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ONTOLOGY REPORT - ANNOTATIONS


Term:inositol phosphate metabolic process
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Accession:GO:0043647 term browser browse the term
Definition:The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
Synonyms:exact_synonym: inositol phosphate metabolism
 narrow_synonym: myo-inositol phosphate metabolic process;   myo-inositol phosphate metabolism



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inositol phosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galr2 galanin receptor 2 IDA RGD PMID:9427506 RGD:69840 NCBI chr10:101,513,689...101,517,176
Ensembl chr10:101,514,471...101,517,176
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IMP RGD PMID:17573483 RGD:5685371 NCBI chr12:43,624,778...43,735,375
Ensembl chr12:43,624,897...43,731,262
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEP RGD PMID:1331748 RGD:9727450 NCBI chr 9:86,735,793...86,756,640
Ensembl chr 9:86,742,102...86,755,108
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in ISO
ISS
(PMID:30624931)
GO_REF:0000024
RGD
UniProt
PMID:30624931 GO_REF:0000024 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
diphosphoinositol polyphosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt3 nudix hydrolase 3 involved_in ISO
ISS
(PMID:10585413)
GO_REF:0000024
RGD
UniProt
PMID:10585413 GO_REF:0000024 NCBI chr20:5,634,345...5,686,950
Ensembl chr20:5,634,349...5,686,874
JBrowse link
diphosphoinositol polyphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt11 nudix hydrolase 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:16,326,775...16,333,396
Ensembl chr  X:16,326,598...16,333,145
JBrowse link
G Nudt3 nudix hydrolase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:5,634,345...5,686,950
Ensembl chr20:5,634,349...5,686,874
JBrowse link
G Nudt4 nudix hydrolase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:30,188,100...30,204,620
Ensembl chr 7:30,188,100...30,204,615
JBrowse link
inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:20011604) RGD PMID:20011604 NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221
JBrowse link
G Ip6k1 inositol hexakisphosphate kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:108,693,068...108,737,278 JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:109,483,843...109,510,172
Ensembl chr 8:109,484,310...109,510,166
JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:11502751)
RGD PMID:11502751 PMID:21873635 RGD:13792537 NCBI chr20:5,223,863...5,245,443
Ensembl chr20:5,224,120...5,245,428
JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3583918 (MGI:3583505|PMID:15939867)
RGD PMID:15939867 PMID:21873635 MGI:3583505, RGD:13792537 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705
JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:15,190,191...15,235,203
Ensembl chr17:15,190,265...15,229,541
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004
JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:82,500,957...82,522,533
Ensembl chr 1:82,500,957...82,522,779
JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:108,284,120...108,327,683
Ensembl chr 3:108,284,120...108,323,428
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:98,315,280...98,394,537
Ensembl chr 9:98,315,252...98,390,814
JBrowse link
inositol phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:15707678 RGD:9743914 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
inositol phosphate dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:96,865,634...96,893,506
Ensembl chr13:96,868,580...96,893,503
JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 5:17,775,684...17,802,570
Ensembl chr 5:17,772,608...17,802,570
JBrowse link
G Impa1 inositol monophosphatase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
IDA
PMID:21873635
(PMID:17068342)
GO_REF:0000107
(PMID:9462881)
RGD
Ensembl
PMID:9462881 PMID:17068342 PMID:21873635 PMID:9462881 GO_REF:0000107, RGD:13792537, RGD:2302240 NCBI chr 2:91,462,781...91,484,057
Ensembl chr 2:91,462,799...91,484,313
JBrowse link
G Impa2 inositol monophosphatase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000002
(PMID:17068342)
