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ONTOLOGY REPORT - ANNOTATIONS


Term:dicarboxylic acid metabolic process
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Accession:GO:0043648 term browser browse the term
Definition:The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
Synonyms:exact_synonym: dicarboxylate metabolic process;   dicarboxylate metabolism;   dicarboxylic acid metabolism



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dicarboxylic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOT4 acyl-CoA thioesterase 4 involved_in ISO (PMID:16940157)
(MGI:3663233|PMID:16940157)
HGNC-UCL PMID:16940157 MGI:3663233 NCBI chr14:54,150,843...54,155,119
Ensembl chr14:73,008,909...73,012,561
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:2837211 PMID:7562489 RGD:1627658 RGD:2289377 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 ISO RGD PMID:14522984 RGD:1582383 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
G GRHPR glyoxylate and hydroxypyruvate reductase ISO RGD PMID:2689175 RGD:1599320 NCBI chr 9:37,267,918...37,282,253
Ensembl chr 9:38,192,149...38,206,478
JBrowse link
10-formyltetrahydrofolate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD1 methylenetetrahydrofolate dehydrogenase, cyclohydrolase and formyltetrahydrofolate synthetase 1 involved_in ISO (PMID:1881876)
(MGI:5503248|PMID:23704330)
BHF-UCL PMID:1881876 PMID:23704330 MGI:5503248 NCBI chr14:44,969,573...45,041,296
Ensembl chr14:63,223,484...63,293,881
JBrowse link
G MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like involved_in ISO (PMID:12937168) BHF-UCL PMID:12937168 NCBI chr 6:148,679,587...148,919,002
Ensembl chr 6:153,390,498...153,619,884
JBrowse link
10-formyltetrahydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like ISO RGD PMID:21163947 RGD:7244288 NCBI chr 4:49,889,607...50,034,860
Ensembl chr 4:55,722,237...55,867,117
JBrowse link
2-oxoglutarate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase involved_in ISO (PMID:18620547) UniProt PMID:18620547 NCBI chr 4:162,283,569...162,313,720
Ensembl chr 4:174,353,766...174,383,471
JBrowse link
G DLD dihydrolipoamide dehydrogenase ISO RGD PMID:3571202 RGD:2306876 NCBI chr 7:99,872,020...99,901,884
Ensembl chr 7:112,593,934...112,623,629
JBrowse link
G DLST dihydrolipoamide S-succinyltransferase involved_in ISO (PMID:10806400) RGD
UniProt
PMID:3571202 PMID:10806400 RGD:2306876 NCBI chr14:55,433,358...55,455,876
Ensembl chr14:74,278,128...74,300,133
JBrowse link
G GPT2 glutamic--pyruvic transaminase 2 involved_in ISO (PMID:11863375) UniProt PMID:11863375 NCBI chr16:27,150,159...27,197,006
Ensembl chr16:46,040,439...46,086,840
JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 involved_in ISO (PMID:19935646) UniProt PMID:19935646 NCBI chr2B:95,475,320...95,494,286
Ensembl chr2B:213,599,036...213,617,175
JBrowse link
G IDH3A isocitrate dehydrogenase (NAD(+)) 3 catalytic subunit alpha ISO RGD PMID:938457 RGD:2306828 NCBI chr15:57,078,588...57,099,934
Ensembl chr15:76,043,311...76,064,634
JBrowse link
G IDH3B isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit beta ISO RGD PMID:938457 RGD:2306828 NCBI chr20:2,766,598...2,772,571
Ensembl chr20:2,529,510...2,535,570
JBrowse link
G IDH3G isocitrate dehydrogenase (NAD(+)) 3 non-catalytic subunit gamma ISO RGD PMID:938457 RGD:2306828 NCBI chr  X:143,336,460...143,345,274
Ensembl chr  X:153,222,309...153,231,135
JBrowse link
G KYAT3 kynurenine aminotransferase 3 involved_in ISO (MGI:3835225|PMID:19029248) UniProt PMID:19029248 MGI:3835225 NCBI chr 1:91,636,681...91,708,859
Ensembl chr 1:90,403,072...90,460,426
JBrowse link
G OGDH oxoglutarate dehydrogenase involved_in ISO (PMID:24495017), (PMID:29211711) RGD
UniProt
PMID:3571202 PMID:9712727 PMID:24495017 PMID:29211711 RGD:2306876 RGD:2306877 NCBI chr 7:45,321,559...45,422,515
