biosynthetic process 2
                5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                Kdo2-lipid A biosynthetic process 0
                actinorhodin biosynthetic process 0
                aldaric acid biosynthetic process + 0
                aspartate biosynthetic process 3
                chorismate biosynthetic process 0
                diaminopimelate biosynthetic process 0
                dihydrofolate biosynthetic process 0
                folic acid biosynthetic process 0
                gibberellin 12 biosynthetic process 0
                glutamate biosynthetic process + 5
                glutamate catabolic process to oxaloacetate 0
                oxalate biosynthetic process 0
                prephenate(2-) biosynthetic process 0
                quinolinate biosynthetic process + 5
                tyrosine catabolic process to fumarate 0
Path 2
Term Annotations click to browse term
  biological_process 18680
    metabolic process 12220
      cellular metabolic process 11248
        organic acid metabolic process 1153
          oxoacid metabolic process 1117
            carboxylic acid metabolic process 1085
              dicarboxylic acid metabolic process 114
                dicarboxylic acid biosynthetic process 15
                  10-formyltetrahydrofolate biosynthetic process 2
                  5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                  Kdo2-lipid A biosynthetic process 0
                  actinorhodin biosynthetic process 0
                  aldaric acid biosynthetic process + 0
                  aspartate biosynthetic process 3
                  chorismate biosynthetic process 0
                  diaminopimelate biosynthetic process 0
                  dihydrofolate biosynthetic process 0
                  folic acid biosynthetic process 0
                  gibberellin 12 biosynthetic process 0
                  glutamate biosynthetic process + 5
                  glutamate catabolic process to oxaloacetate 0
                  oxalate biosynthetic process 0
                  prephenate(2-) biosynthetic process 0
                  quinolinate biosynthetic process + 5
                  tyrosine catabolic process to fumarate 0
paths to the root