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ONTOLOGY REPORT - ANNOTATIONS


Term:inositol phosphate metabolic process
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Accession:GO:0043647 term browser browse the term
Definition:The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
Synonyms:exact_synonym: inositol phosphate metabolism
 narrow_synonym: myo-inositol phosphate metabolic process;   myo-inositol phosphate metabolism


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inositol phosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Galr2 galanin receptor 2 IDA RGD PMID:9427506 RGD:69840 NCBI chr10:105,156,793...105,159,221
Ensembl chr10:105,156,632...105,237,611
JBrowse link
G Grk3 G protein-coupled receptor kinase 3 IMP RGD PMID:17573483 RGD:5685371 NCBI chr12:49,626,871...49,750,389
Ensembl chr12:49,626,871...49,746,272
JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B IEP RGD PMID:1331748 RGD:9727450 NCBI chr 9:93,112,781...93,130,135
Ensembl chr 9:93,112,805...93,125,014
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in ISO
ISS
(PMID:30624931)
GO_REF:0000024
RGD
UniProt
PMID:30624931 GO_REF:0000024 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
diphosphoinositol polyphosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt3 nudix hydrolase 3 involved_in ISO
ISS
(PMID:10585413)
GO_REF:0000024
RGD
UniProt
PMID:10585413 GO_REF:0000024 NCBI chr20:7,155,744...7,208,292
Ensembl chr20:7,155,748...7,208,292
JBrowse link
diphosphoinositol polyphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nudt10 nudix hydrolase 10 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:17,540,036...17,541,296
Ensembl chr  X:17,540,458...17,540,952
Ensembl chr  X:17,540,458...17,540,952
JBrowse link
G Nudt11 nudix hydrolase 11 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:17,171,510...17,215,108
Ensembl chr  X:17,540,458...17,540,952
Ensembl chr  X:17,540,458...17,540,952
JBrowse link
G Nudt3 nudix hydrolase 3 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr20:7,155,744...7,208,292
Ensembl chr20:7,155,748...7,208,292
JBrowse link
G Nudt4 nudix hydrolase 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:36,643,916...36,660,334
Ensembl chr 7:36,643,916...36,660,141
JBrowse link
inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgf2 fibroblast growth factor 2 involved_in ISO (PMID:20011604) RGD PMID:20011604 NCBI chr 2:124,081,072...124,134,133
Ensembl chr 2:124,081,072...124,134,681
JBrowse link
G Ip6k1 inositol hexakisphosphate kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:116,781,957...116,826,152
Ensembl chr 8:116,804,451...116,823,540
JBrowse link
G Ip6k2 inositol hexakisphosphate kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 8:117,574,136...117,599,849
Ensembl chr 8:117,574,161...117,599,848
JBrowse link
G Ip6k3 inositol hexakisphosphate kinase 3 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:11502751)
RGD PMID:11502751, PMID:21873635 RGD:13792537 NCBI chr20:5,733,485...5,754,859
Ensembl chr20:5,733,482...5,754,773
JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:3583918 (MGI:3583505|PMID:15939867)
RGD PMID:15939867, PMID:21873635 MGI:3583505, RGD:13792537 NCBI chr20:18,457,309...18,489,884
Ensembl chr20:18,457,310...18,489,833
JBrowse link
G Ippk inositol-pentakisphosphate 2-kinase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:15,604,148...15,643,312
Ensembl chr17:15,604,145...15,643,489
JBrowse link
G Itpka inositol-trisphosphate 3-kinase A involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:111,545,007...111,553,605
Ensembl chr 3:111,545,007...111,553,604
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:98,615,287...98,710,426
Ensembl chr13:98,615,287...98,708,149
