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ONTOLOGY REPORT - ANNOTATIONS


Term:dicarboxylic acid biosynthetic process
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Accession:GO:0043650 term browser browse the term
Definition:The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
Synonyms:exact_synonym: dicarboxylate biosynthesis;   dicarboxylate biosynthetic process;   dicarboxylic acid anabolism;   dicarboxylic acid biosynthesis;   dicarboxylic acid formation;   dicarboxylic acid synthesis


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10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mthfd1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
RGD PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr 6:99,282,850...99,350,367
Ensembl chr 6:99,282,850...99,350,340
JBrowse link
G Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like involved_in ISO (PMID:12937168) RGD PMID:12937168 NCBI chr 1:40,529,092...40,719,232
Ensembl chr 1:40,529,045...40,719,391
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Got1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(MGI:53641|PMID:4193185)
PMID:21873635
RGD PMID:4193185, PMID:21873635, PMID:21873635 MGI:53641, RGD:13792537, RGD:13792537 NCBI chr 1:263,246,248...263,269,762
Ensembl chr 1:263,246,248...263,269,762
JBrowse link
G Got1l1 glutamic-oxaloacetic transaminase 1-like 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr16:69,022,756...69,035,507
Ensembl chr16:69,022,784...69,028,179
JBrowse link
G Got2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD PMID:4193185 MGI:53641 NCBI chr19:9,587,637...9,613,323
Ensembl chr19:9,587,653...9,613,340
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gls glutaminase involved_in IEA
ISO
IBA
ISS
GO_REF:0000107
(MGI:5320252|PMID:22228304)
PMID:21873635
GO_REF:0000024
(PMID:16899818), (PMID:22049910)
Ensembl
RGD
UniProt
PMID:16899818 PMID:22049910 PMID:22228304, PMID:21873635, PMID:21873635 GO_REF:0000024 GO_REF:0000107 MGI:5320252, RGD:13792537, RGD:13792537 NCBI chr 9:54,212,622...54,284,879
Ensembl chr 9:54,212,767...54,284,872
JBrowse link
G Gls2 glutaminase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635, PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 7:2,605,679...2,621,853
Ensembl chr 7:2,605,719...2,621,852
JBrowse link
G Glud1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) RGD PMID:11032875 NCBI chr16:10,661,486...10,695,557
Ensembl chr16:10,662,021...10,695,557
JBrowse link
G Slc25a12 solute carrier family 25 member 12 IMP RGD PMID:19764902 RGD:13628741 NCBI chr 3:57,881,951...57,998,214
Ensembl chr 3:57,882,370...57,957,346
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acmsd aminocarboxymuconate semialdehyde decarboxylase involved_in ISO
ISS
IEA
(PMID:12140278)
GO_REF:0000024
GO_REF:0000104
RGD
UniProt
PMID:12140278 GO_REF:0000024 GO_REF:0000104 NCBI chr13:44,424,689...44,468,734
Ensembl chr13:44,424,689...44,468,734
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Haao 3-hydroxyanthranilate 3,4-dioxygenase involved_in IEA
ISO
GO_REF:0000104
(PMID:28792876)
UniProt
RGD
PMID:28792876 GO_REF:0000104 NCBI chr 6:7,045,145...7,059,227
Ensembl chr 6:7,045,152...7,058,314
JBrowse link
G Htt huntingtin acts_upstream_of_or_within ISO MGI:1861934|MGI:1861935 (MGI:3653320|PMID:16697652) RGD PMID:16697652 MGI:3653320 NCBI chr14:81,105,139...81,254,637
Ensembl chr14:81,105,139...81,254,637
JBrowse link
G Kmo kynurenine 3-monooxygenase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr13:93,684,324...93,715,378
Ensembl chr13:93,684,437...93,716,227
JBrowse link
G Kynu kynureninase involved_in ISO (PMID:9291104) RGD PMID:9291104 NCBI chr 3:28,416,926...28,566,939
Ensembl chr 3:28,416,954...28,566,928
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20082
    metabolic process 12142
      small molecule metabolic process 1824
        organic acid metabolic process 1018
          organic acid biosynthetic process 298
            carboxylic acid biosynthetic process 290
              dicarboxylic acid biosynthetic process 14
                10-formyltetrahydrofolate biosynthetic process 2
                5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                Kdo2-lipid A biosynthetic process 0
                actinorhodin biosynthetic process 0
                aldaric acid biosynthetic process + 0
                aspartate biosynthetic process 3
                chorismate biosynthetic process 0
                diaminopimelate biosynthetic process 0
                dihydrofolate biosynthetic process 0
                folic acid biosynthetic process 0
                gibberellin 12 biosynthetic process 0
                glutamate biosynthetic process + 4
                glutamate catabolic process to oxaloacetate 0
                oxalate biosynthetic process 0
                prephenate(2-) biosynthetic process 0
                quinolinate biosynthetic process + 5
                tyrosine catabolic process to fumarate 0
Path 2
Term Annotations click to browse term
  biological_process 20082
    metabolic process 12142
      cellular metabolic process 11078
        organic acid metabolic process 1018
          oxoacid metabolic process 980
            carboxylic acid metabolic process 961
              dicarboxylic acid metabolic process 104
                dicarboxylic acid biosynthetic process 14
                  10-formyltetrahydrofolate biosynthetic process 2
                  5,6,7,8-tetrahydromethanopterin biosynthetic process 0
                  Kdo2-lipid A biosynthetic process 0
                  actinorhodin biosynthetic process 0
                  aldaric acid biosynthetic process + 0
                  aspartate biosynthetic process 3
                  chorismate biosynthetic process 0
                  diaminopimelate biosynthetic process 0
                  dihydrofolate biosynthetic process 0
                  folic acid biosynthetic process 0
                  gibberellin 12 biosynthetic process 0
                  glutamate biosynthetic process + 4
                  glutamate catabolic process to oxaloacetate 0
                  oxalate biosynthetic process 0
                  prephenate(2-) biosynthetic process 0
                  quinolinate biosynthetic process + 5
                  tyrosine catabolic process to fumarate 0
paths to the root