PMID:21873635
InterPro
RGD
PMID:17068342 PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr18:60,834,206...60,867,575
Ensembl chr18:60,834,246...60,865,641
JBrowse link
G Inpp1 inositol polyphosphate-1-phosphatase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:48,688,037...48,717,793
Ensembl chr 9:48,669,901...48,717,793
JBrowse link
G Inpp4b inositol polyphosphate-4-phosphatase type II B acts_upstream_of_or_within IDA PMID:9295334 MGI PMID:9295334 RGD:633135 NCBI chr19:25,920,189...26,670,085
Ensembl chr19:25,925,358...26,280,634
JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:8006039)
RGD PMID:8006039 PMID:21873635 PMID:21873635 RGD:13792537, RGD:13792537 NCBI chr 1:194,190,086...194,380,429
Ensembl chr 1:194,190,393...194,380,428
JBrowse link
G Inpp5b inositol polyphosphate-5-phosphatase B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:136,996,766...137,061,315
Ensembl chr 5:136,996,686...137,061,315
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E acts_upstream_of_or_within ISO (MGI:1861829|PMID:10806194) RGD PMID:10806194 MGI:1861829 NCBI chr 3:9,216,776...9,229,539
Ensembl chr 3:9,216,776...9,229,450
JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:78,374,161...78,385,305
Ensembl chr14:78,374,161...78,385,326
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:12536145)
RGD PMID:12536145 PMID:21873635 RGD:13792537 NCBI chr10:60,474,262...60,495,813
Ensembl chr10:60,475,897...60,496,773
JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO (MGI:3619505|PMID:16399794) RGD PMID:16399794 MGI:3619505 NCBI chr 8:10,617,993...10,670,724
Ensembl chr 8:10,617,993...10,668,172
JBrowse link
G Mtmr7 myotubularin related protein 7 acts_upstream_of_or_within ISO (MGI:2673068|PMID:12890864) RGD PMID:12890864 MGI:2673068 NCBI chr16:51,641,225...51,732,212
Ensembl chr16:51,641,190...51,732,182
JBrowse link
G Ocrl OCRL, inositol polyphosphate-5-phosphatase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:127,089,508...127,140,362
Ensembl chr  X:127,089,590...127,140,362
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO
IDA
(PMID:9593664) RGD PMID:9593664 PMID:18056380 RGD:2292524 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Synj1 synaptojanin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2179801 (MGI:1346710|PMID:10535736)
RGD PMID:10535736 PMID:21873635 MGI:1346710, RGD:13792537 NCBI chr11:30,192,629...30,269,277
Ensembl chr11:30,192,629...30,269,220
JBrowse link
G Synj2 synaptojanin 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:9388224 PMID:21873635 RGD:69390, RGD:13792537 NCBI chr 1:46,518,594...46,621,919
Ensembl chr 1:46,518,709...46,633,687
JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:16973916 RGD:2299886 NCBI chr 3:149,385,587...149,416,330
Ensembl chr 3:149,385,587...149,416,330
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:85738|PMID:9013981)
Ensembl
RGD
PMID:9013981 GO_REF:0000107 MGI:85738 NCBI chr19:45,547,416...45,683,930
Ensembl chr19:45,547,416...45,683,930
JBrowse link
G Ptafr platelet-activating factor receptor acts_upstream_of_or_within ISO (MGI:85738|PMID:9013981) RGD PMID:9013981 MGI:85738 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:12641450) RGD PMID:12641450 NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
JBrowse link
inositol trisphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inppl1 inositol polyphosphate phosphatase-like 1 IDA RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in ISO (PMID:30624931) RGD PMID:30624931 NCBI chr20:17,216,988...17,251,675
Ensembl chr20:17,218,037...17,251,705
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:121,710,750...121,844,501
Ensembl chr 6:121,710,755...121,844,107
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in ISS
ISO
GO_REF:0000024
(PMID:1654894)
UniProt
RGD
PMID:1654894 GO_REF:0000024 NCBI chr13:92,069,160...92,164,281
Ensembl chr13:92,069,216...92,162,004
JBrowse link
G Plcb1 phospholipase C beta 1 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 3:122,059,968...122,772,896
Ensembl chr 3:122,060,031...122,772,869
JBrowse link
G Plcb3 phospholipase C beta 3 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 1:204,143,257...204,160,384