JBrowse link
G Itpkc inositol-trisphosphate 3-kinase C involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:84,018,857...84,040,433
Ensembl chr 1:84,018,859...84,040,433
JBrowse link
G Ppip5k1 diphosphoinositol pentakisphosphate kinase 1 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:113,272,850...113,316,324
Ensembl chr 3:113,272,850...113,445,435
JBrowse link
G Ppip5k2 diphosphoinositol pentakisphosphate kinase 2 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:111,232,967...111,249,613
Ensembl chr 9:111,220,858...111,286,185
JBrowse link
inositol phosphate catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:15707678 RGD:9743914 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
inositol phosphate dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bpnt1 3'(2'), 5'-bisphosphate nucleotidase 1 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr13:103,268,045...103,292,848
Ensembl chr13:103,268,068...103,292,854
JBrowse link
G Bpnt2 3'(2'), 5'-bisphosphate nucleotidase 2 involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr17:90,191,119...90,218,013
Ensembl chr17:90,188,043...90,218,013
Ensembl chr 5:90,188,043...90,218,013
JBrowse link
G Impa1 inositol monophosphatase 1 involved_in
acts_upstream_of_or_within
IBA
ISO
IEA
IDA
PMID:21873635
(PMID:17068342)
GO_REF:0000107
(PMID:9462881)
RGD
Ensembl
PMID:9462881 PMID:17068342, PMID:21873635, PMID:9462881 GO_REF:0000107, RGD:13792537, RGD:2302240 NCBI chr 2:93,675,203...93,696,355
Ensembl chr 2:93,675,203...93,696,232
JBrowse link
G Impa2 inositol monophosphatase 2 involved_in
acts_upstream_of_or_within
IEA
ISO
IBA
GO_REF:0000002
(PMID:17068342)
PMID:21873635
InterPro
RGD
PMID:17068342, PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr18:63,016,577...63,050,123
Ensembl chr18:63,016,577...63,047,781
JBrowse link
G Inpp1 inositol polyphosphate-1-phosphatase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:53,544,602...53,574,303
Ensembl chr 9:53,546,018...53,574,690
JBrowse link
G Inpp5a inositol polyphosphate-5-phosphatase A involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:8006039)
RGD PMID:8006039, PMID:21873635 RGD:13792537 NCBI chr 1:211,732,163...211,920,844
Ensembl chr 1:211,732,713...211,921,099
JBrowse link
G Inpp5b inositol polyphosphate-5-phosphatase B involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:142,731,767...142,796,305
Ensembl chr 5:142,731,767...142,796,305
JBrowse link
G Inpp5e inositol polyphosphate-5-phosphatase E acts_upstream_of_or_within ISO (MGI:1861829|PMID:10806194) RGD PMID:10806194 MGI:1861829 NCBI chr 3:3,843,307...3,856,154
Ensembl chr 3:3,843,307...3,855,981
JBrowse link
G Inpp5j inositol polyphosphate-5-phosphatase J involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:83,730,861...83,742,016
Ensembl chr14:83,730,862...83,741,969
JBrowse link
G Inpp5k inositol polyphosphate-5-phosphatase K involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
(PMID:12536145)
RGD PMID:12536145, PMID:21873635 RGD:13792537 NCBI chr10:63,775,639...63,796,879
Ensembl chr10:63,776,378...63,795,899
JBrowse link
G Mtmr2 myotubularin related protein 2 acts_upstream_of_or_within ISO (MGI:3619505|PMID:16399794) RGD PMID:16399794 MGI:3619505 NCBI chr 8:12,283,471...12,334,014
Ensembl chr 8:12,284,528...12,333,316
JBrowse link
G Mtmr7 myotubularin related protein 7 acts_upstream_of_or_within ISO (MGI:2673068|PMID:12890864) RGD PMID:12890864 MGI:2673068 NCBI chr16:54,765,214...54,856,255
Ensembl chr16:54,765,325...54,856,225
JBrowse link
G Ocrl OCRL, inositol polyphosphate-5-phosphatase involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:134,742,226...134,793,411
Ensembl chr  X:134,742,356...134,792,618
