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ONTOLOGY REPORT - ANNOTATIONS


Term:dicarboxylic acid biosynthetic process
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Accession:GO:0043650 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
Synonyms:exact_synonym: dicarboxylate biosynthesis;   dicarboxylate biosynthetic process;   dicarboxylic acid anabolism;   dicarboxylic acid biosynthesis;   dicarboxylic acid formation;   dicarboxylic acid synthesis


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10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in ISO (PMID:12937168) BHF-UCL PMID:12937168 NCBI chr 6:148,679,587...148,919,002
Ensembl chr 6:153,390,498...153,619,884
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLS glutaminase involved_in ISO (PMID:16899818), (PMID:22049910)
(MGI:5320252|PMID:22228304)
UniProt PMID:16899818 PMID:22049910 PMID:22228304 MGI:5320252 NCBI chr2B:78,182,117...78,267,071
Ensembl chr2B:196,098,910...196,183,323
JBrowse link
G GLUD1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr10:83,498,338...83,540,730 JBrowse link
G GLUD2 glutamate dehydrogenase 2 involved_in ISO (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr  X:110,223,978...111,065,243 JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr2B:59,071,123...59,297,327
Ensembl chr2B:176,532,940...176,641,894
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in ISO (PMID:12140278) UniProt PMID:12140278 NCBI chr2B:24,958,661...25,019,901
Ensembl chr2B:138,918,281...138,978,407
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) UniProt PMID:28792876 NCBI chr2A:42,857,216...42,882,738
Ensembl chr2A:43,704,468...43,729,887
JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (MGI:3653320|PMID:16697652) MGI PMID:16697652 MGI:3653320 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730
JBrowse link
G KYNU kynureninase involved_in ISO (PMID:9291104) UniProt PMID:9291104 NCBI chr2B:16,792,401...16,947,766
Ensembl chr2B:146,975,995...147,132,634
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12627
    metabolic process 7928
      small molecule metabolic process 1271
        organic acid metabolic process 689
          organic acid biosynthetic process 220
            carboxylic acid biosynthetic process 214
              dicarboxylic acid biosynthetic process 12
                10-formyltetrahydrofolate biosynthetic process 2
                5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                Kdo2-lipid A biosynthetic process 0
                actinorhodin biosynthetic process 0
                aldaric acid biosynthetic process + 0
                aspartate biosynthetic process 2
                chorismate biosynthetic process 0
                diaminopimelate biosynthetic process 0
                dihydrofolate biosynthetic process 0
                folic acid biosynthetic process 0
                gibberellin 12 biosynthetic process 0
                glutamate biosynthetic process + 4
                glutamate catabolic process to oxaloacetate 0
                oxalate biosynthetic process 0
                prephenate(2-) biosynthetic process 0
                quinolinate biosynthetic process + 4
                tyrosine catabolic process to fumarate 0
Path 2
Term Annotations click to browse term
  biological_process 12627
    metabolic process 7928
      cellular metabolic process 7266
        organic acid metabolic process 689
          oxoacid metabolic process 663
            carboxylic acid metabolic process 652
              dicarboxylic acid metabolic process 80
                dicarboxylic acid biosynthetic process 12
                  10-formyltetrahydrofolate biosynthetic process 2
                  5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                  Kdo2-lipid A biosynthetic process 0
                  actinorhodin biosynthetic process 0
                  aldaric acid biosynthetic process + 0
                  aspartate biosynthetic process 2
                  chorismate biosynthetic process 0
                  diaminopimelate biosynthetic process 0
                  dihydrofolate biosynthetic process 0
                  folic acid biosynthetic process 0
                  gibberellin 12 biosynthetic process 0
                  glutamate biosynthetic process + 4
                  glutamate catabolic process to oxaloacetate 0
                  oxalate biosynthetic process 0
                  prephenate(2-) biosynthetic process 0
                  quinolinate biosynthetic process + 4
                  tyrosine catabolic process to fumarate 0
paths to the root