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ONTOLOGY REPORT - ANNOTATIONS

Term:RNA polyadenylation
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Accession:GO:0043631 term browser browse the term
Definition:The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.

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RNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Papola poly (A) polymerase alpha ISO (MGI:MGI:5004778|PMID:18084034) RGD PMID:18084034 MGI:MGI:5004778 NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531 		JBrowse link
G Papolg poly(A) polymerase gamma ISO (PMID:11287430), (PMID:11463842) RGD PMID:11287430, PMID:11463842 NCBI chr14:108,624,359...108,658,371
Ensembl chr14:108,624,359...108,658,371 		JBrowse link
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 ISO (PMID:18083836) RGD PMID:18083836 NCBI chr14:113,530,470...113,561,645
Ensembl chr14:113,530,470...113,561,645 		JBrowse link
G Tent2 terminal nucleotidyltransferase 2 ISO
ISS		 (PMID:15070731)
GO_REF:0000024		 RGD
UniProt		 PMID:15070731 GO_REF:0000024 NCBI chr 2:22,746,290...22,798,252
Ensembl chr 2:22,747,547...22,798,214 		JBrowse link
mitochondrial mRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pnpt1 polyribonucleotide nucleotidyltransferase 1 ISO (PMID:18083837) RGD PMID:18083837 NCBI chr14:113,530,470...113,561,645
Ensembl chr14:113,530,470...113,561,645 		JBrowse link
mRNA alternative polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpsf6 cleavage and polyadenylation specific factor 6 ISO (PMID:20695905), (PMID:23187700), (PMID:29276085) RGD PMID:20695905, PMID:23187700, PMID:29276085 NCBI chr 7:60,385,688...60,417,661
Ensembl chr 7:60,385,688...60,416,925 		JBrowse link
G Cpsf7 cleavage and polyadenylation specific factor 7 ISS
ISO		 GO_REF:0000024
(PMID:29276085)		 UniProt
RGD		 PMID:29276085 GO_REF:0000024 NCBI chr 1:226,572,399...226,596,185
Ensembl chr 1:226,573,105...226,596,131 		JBrowse link
G Nudt21 nudix hydrolase 21 ISS
ISO		 GO_REF:0000024
(PMID:17098938), (PMID:20695905), (PMID:23187700), (PMID:29276085)		 UniProt
RGD		 PMID:17098938, PMID:20695905, PMID:23187700, PMID:29276085 GO_REF:0000024 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644 		JBrowse link
G Virma vir like m6A methyltransferase associated ISO (PMID:29507755) RGD PMID:29507755 NCBI chr 5:25,042,743...25,121,403
Ensembl chr 5:25,042,710...25,120,264 		JBrowse link
G Ythdc1 YTH domain containing 1 ISO (MGI:MGI:6161521|PMID:29799838) RGD PMID:29799838 MGI:MGI:6161521 NCBI chr14:22,971,834...23,002,326
Ensembl chr14:22,971,836...23,002,011 		JBrowse link
mRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahcyl1 adenosylhomocysteinase-like 1 ISO (MGI:MGI:3848108|PMID:19224921)
(PMID:19224921)		 RGD PMID:19224921 MGI:MGI:3848108 NCBI chr 2:210,438,884...210,474,350
Ensembl chr 2:210,438,893...210,473,761 		JBrowse link
G Aplp1 amyloid beta precursor like protein 1 ISO (MGI:MGI:3610697|PMID:16314516) RGD PMID:16314516 MGI:MGI:3610697 NCBI chr 1:88,897,525...88,908,750
Ensembl chr 1:88,897,532...88,908,750 		JBrowse link
G App amyloid beta precursor protein ISO
ISS		 (MGI:MGI:3610697|PMID:16314516)
GO_REF:0000024		 RGD
UniProt		 PMID:16314516 GO_REF:0000024, MGI:MGI:3610697 NCBI chr11:24,425,013...24,641,872
Ensembl chr11:24,425,005...24,641,858 		JBrowse link
G Cdc73 cell division cycle 73 ISO
IEA
ISS		 (PMID:21329879)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:21329879 GO_REF:0000024, GO_REF:0000107 NCBI chr13:60,403,771...60,496,511
Ensembl chr13:60,403,771...60,496,511 		JBrowse link
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:72,125,269...72,137,122
Ensembl chr 3:72,125,273...72,128,973 		JBrowse link
G Cpsf1 cleavage and polyadenylation specific factor 1 ISO
IBA		 (PMID:7590244)
PMID:21873635		 RGD PMID:7590244, PMID:21873635 RGD:13792537 NCBI chr 7:117,661,779...117,672,373
Ensembl chr 7:117,661,661...117,672,373 		JBrowse link
G Cpsf2 cleavage and polyadenylation specific factor 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:125,870,372...125,898,039
Ensembl chr 6:125,870,372...125,898,874 		JBrowse link
G Cpsf3 cleavage and polyadenylation specific factor 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:43,363,792...43,391,712
Ensembl chr 6:43,363,792...43,391,712 		JBrowse link