Ensembl chr 1:204,144,956...204,160,228
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) RGD PMID:7559487 PMID:7782310 NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:228,409,883...229,638,794
Ensembl chr 1:228,408,947...229,639,080
JBrowse link
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1r1 ADCYAP receptor type I IDA RGD PMID:8943280 RGD:2315982 NCBI chr 4:84,593,558...84,642,700
Ensembl chr 4:84,593,892...84,642,700
JBrowse link
G Avpr1b arginine vasopressin receptor 1B involved_in ISO (PMID:9322919) RGD PMID:9322919 NCBI chr13:43,046,960...43,057,110
Ensembl chr13:43,046,267...43,057,792
JBrowse link
G Cd244 CD244 molecule involved_in ISO (PMID:8376943) RGD PMID:8376943 NCBI chr13:84,018,887...84,036,612
Ensembl chr13:84,020,095...84,036,100
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IDA RGD PMID:1332507 RGD:2316794 NCBI chr 1:47,879,956...47,911,500
Ensembl chr 1:47,880,309...47,911,709
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:11861328 RGD:9743897 NCBI chr 3:167,606,215...167,656,377
Ensembl chr 3:167,606,215...167,656,377
JBrowse link
G Ptafr platelet-activating factor receptor IDA RGD PMID:8798508 RGD:9999203 NCBI chr 5:144,765,770...144,795,057
Ensembl chr 5:144,765,976...144,795,251
JBrowse link
G Pth parathyroid hormone involved_in ISO (PMID:11604398) RGD PMID:11604398 NCBI chr 1:167,508,121...167,511,530
Ensembl chr 1:167,508,598...167,511,530
JBrowse link
G Pth1r parathyroid hormone 1 receptor involved_in IDA PMID:19608645 BHF-UCL PMID:19608645 RGD:8553376 NCBI chr 8:110,693,910...110,725,458
Ensembl chr 8:110,697,485...110,719,729
JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:15641770) RGD PMID:15641770 NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262
JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15705806)
UniProt
Ensembl
RGD
PMID:15705806 GO_REF:0000024 GO_REF:0000107 NCBI chr12:15,217,217...15,222,679
Ensembl chr12:15,217,442...15,221,889
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in IEA
ISO
GO_REF:0000107
(MGI:5318037|PMID:10493819)
Ensembl
RGD
PMID:10493819 GO_REF:0000107 MGI:5318037 NCBI chr 6:5,661,871...5,728,109
Ensembl chr 6:5,661,871...5,724,521
JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457
JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IDA PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 2:145,241,975...145,248,186
Ensembl chr 2:145,241,849...145,248,457
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:8670200) RGD PMID:8670200 NCBI chr 1:155,295,110...155,330,610
Ensembl chr 1:155,295,111...155,330,808
JBrowse link
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:16709602 RGD:2300424 NCBI chr 8:118,795,196...118,818,186
Ensembl chr 8:118,795,201...118,818,186
JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024|MGI:1856025 (MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:2135699 NCBI chr11:3,316,818...3,334,804
Ensembl chr11:3,317,058...3,334,801
JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:3583523|PMID:12960403)
UniProt
RGD
PMID:12960403 GO_REF:0000024 MGI:3583523 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      organic substance metabolic process 11568
        organophosphate metabolic process 953
          inositol phosphate metabolic process 60
            diphosphoinositol polyphosphate metabolic process + 3
            inositol phosphate biosynthetic process + 33
            inositol phosphate catabolic process + 19
            inositol trisphosphate metabolic process + 18
            myo-inositol hexakisphosphate metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      organic substance metabolic process 11568
        organic hydroxy compound metabolic process 567
          alcohol metabolic process 374
            polyol metabolic process 125
              inositol phosphate metabolic process 60
                diphosphoinositol polyphosphate metabolic process + 3
                inositol phosphate biosynthetic process + 33
                inositol phosphate catabolic process + 19
                inositol trisphosphate metabolic process + 18
                myo-inositol hexakisphosphate metabolic process + 0
paths to the root