Ensembl chr 7:45,409,148...45,491,636
JBrowse link
G OGDHL oxoglutarate dehydrogenase L involved_in ISO PMID:18783430 UniProt PMID:18783430 RGD:42721998 NCBI chr10:44,476,006...44,504,578 JBrowse link
G PHYH phytanoyl-CoA 2-hydroxylase involved_in ISO (PMID:16186124) CAFA PMID:16186124 NCBI chr10:13,277,804...13,300,115
Ensembl chr10:13,251,223...13,636,018
JBrowse link
G TAT tyrosine aminotransferase involved_in ISO (PMID:7999802)
(MGI:5430853|PMID:21153519)
UniProt PMID:7999802 PMID:21153519 MGI:5430853 NCBI chr16:53,434,028...53,443,624
Ensembl chr16:71,404,399...71,413,886
JBrowse link
ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ASL argininosuccinate lyase acts_upstream_of_or_within ISO (MGI:3604426|PMID:12559843) MGI PMID:12559843 MGI:3604426 NCBI chr 7:59,971,529...59,988,722
Ensembl chr 7:73,142,842...73,157,472
JBrowse link
G GLUL glutamate-ammonia ligase ISO RGD PMID:28323 RGD:2301547 NCBI chr 1:157,882,258...157,891,562
Ensembl chr 1:161,534,106...161,543,411
JBrowse link
aspartate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
aspartate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDO D-aspartate oxidase involved_in ISO (PMID:9163533) UniProt PMID:9163533 NCBI chr 6:108,199,861...108,223,844
Ensembl chr 6:112,269,271...112,292,980
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 involved_in ISO (PMID:2241899) UniProt PMID:2241899 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 involved_in ISO (PMID:2567216) UniProt PMID:2567216 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
aspartate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADSS2 adenylosuccinate synthase 2 ISO RGD PMID:71897 RGD:5135533 NCBI chr 1:220,020,480...220,063,658
Ensembl chr 1:225,401,544...225,444,984
JBrowse link
G ASS1 argininosuccinate synthase 1 involved_in ISO (PMID:7977368) BHF-UCL PMID:7977368 NCBI chr 9:101,569,442...101,625,899
Ensembl chr 9:130,219,993...130,276,036
JBrowse link
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in ISO (MGI:5926996|PMID:28701731) MGI PMID:28701731 MGI:5926996 NCBI chr15:24,469,225...24,553,163
Ensembl chr15:42,862,112...42,882,316
JBrowse link
G DDO D-aspartate oxidase acts_upstream_of_or_within ISO (MGI:3617951|PMID:16525061) MGI PMID:16525061 MGI:3617951 NCBI chr 6:108,199,861...108,223,844
Ensembl chr 6:112,269,271...112,292,980
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO RGD PMID:2837211 RGD:2289377 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 ISO RGD PMID:12686151 RGD:2289396 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
dicarboxylic acid catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACOT4 acyl-CoA thioesterase 4 involved_in ISO (PMID:16141203) UniProt PMID:16141203 NCBI chr14:54,150,843...54,155,119
Ensembl chr14:73,008,909...73,012,561
JBrowse link
G ACOT8 acyl-CoA thioesterase 8 involved_in ISO (PMID:16141203) UniProt PMID:16141203 NCBI chr20:42,180,734...42,196,466
Ensembl chr20:43,268,264...43,283,989
JBrowse link
dihydrofolate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATIC 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase ISO RGD PMID:8948466 RGD:5144056 NCBI chr2B:102,574,700...102,612,492
Ensembl chr2B:221,159,439...221,197,360
JBrowse link
G DHFR dihydrofolate reductase involved_in ISO (PMID:2303423), (PMID:23707606) RGD
BHF-UCL
PMID:2303423 PMID:3970530 PMID:11502523 PMID:23707606 RGD:1298877 RGD:2300196 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
folic acid metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DHFR dihydrofolate reductase involved_in ISO PMID:20424322 BHF-UCL PMID:20424322 RGD:10054082 NCBI chr 5:34,663,210...34,689,467
Ensembl chr 5:34,938,548...34,967,003
JBrowse link
G FOLR1 folate receptor alpha acts_upstream_of_or_within ISO (MGI:2669340|PMID:12854656) MGI PMID:12854656 MGI:2669340 NCBI chr11:67,268,721...67,275,498