G Cstf2 cleavage stimulation factor subunit 2 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr  X:104,882,726...104,909,746
Ensembl chr  X:104,882,704...104,909,739 		JBrowse link
G Fip1l1 factor interacting with PAPOLA and CPSF1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:36,150,381...36,208,395
Ensembl chr14:36,150,399...36,208,373 		JBrowse link
G Leo1 LEO1 homolog, Paf1/RNA polymerase II complex component ISO
ISS		 (PMID:21329879)
GO_REF:0000024		 RGD
UniProt		 PMID:21329879 GO_REF:0000024 NCBI chr 8:82,380,906...82,405,293
Ensembl chr 8:82,380,757...82,405,644 		JBrowse link
G Mtpap mitochondrial poly(A) polymerase ISO
IBA		 (PMID:21292163)
PMID:21873635		 RGD PMID:21292163, PMID:21873635 RGD:13792537 NCBI chr17:56,046,507...56,068,185
Ensembl chr17:56,046,509...56,068,125 		JBrowse link
G Nudt21 nudix hydrolase 21 IEA GO_REF:0000002 InterPro GO_REF:0000002 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644 		JBrowse link
G Pabpc1l poly(A) binding protein, cytoplasmic 1-like ISO MGI:MGI:5437740 (MGI:MGI:5437387|PMID:22621333) RGD PMID:22621333 MGI:MGI:5437387 NCBI chr 3:160,410,733...160,447,073
Ensembl chr 3:160,410,757...160,444,940 		JBrowse link
G Paf1 PAF1 homolog, Paf1/RNA polymerase II complex component ISO
ISS		 (PMID:21329879)
GO_REF:0000024		 RGD
UniProt		 PMID:21329879 GO_REF:0000024 NCBI chr 1:85,362,421...85,367,999
Ensembl chr 1:85,362,268...85,368,031 		JBrowse link
G Papola poly (A) polymerase alpha ISO
IBA		 (PMID:19224921), (PMID:7590244)
PMID:21873635		 RGD PMID:7590244, PMID:19224921, PMID:21873635 RGD:13792537 NCBI chr 6:129,609,068...129,662,002
Ensembl chr 6:129,609,074...129,661,531 		JBrowse link
G Papolg poly(A) polymerase gamma IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:108,624,359...108,658,371
Ensembl chr14:108,624,359...108,658,371 		JBrowse link
G Pcf11 PCF11 cleavage and polyadenylation factor subunit IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:157,463,014...157,494,134
Ensembl chr 1:157,468,626...157,494,008 		JBrowse link
G Scaf8 SR-related CTD-associated factor 8 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:44,017,801...44,120,619
Ensembl chr 1:44,019,059...44,120,615 		JBrowse link
G Ssu72 SSU72 homolog, RNA polymerase II CTD phosphatase ISO
IBA
ISS		 (PMID:20861839)
PMID:21873635
GO_REF:0000024		 RGD
UniProt		 PMID:20861839, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 5:173,152,964...173,182,720
Ensembl chr 5:173,152,964...173,182,719 		JBrowse link
G Sympk symplekin ISO
IBA		 (PMID:20861839)
PMID:21873635		 RGD PMID:20861839, PMID:21873635 RGD:13792537 NCBI chr 1:79,931,097...79,959,461
Ensembl chr 1:79,931,156...79,959,461 		JBrowse link
G Tent2 terminal nucleotidyltransferase 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:22,746,290...22,798,252
Ensembl chr 2:22,747,547...22,798,214 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B ISO (PMID:28383716) RGD PMID:28383716 NCBI chr19:19,771,289...19,834,759
Ensembl chr19:19,771,677...19,832,812 		JBrowse link
G Tut1 terminal uridylyl transferase 1, U6 snRNA-specific ISS
IBA
ISO		 GO_REF:0000024
PMID:21873635
(PMID:18288197), (PMID:21102410)		 UniProt
RGD		 PMID:18288197, PMID:21102410, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 1:225,151,462...225,162,445
Ensembl chr 1:225,151,404...225,162,595 		JBrowse link
G Tut4 terminal uridylyl transferase 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:128,063,880...128,168,726
Ensembl chr 5:128,083,118...128,168,207 		JBrowse link
G Tut7 terminal uridylyl transferase 7 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:5,225,854...5,279,674
Ensembl chr17:5,225,835...5,271,794 		JBrowse link
G Wdr33 WD repeat domain 33 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr18:24,584,832...24,689,681
Ensembl chr18:24,584,900...24,689,636 		JBrowse link
ncRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tent4b terminal nucleotidyltransferase 4B ISO (PMID:25049417) RGD PMID:25049417 NCBI chr19:19,771,289...19,834,759
Ensembl chr19:19,771,677...19,832,812 		JBrowse link
ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tent4b terminal nucleotidyltransferase 4B ISO (PMID:26950371) RGD PMID:26950371 NCBI chr19:19,771,289...19,834,759
Ensembl chr19:19,771,677...19,832,812 		JBrowse link