JBrowse link
G Pten phosphatase and tensin homolog involved_in ISO (PMID:9593664) RGD PMID:9593664 NCBI chr 1:251,421,814...251,487,634
Ensembl chr 1:251,421,596...251,487,832
JBrowse link
G Synj1 synaptojanin 1 involved_in
acts_upstream_of_or_within
IBA
ISO
PMID:21873635
MGI:2179801 (MGI:1346710|PMID:10535736)
RGD PMID:10535736, PMID:21873635 MGI:1346710, RGD:13792537 NCBI chr11:31,105,784...31,181,573
Ensembl chr11:31,104,787...31,180,642
JBrowse link
G Synj2 synaptojanin 2 involved_in IDA
IBA
PMID:21873635 RGD
GO_Central
PMID:9388224, PMID:21873635 RGD:69390, RGD:13792537 NCBI chr 1:46,835,922...46,932,544
Ensembl chr 1:46,835,971...46,932,529
JBrowse link
inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plcg1 phospholipase C, gamma 1 IMP RGD PMID:16973916 RGD:2299886 NCBI chr 3:156,727,642...156,758,307
Ensembl chr 3:156,727,642...156,758,307
JBrowse link
G Plcg2 phospholipase C, gamma 2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(MGI:85738|PMID:9013981)
Ensembl
RGD
PMID:9013981 GO_REF:0000107 MGI:85738 NCBI chr19:50,039,410...50,173,543
Ensembl chr19:50,045,020...50,173,220
JBrowse link
G Ptafr platelet-activating factor receptor acts_upstream_of_or_within ISO (MGI:85738|PMID:9013981) RGD PMID:9013981 MGI:85738 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Scp2 sterol carrier protein 2 involved_in ISO (PMID:12641450) RGD PMID:12641450 NCBI chr 5:127,647,934...127,735,703
Ensembl chr 5:127,620,274...127,735,739
JBrowse link
inositol trisphosphate metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Inppl1 inositol polyphosphate phosphatase-like 1 IDA RGD PMID:12933696 RGD:1626126 NCBI chr 1:166,898,177...166,912,524
Ensembl chr 1:166,899,894...166,912,524
JBrowse link
G Ipmk inositol polyphosphate multikinase involved_in ISO (PMID:30624931) RGD PMID:30624931 NCBI chr20:18,457,309...18,489,884
Ensembl chr20:18,457,310...18,489,833
JBrowse link
G Itpk1 inositol-tetrakisphosphate 1-kinase involved_in IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr 6:126,448,920...126,582,188
Ensembl chr 6:126,450,139...126,582,134
JBrowse link
G Itpkb inositol-trisphosphate 3-kinase B involved_in ISS
ISO
GO_REF:0000024
(PMID:1654894)
UniProt
RGD
PMID:1654894 GO_REF:0000024 NCBI chr13:98,615,287...98,710,426
Ensembl chr13:98,615,287...98,708,149
JBrowse link
G Plcb1 phospholipase C beta 1 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 3:127,721,244...128,419,565
Ensembl chr 3:128,155,069...128,419,545
JBrowse link
G Plcb3 phospholipase C beta 3 IDA RGD PMID:8387502 RGD:11535163 NCBI chr 1:222,207,887...222,224,993
Ensembl chr 1:222,209,575...222,224,910
JBrowse link
negative regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plek pleckstrin involved_in ISO (PMID:7559487), (PMID:7782310) RGD PMID:7559487 PMID:7782310 NCBI chr14:100,151,518...100,184,192
Ensembl chr14:100,151,210...100,217,913
JBrowse link
G Prkg1 protein kinase cGMP-dependent 1 IMP RGD PMID:7535379 RGD:7777104 NCBI chr 1:248,982,039...250,300,952 JBrowse link
positive regulation of inositol phosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1r1 ADCYAP receptor type I IDA RGD PMID:8943280 RGD:2315982 NCBI chr 4:85,662,809...85,711,696
Ensembl chr 4:85,662,892...85,711,696
JBrowse link
G Avpr1b arginine vasopressin receptor 1B involved_in ISO (PMID:9322919) RGD PMID:9322919 NCBI chr13:48,367,307...48,378,831
Ensembl chr13:48,367,307...48,378,831
JBrowse link
G Cd244 CD244 molecule involved_in ISO (PMID:8376943) RGD PMID:8376943 NCBI chr13:89,959,091...89,995,993
Ensembl chr13:89,975,267...89,995,974
JBrowse link
G Mas1 MAS1 proto-oncogene, G protein-coupled receptor IDA RGD PMID:1332507 RGD:2316794 NCBI chr 1:48,076,761...48,108,218
Ensembl chr 1:48,077,033...48,108,216