Ensembl chr11:70,492,039...70,498,665
JBrowse link
G MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase involved_in ISO (PMID:11466310)
(MGI:5512657|PMID:24074862)
BHF-UCL
UniProt
PMID:11466310 PMID:24074862 MGI:5512657 NCBI chr 5:8,195,868...8,228,071
Ensembl chr 5:8,017,403...8,049,322
JBrowse link
G SHMT1 serine hydroxymethyltransferase 1 involved_in ISO (PMID:11278996) UniProt PMID:11278996 NCBI chr17:32,870,949...32,905,690
Ensembl chr17:37,849,206...37,884,220
JBrowse link
fumarate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G FH fumarate hydratase involved_in ISO (MGI:5496931|PMID:23643539)
(PMID:26237645), (PMID:30718813), (PMID:30761759)
(PMID:21498518)
RGD
UniProt
PMID:938457 PMID:21498518 PMID:23643539 PMID:26237645 PMID:30718813 More... MGI:5496931 RGD:2306828 NCBI chr 1:217,059,847...217,081,795
Ensembl chr 1:222,041,142...222,064,212
JBrowse link
glutamate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLS glutaminase involved_in ISO (PMID:16899818), (PMID:22049910)
(MGI:5320252|PMID:22228304)
UniProt PMID:16899818 PMID:22049910 PMID:22228304 MGI:5320252 NCBI chr2B:78,182,117...78,267,071
Ensembl chr2B:196,098,910...196,183,323
JBrowse link
G GLUD1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr10:83,498,338...83,540,730 JBrowse link
G GLUD2 glutamate dehydrogenase 2 involved_in ISO (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr  X:110,223,978...111,065,243 JBrowse link
G SLC25A12 solute carrier family 25 member 12 ISO RGD PMID:19764902 RGD:13628741 NCBI chr2B:59,071,123...59,297,327
Ensembl chr2B:176,532,940...176,641,894
JBrowse link
glutamate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GLUD1 glutamate dehydrogenase 1 involved_in ISO (PMID:11032875), (PMID:6121377) BHF-UCL PMID:6121377 PMID:11032875 NCBI chr10:83,498,338...83,540,730 JBrowse link
G GLUD2 glutamate dehydrogenase 2 involved_in ISO (PMID:11032875) BHF-UCL PMID:11032875 NCBI chr  X:110,223,978...111,065,243 JBrowse link
glutamate catabolic process to 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD
MGI
PMID:4193185 PMID:16489927 MGI:53641 RGD:13504861 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD
MGI
PMID:4193185 PMID:16489927 MGI:53641 RGD:13504861 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
glutamate catabolic process to aspartate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GOT1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) MGI PMID:4193185 MGI:53641 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
glutamate catabolic process via 2-oxoglutarate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADHFE1 alcohol dehydrogenase iron containing 1 involved_in ISO (PMID:16435184) UniProt PMID:16435184 NCBI chr 8:62,975,711...63,012,102 JBrowse link
glutamate decarboxylation to succinate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GAD2 glutamate decarboxylase 2 ISO RGD PMID:8999827 RGD:1625237 NCBI chr10:26,392,877...26,481,859
Ensembl chr10:26,759,243...26,843,197
JBrowse link
glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AADAT aminoadipate aminotransferase involved_in ISO (PMID:18620547) UniProt PMID:18620547 NCBI chr 4:162,283,569...162,313,720
Ensembl chr 4:174,353,766...174,383,471
JBrowse link
G ALDH18A1 aldehyde dehydrogenase 18 family member A1 involved_in ISO (PMID:11092761) UniProt PMID:11092761 NCBI chr10:92,216,639...92,267,525
Ensembl chr10:95,723,099...95,774,095
JBrowse link
G ALDH5A1 aldehyde dehydrogenase 5 family member A1 acts_upstream_of_or_within ISO (MGI:3767902|PMID:17854388) MGI PMID:17854388 MGI:3767902 NCBI chr 6:24,332,093...24,370,764
Ensembl chr 6:24,665,026...24,705,151
JBrowse link
G BLOC1S6 biogenesis of lysosomal organelles complex 1 subunit 6 involved_in ISO (MGI:5926996|PMID:28701731) MGI PMID:28701731 MGI:5926996 NCBI chr15:24,469,225...24,553,163