negative regulation of mRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccnt1 cyclin T1 ISO (PMID:19575011) RGD PMID:19575011 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 ISO (PMID:19575011) RGD PMID:19575011 NCBI chr 3:11,742,269...11,747,117
Ensembl chr 3:11,742,266...11,747,113 		JBrowse link
G Ctr9 CTR9 homolog, Paf1/RNA polymerase II complex component ISO (PMID:19575011) RGD PMID:19575011 NCBI chr 1:175,839,140...175,869,167
Ensembl chr 1:175,839,108...175,869,165 		JBrowse link
G Nelfe negative elongation factor complex member E ISO (PMID:19575011) RGD PMID:19575011 NCBI chr20:4,530,328...4,536,085
Ensembl chr20:4,530,342...4,536,209 		JBrowse link
G Rnf20 ring finger protein 20 ISO (PMID:19575011) RGD PMID:19575011 NCBI chr 5:64,892,996...64,920,397
Ensembl chr 5:64,892,802...64,920,390 		JBrowse link
G Rnf40 ring finger protein 40 ISO (PMID:19575011) RGD PMID:19575011 NCBI chr 1:199,037,472...199,052,823
Ensembl chr 1:199,037,544...199,052,172 		JBrowse link
G Supt5h SPT5 homolog, DSIF elongation factor subunit ISO (PMID:19575011) RGD PMID:19575011 NCBI chr 1:85,437,780...85,466,854
Ensembl chr 1:85,437,780...85,466,854 		JBrowse link
G Zc3h14 zinc finger CCCH type containing 14 IBA
IEA		 PMID:21873635
GO_REF:0000002		 InterPro PMID:21873635 GO_REF:0000002, RGD:13792537 NCBI chr 6:122,729,834...122,767,462
Ensembl chr 6:122,729,874...122,767,462 		JBrowse link
positive regulation of mRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cpeb1 cytoplasmic polyadenylation element binding protein 1 ISO (PMID:28383716) RGD PMID:28383716 NCBI chr 1:143,171,457...143,278,485
Ensembl chr 1:143,171,264...143,278,485 		JBrowse link
G Cpeb3 cytoplasmic polyadenylation element binding protein 3 ISO (MGI:MGI:5300629|PMID:22153079) RGD PMID:22153079 MGI:MGI:5300629 NCBI chr 1:255,660,165...255,842,671
Ensembl chr 1:255,665,238...255,815,733 		JBrowse link
G Hsf1 heat shock transcription factor 1 ISO (PMID:14707147) RGD PMID:14707147 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478 		JBrowse link
G Nudt21 nudix hydrolase 21 ISS
ISO		 GO_REF:0000024
(PMID:15937220)		 UniProt
RGD		 PMID:15937220 GO_REF:0000024 NCBI chr19:11,451,366...11,470,637
Ensembl chr19:11,450,760...11,467,644 		JBrowse link
regulation of mRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ncbp1 nuclear cap binding protein subunit 1 NOT ISO
ISS		 (PMID:9342333)
GO_REF:0000024		 RGD
UniProt		 PMID:9342333 GO_REF:0000024 NCBI chr 5:61,734,118...61,767,098
Ensembl chr 5:61,734,118...61,766,481 		JBrowse link
G Ncbp2 nuclear cap binding protein subunit 2 NOT ISO (PMID:9342333) RGD PMID:9342333 NCBI chr11:72,071,838...72,103,087
Ensembl chr11:72,921,282...72,929,003 		JBrowse link
G Snrpa small nuclear ribonucleoprotein polypeptide A IMP RGD PMID:10521474 RGD:10755561 NCBI chr 1:83,999,670...84,008,429
Ensembl chr 1:83,999,671...84,008,293 		JBrowse link
G Zc3h3 zinc finger CCCH type containing 3 ISO (PMID:19364924) RGD PMID:19364924 NCBI chr 7:116,787,762...116,872,536
Ensembl chr 7:116,787,766...116,872,511 		JBrowse link
snoRNA polyadenylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tent4a terminal nucleotidyltransferase 4A IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:36,400,056...36,433,238
Ensembl chr 1:36,400,443...36,433,238 		JBrowse link
G Tent4b terminal nucleotidyltransferase 4B ISO
IBA		 (PMID:22442037)
PMID:21873635		 RGD PMID:22442037, PMID:21873635 RGD:13792537 NCBI chr19:19,771,289...19,834,759
Ensembl chr19:19,771,677...19,832,812 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      organic substance metabolic process 11651
        macromolecule metabolic process 10086
          nucleic acid metabolic process 4985
            RNA metabolic process 4469
              RNA polyadenylation 48
                RNA polyadenylation at postsynapse 0
                mRNA polyadenylation + 47
                ncRNA polyadenylation + 2
                polyadenylation of viral mRNA by polymerase stuttering 0
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA polyadenylation 48
                  RNA polyadenylation at postsynapse 0
                  mRNA polyadenylation + 47
                  ncRNA polyadenylation + 2
                  polyadenylation of viral mRNA by polymerase stuttering 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.