JBrowse link
G Ntsr1 neurotensin receptor 1 IMP RGD PMID:11861328 RGD:9743897 NCBI chr 3:175,982,313...176,046,345
Ensembl chr 3:175,885,894...176,046,345
JBrowse link
G Ptafr platelet-activating factor receptor IDA RGD PMID:8798508 RGD:9999203 NCBI chr 5:150,746,284...150,775,675
Ensembl chr 5:150,754,021...150,775,672
JBrowse link
G Pth parathyroid hormone involved_in ISO (PMID:11604398) RGD PMID:11604398 NCBI chr 1:178,215,829...178,218,761
Ensembl chr 1:178,215,829...178,218,761
JBrowse link
G Pth1r parathyroid hormone 1 receptor involved_in IDA PMID:19608645 BHF-UCL PMID:19608645 RGD:8553376 NCBI chr 8:118,984,531...119,012,803
Ensembl chr 8:118,988,053...119,012,671
JBrowse link
G Snca synuclein alpha involved_in ISO (PMID:15641770) RGD PMID:15641770 NCBI chr 4:90,782,412...90,883,236
Ensembl chr 4:90,782,374...90,882,285
JBrowse link
positive regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 involved_in ISS
IEA
ISO
GO_REF:0000024
GO_REF:0000107
(PMID:15705806)
UniProt
Ensembl
RGD
PMID:15705806 GO_REF:0000024 GO_REF:0000107 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Lhcgr luteinizing hormone/choriogonadotropin receptor involved_in IEA
ISO
GO_REF:0000107
(MGI:5318037|PMID:10493819)
Ensembl
RGD
PMID:10493819 GO_REF:0000107 MGI:5318037 NCBI chr 6:12,493,182...12,554,482
Ensembl chr 6:12,493,943...12,554,439
JBrowse link
G Myh9 myosin, heavy chain 9 IMP RGD PMID:20068007 RGD:6902910 NCBI chr 7:118,740,005...118,792,507
Ensembl chr 7:118,741,110...118,792,625
JBrowse link
G P2ry1 purinergic receptor P2Y1 involved_in IDA PMID:11390975 BHF-UCL PMID:11390975 RGD:8553380 NCBI chr 2:151,314,818...151,320,312
Ensembl chr 2:151,314,818...151,320,319
JBrowse link
G P2ry6 pyrimidinergic receptor P2Y6 involved_in ISO (PMID:8670200) RGD PMID:8670200 NCBI chr 1:165,972,439...166,008,348
Ensembl chr 1:165,972,440...165,997,751
JBrowse link
G Plcd1 phospholipase C, delta 1 IMP RGD PMID:16709602 RGD:2300424 NCBI chr 8:127,753,514...127,782,070
Ensembl chr 8:127,753,539...127,782,070
JBrowse link
G Pou1f1 POU class 1 homeobox 1 acts_upstream_of_or_within ISO MGI:1856024|MGI:1856025 (MGI:2135699|PMID:11371619) RGD PMID:11371619 MGI:2135699 NCBI chr11:2,645,659...2,662,581
Ensembl chr11:2,645,865...2,662,579
JBrowse link
regulation of inositol trisphosphate biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ptk2b protein tyrosine kinase 2 beta involved_in ISS
ISO
GO_REF:0000024
(MGI:3583523|PMID:12960403)
UniProt
RGD
PMID:12960403 GO_REF:0000024 MGI:3583523 NCBI chr15:42,827,306...42,947,796
Ensembl chr15:42,827,310...42,947,656
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      organic substance metabolic process 11392
        organophosphate metabolic process 934
          inositol phosphate metabolic process 60
            diphosphoinositol polyphosphate metabolic process + 4
            inositol phosphate biosynthetic process + 33
            inositol phosphate catabolic process + 18
            inositol trisphosphate metabolic process + 18
            myo-inositol hexakisphosphate metabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19599
    metabolic process 11860
      organic substance metabolic process 11392
        organic hydroxy compound metabolic process 550
          alcohol metabolic process 362
            polyol metabolic process 122
              inositol phosphate metabolic process 60
                diphosphoinositol polyphosphate metabolic process + 4
                inositol phosphate biosynthetic process + 33
                inositol phosphate catabolic process + 18
                inositol trisphosphate metabolic process + 18
                myo-inositol hexakisphosphate metabolic process + 0
paths to the root