Ensembl chr15:42,862,112...42,882,316
JBrowse link
G DGLUCY D-glutamate cyclase involved_in ISO (MGI:5901965|PMID:28266638) UniProt PMID:28266638 MGI:5901965 NCBI chr14:71,678,891...71,851,806
Ensembl chr14:91,089,132...91,199,043
JBrowse link
G FPGS folylpolyglutamate synthase involved_in ISO (PMID:3619447) BHF-UCL PMID:3619447 NCBI chr 9:98,921,986...98,933,542
Ensembl chr 9:127,593,592...127,604,200
JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit involved_in ISO (PMID:12663448), (PMID:2294991), (PMID:9841880) UniProt PMID:2294991 PMID:9841880 PMID:12663448 NCBI chr 6:53,052,145...53,102,794
Ensembl chr 6:54,687,315...54,734,994
JBrowse link
G GCLM glutamate-cysteine ligase modifier subunit involved_in ISO (PMID:9841880), (PMID:9895302) UniProt PMID:9841880 PMID:9895302 NCBI chr 1:96,548,850...96,573,273
Ensembl chr 1:95,278,665...95,297,893
JBrowse link
G GGT1 gamma-glutamyltransferase 1 involved_in ISO (PMID:21447318), (PMID:24047895) UniProt PMID:21447318 PMID:24047895 NCBI chr22:5,424,334...5,469,705 JBrowse link
G GLUD2 glutamate dehydrogenase 2 involved_in ISO (PMID:8207021) UniProt PMID:8207021 NCBI chr  X:110,223,978...111,065,243 JBrowse link
G GLUL glutamate-ammonia ligase ISO RGD PMID:4403443 RGD:2301548 NCBI chr 1:157,882,258...157,891,562
Ensembl chr 1:161,534,106...161,543,411
JBrowse link
G NAGS N-acetylglutamate synthase acts_upstream_of_or_within ISO (MGI:2388220|PMID:12049647) MGI PMID:12049647 MGI:2388220 NCBI chr17:13,386,207...13,390,724
Ensembl chr17:13,553,424...13,558,269
JBrowse link
G TAT tyrosine aminotransferase involved_in ISO (PMID:7999802)
(MGI:5430853|PMID:21153519)
UniProt PMID:7999802 PMID:21153519 MGI:5430853 NCBI chr16:53,434,028...53,443,624
Ensembl chr16:71,404,399...71,413,886
JBrowse link
malate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G D2HGDH D-2-hydroxyglutarate dehydrogenase involved_in ISO (PMID:33431826) UniProt PMID:33431826 NCBI chr2B:129,012,616...129,045,873
Ensembl chr2B:247,799,219...247,830,621
JBrowse link
G FH fumarate hydratase involved_in ISO (PMID:21498518)
(PMID:30761759)
RGD
UniProt
PMID:938457 PMID:21498518 PMID:30761759 RGD:2306828 NCBI chr 1:217,059,847...217,081,795
Ensembl chr 1:222,041,142...222,064,212
JBrowse link
G LIPF lipase F, gastric type acts_upstream_of_or_within ISO PMID:15809022 MGI PMID:15809022 RGD:1582471 NCBI chr10:85,389,165...85,403,492
Ensembl chr10:88,892,525...88,906,898
JBrowse link
G MDH1 malate dehydrogenase 1 ISO RGD PMID:12351438 PMID:17447164 RGD:1624966 RGD:2303499 NCBI chr2A:63,658,933...63,677,257
Ensembl chr2A:64,785,132...64,803,631
JBrowse link
G MDH2 malate dehydrogenase 2 involved_in ISO (PMID:16740313)
(PMID:6576816)
RGD
UniProt
PMID:938457 PMID:1898089 PMID:6576816 PMID:12351438 PMID:16740313 RGD:1582472 RGD:2303499 RGD:2306828 NCBI chr 7:67,953,759...67,973,270
Ensembl chr 7:82,497,800...82,516,526
JBrowse link
G ME1 malic enzyme 1 involved_in ISO (PMID:7622060), (PMID:8187880) UniProt PMID:7622060 PMID:8187880 NCBI chr 6:81,107,569...81,320,050
Ensembl chr 6:84,382,732...84,595,701
JBrowse link
G ME3 malic enzyme 3 involved_in ISO (PMID:7818469) UniProt PMID:7818469 NCBI chr11:81,490,947...81,728,589
Ensembl chr11:85,104,477...85,222,822
JBrowse link
malonate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSF3 acyl-CoA synthetase family member 3 involved_in ISO (PMID:21642549), (PMID:21846720) UniProt PMID:21642549 PMID:21846720 NCBI chr16:69,842,709...69,907,075
Ensembl chr16:89,467,997...89,523,825
JBrowse link
negative regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATCAY ATCAY kinesin light chain interacting caytaxin involved_in ISO (PMID:16899818) UniProt PMID:16899818 NCBI chr19:2,905,615...2,953,079
Ensembl chr19:3,854,423...3,900,175
JBrowse link
negative regulation of quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACMSD aminocarboxymuconate semialdehyde decarboxylase involved_in ISO (PMID:12140278) UniProt PMID:12140278 NCBI chr2B:24,958,661...25,019,901
Ensembl chr2B:138,918,281...138,978,407
JBrowse link
oxalate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 involved_in ISO (PMID:21896830) BHF-UCL PMID:21896830 NCBI chr10:94,204,627...94,233,312 JBrowse link
oxaloacetate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACLY ATP citrate lyase involved_in ISO (PMID:1371749) BHF-UCL PMID:1371749 NCBI chr17:15,385,335...15,447,269
Ensembl chr17:15,615,994...15,664,800
JBrowse link
G CS citrate synthase ISO RGD PMID:818082 PMID:938457 PMID:5820645 RGD:2306824 RGD:2306825 RGD:2306828 NCBI chr12:32,614,982...32,643,719
Ensembl chr12:32,867,225...32,895,854
JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD
MGI
PMID:4193185 PMID:16489927 MGI:53641 RGD:13504861 NCBI chr10:96,012,345...96,046,266
Ensembl chr10:99,506,205...99,540,178
JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 acts_upstream_of_or_within ISO (MGI:53641|PMID:4193185) RGD
MGI
PMID:4193185 PMID:16489927 MGI:53641 RGD:13504861 NCBI chr16:38,995,770...39,022,750
Ensembl chr16:58,120,781...58,147,378
JBrowse link
G MDH1 malate dehydrogenase 1 ISO RGD PMID:17447164 RGD:1624966 NCBI chr2A:63,658,933...63,677,257
Ensembl chr2A:64,785,132...64,803,631
JBrowse link
G MDH2 malate dehydrogenase 2 ISO RGD PMID:938457 RGD:2306828 NCBI chr 7:67,953,759...67,973,270
Ensembl chr 7:82,497,800...82,516,526
JBrowse link
G NIT2 nitrilase family member 2 involved_in ISO (PMID:22674578) BHF-UCL PMID:22674578 NCBI chr 3:97,427,470...97,448,354
Ensembl chr 3:104,109,804...104,130,535
JBrowse link
G PC pyruvate carboxylase ISO RGD PMID:5773282 PMID:6049928 PMID:15507531 RGD:1601554 RGD:2302971 RGD:2302972 NCBI chr11:62,205,644...62,317,917
Ensembl chr11:65,527,662...65,551,396
JBrowse link
G PCK1 phosphoenolpyruvate carboxykinase 1 involved_in ISO (MGI:6119963|PMID:29230018)
PMID:26322521
PMID:26709450
PMID:30193097
PMID:31461616
(PMID:26792594)
(PMID:30193097)
RGD
UniProt
PMID:4303362 PMID:6049928 PMID:16125296 PMID:26322521 PMID:26709450 More... MGI:6119963 RGD:13825433 RGD:1601233 RGD:2302850 RGD:2302971 RGD:30309906 RGD:30309918 RGD:30309937 NCBI chr20:53,901,738...53,907,090
Ensembl chr20:55,179,429...55,184,920
JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial ISO RGD PMID:6049928 RGD:2302971 NCBI chr14:4,872,276...4,882,118
Ensembl chr14:22,996,813...23,006,775
JBrowse link
positive regulation of ammonia assimilation cycle term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in ISO (MGI:5306122|PMID:21757002) BHF-UCL PMID:21757002 MGI:5306122 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058
JBrowse link
positive regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in ISO (MGI:5306122|PMID:21757002) BHF-UCL PMID:21757002 MGI:5306122 NCBI chr12:98,052,778...98,144,085
Ensembl chr12:101,457,885...101,548,058
JBrowse link
quinolinate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase involved_in ISO (PMID:28792876) UniProt PMID:28792876 NCBI chr2A:42,857,216...42,882,738
Ensembl chr2A:43,704,468...43,729,887
JBrowse link
G HTT huntingtin acts_upstream_of_or_within ISO (MGI:3653320|PMID:16697652) MGI PMID:16697652 MGI:3653320 NCBI chr 4:3,215,081...3,388,587
Ensembl chr 4:3,128,718...3,283,730
JBrowse link
G KYNU kynureninase involved_in ISO (PMID:9291104) UniProt PMID:9291104 NCBI chr2B:16,792,401...16,947,766
Ensembl chr2B:146,975,995...147,132,634
JBrowse link
quinolinate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G QPRT quinolinate phosphoribosyltransferase involved_in
acts_upstream_of_or_within
ISO (PMID:24038671), (PMID:3409840), (PMID:9473669)
(PMID:9473669)
UniProt
MGI
PMID:3409840 PMID:9473669 PMID:24038671
quinolinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HAAO 3-hydroxyanthranilate 3,4-dioxygenase ISO RGD PMID:2940338 PMID:3112306 PMID:9870556 RGD:2290301 RGD:2290302 RGD:2290370 NCBI chr2A:42,857,216...42,882,738
Ensembl chr2A:43,704,468...43,729,887
JBrowse link
G QPRT quinolinate phosphoribosyltransferase ISO RGD PMID:8694849 RGD:2289495
regulation of glutamate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APC APC regulator of WNT signaling pathway ISO RGD PMID:19858196 RGD:6484536 NCBI chr 5:108,070,697...108,208,273
Ensembl chr 5:113,904,352...114,009,709
JBrowse link
G SLC7A11 solute carrier family 7 member 11 acts_upstream_of_or_within ISO (MGI:4948153|PMID:21490221), (MGI:5616960|PMID:25429150)
(MGI:5562570|PMID:24548853)
MGI PMID:21490221 PMID:24548853 PMID:25429150 MGI:4948153 MGI:5562570 MGI:5616960 NCBI chr 4:130,529,677...130,601,396
Ensembl chr 4:141,849,343...141,959,849
JBrowse link
succinate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALDH5A1 aldehyde dehydrogenase 5 family member A1 acts_upstream_of_or_within
involved_in
ISO (MGI:3759189|PMID:12065715)
PMID:7814412
RGD
MGI
UniProt
PMID:7262085 PMID:7814412 PMID:12065715 PMID:12527414 PMID:12871571 MGI:3759189 RGD:1304407 RGD:1600512 RGD:1600514 RGD:632258 NCBI chr 6:24,332,093...24,370,764
Ensembl chr 6:24,665,026...24,705,151
JBrowse link
G SDHA succinate dehydrogenase complex flavoprotein subunit A involved_in ISO (PMID:7550341) RGD
UniProt
PMID:7550341 PMID:16520240 RGD:2306906 NCBI chr 5:192,786...234,089 JBrowse link
G SDHB succinate dehydrogenase complex iron sulfur subunit B ISO RGD PMID:16520240 RGD:2306906 NCBI chr 1:15,962,383...15,998,056
Ensembl chr 1:17,018,542...17,054,509
JBrowse link
G SUCLA2 succinate-CoA ligase ADP-forming subunit beta ISO RGD PMID:17403370 RGD:2306915 NCBI chr13:29,095,062...29,189,618
Ensembl chr13:47,797,472...47,856,138
JBrowse link
G SUCLG1 succinate-CoA ligase GDP/ADP-forming subunit alpha ISO RGD PMID:17403370 RGD:2306915 NCBI chr2A:84,476,814...84,512,920
Ensembl chr2A:86,035,723...86,066,622
JBrowse link
G SUCLG2 succinate-CoA ligase GDP-forming subunit beta ISO RGD PMID:17403370 RGD:2306915 NCBI chr 3:67,277,348...67,563,181
Ensembl chr 3:68,647,738...68,931,891
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12661
    metabolic process 7934
      cellular metabolic process 7256
        organic acid metabolic process 700
          oxoacid metabolic process 677
            carboxylic acid metabolic process 665
              dicarboxylic acid metabolic process 75
                10-formyltetrahydrofolate metabolic process + 3
                2-oxoglutarate metabolic process + 16
                5,6,7,8-tetrahydromethanopterin metabolic process + 0
                Kdo2-lipid A metabolic process + 0
                actinorhodin metabolic process + 0
                aldaric acid metabolic process + 0
                aspartate metabolic process + 6
                chorismate metabolic process + 0
                diaminopimelate metabolic process + 0
                dicarboxylic acid biosynthetic process + 12
                dicarboxylic acid catabolic process + 11
                dihydrofolate metabolic process + 2
                folic acid metabolic process + 4
                fumarate metabolic process + 3
                gibberellin 12 metabolic process + 0
                glutamate metabolic process + 25
                malate metabolic process 7
                oxalate metabolic process + 1
                oxaloacetate metabolic process + 10
                prephenate(2-) metabolic process + 0
                protocatechuate catabolic process, ortho-cleavage 0
                quinolinate metabolic process + 5
                succinate metabolic process + 6
paths to the root