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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of transcription from RNA polymerase II promoter in response to stress
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Accession:GO:0043618 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).

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regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ino80 INO80 complex ATPase subunit involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 3:111,186,371...111,266,542
Ensembl chr 3:111,187,711...111,266,542 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Jun Jun proto-oncogene, AP-1 transcription factor subunit involved_in ISO (PMID:21113145) RGD PMID:21113145 NCBI chr 5:114,011,184...114,014,277
Ensembl chr 5:114,011,189...114,014,277 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO (PMID:16835242)
UniProtKB:O55033 (MGI:5613475|PMID:16835242)		 RGD PMID:16835242 MGI:5613475 NCBI chr 8:108,787,797...108,847,779
Ensembl chr 8:108,787,798...108,847,779 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO UniProtKB:Q99M51 (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr 9:50,246,767...50,373,307
Ensembl chr 9:50,247,692...50,373,284 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:5605960 NCBI chr 1:101,511,899...101,515,043
Ensembl chr 1:101,511,901...101,514,974 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 involved_in ISO (MGI:3840374|PMID:19328063) RGD PMID:19328063 MGI:3840374 NCBI chr 7:141,039,433...141,070,269
Ensembl chr 7:141,034,982...141,069,989 		JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 involved_in ISO (PMID:22735262) RGD PMID:22735262 NCBI chr 1:12,823,363...12,825,806
Ensembl chr 1:12,823,363...12,825,786 		JBrowse link
G Hif1an hypoxia inducible factor 1 subunit alpha inhibitor involved_in IBA
ISO		 PMID:21873635
(PMID:11641274)		 RGD PMID:11641274, PMID:21873635 RGD:13792537 NCBI chr 1:264,309,214...264,319,269
Ensembl chr 1:264,309,214...264,319,267 		JBrowse link
G Sirt2 sirtuin 2 involved_in ISO
ISS
IEA		 (PMID:24681946)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:24681946 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:86,948,866...86,971,954
Ensembl chr 1:86,948,918...86,971,952 		JBrowse link
G Vhl von Hippel-Lindau tumor suppressor involved_in ISO (PMID:11641274) RGD PMID:11641274 NCBI chr 4:145,580,869...145,587,835
Ensembl chr 4:145,580,799...145,587,845 		JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag3 BAG cochaperone 3 involved_in ISO (PMID:26159920) RGD PMID:26159920 NCBI chr 1:199,941,258...199,965,191
Ensembl chr 1:199,941,161...199,965,191 		JBrowse link
G Dnajb1 DnaJ heat shock protein family (Hsp40) member B1 involved_in ISO (PMID:9499401) RGD PMID:9499401 NCBI chr19:24,747,178...24,750,919
Ensembl chr19:24,747,178...24,750,919 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO
ISS		 (PMID:9499401)
GO_REF:0000024		 RGD
UniProt		 PMID:9499401 GO_REF:0000024 NCBI chr20:4,875,834...4,881,751
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO
ISS		 (PMID:9499401)
GO_REF:0000024		 RGD
UniProt		 PMID:9499401 GO_REF:0000024 NCBI chr20:4,877,638...4,880,112
Ensembl chr20:2,699,712...2,701,815 		JBrowse link
G Impact impact RWD domain protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5576818|PMID:24333428)		 UniProt
RGD		 PMID:24333428 GO_REF:0000024 MGI:5576818 NCBI chr18:4,325,872...4,346,734
Ensembl chr18:4,325,875...4,346,769 		JBrowse link
G LOC108348108 heat shock 70 kDa protein 1A involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr20:2,699,707...2,701,856
Ensembl chr20:4,877,324...4,879,779
Ensembl chr20:4,877,324...4,879,779 		JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 involved_in ISO (MGI:6101031|PMID:29149604) RGD PMID:29149604 MGI:6101031 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886 		JBrowse link
negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nedd4 NEDD4 E3 ubiquitin protein ligase involved_in ISO
IEA		 (PMID:17996703)
GO_REF:0000107		 RGD
Ensembl		 PMID:17996703 GO_REF:0000107 NCBI chr 8:79,323,408...79,408,842
Ensembl chr 8:79,323,408...79,408,833 		JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 involved_in ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632 		JBrowse link
G Atf4 activating transcription factor 4 involved_in ISO (PMID:12871976), (PMID:21113145)
(MGI:5433837|PMID:21113145), (MGI:5613480|PMID:12871976)		 RGD PMID:12871976 PMID:21113145 MGI:5433837 MGI:5613480 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Atf6 activating transcription factor 6 involved_in ISO (PMID:11163209), (PMID:11256944), (PMID:16469704) RGD PMID:11163209 PMID:11256944 PMID:16469704 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443 		JBrowse link
G Atf6b activating transcription factor 6 beta involved_in ISO (PMID:11256944) RGD PMID:11256944 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta involved_in ISO (PMID:15775988) RGD PMID:15775988 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910 		JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 involved_in IMP
ISO		 PMID:15665855
(MGI:5616321|PMID:15665855)		 RGD PMID:15665855, PMID:15665855 MGI:5616321, RGD:1558627 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283 		JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 involved_in ISO (PMID:16469704)
(MGI:5616319|PMID:16469704)		 RGD PMID:16469704 MGI:5616319 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 involved_in IBA
ISO
IEA
IDA		 PMID:21873635
(MGI:3525819|PMID:15601821)
GO_REF:0000107
PMID:8657121
UniProtKB:P17676 (PMID:15322075), (PMID:15775988), (PMID:22761832), (PMID:24939851)		 RGD
Ensembl		 PMID:15322075 PMID:15601821 PMID:15775988 PMID:22761832 PMID:24939851, PMID:21873635, PMID:8657121 GO_REF:0000107 MGI:3525819, RGD:13792537, RGD:1599740 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:3722921|PMID:14729979) RGD PMID:14729979 MGI:3722921 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694 		JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 involved_in ISO
IBA		 UniProtKB:O54862 (PMID:11163209)
PMID:21873635		 RGD PMID:11163209, PMID:21873635 RGD:13792537 NCBI chr  X:40,258,933...40,309,047
Ensembl chr  X:40,258,493...40,310,563 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (MGI:5621265|PMID:16407291) RGD PMID:16407291 MGI:5621265 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to heat stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsf1 heat shock transcription factor 1 involved_in ISO (PMID:10747973), (PMID:12659875), (PMID:12665592), (PMID:15016915), (PMID:25963659), (PMID:26754925), (PMID:7760831), (PMID:9499401) RGD PMID:7760831 PMID:9499401 PMID:10747973 PMID:12659875 PMID:12665592 PMID:15016915 PMID:25963659 PMID:26754925 NCBI chr 7:117,538,523...117,565,478
Ensembl chr 7:117,538,523...117,565,478 		JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hif1a hypoxia inducible factor 1 subunit alpha involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:19652095), (PMID:22735262), (PMID:24681946)		 UniProt
Ensembl
RGD		 PMID:19652095 PMID:22735262 PMID:24681946 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 involved_in ISO (PMID:24844779) RGD PMID:24844779 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Notch1 notch receptor 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5319604|PMID:18299578)		 UniProt
RGD		 PMID:18299578 GO_REF:0000024 MGI:5319604 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (PMID:23303788) RGD PMID:23303788 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450 		JBrowse link
G Tp53 tumor protein p53 acts_upstream_of_or_within ISO (MGI:4867601|PMID:20935145) RGD PMID:20935145 MGI:4867601 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
G Vegfa vascular endothelial growth factor A involved_in ISO (PMID:19652095) RGD PMID:19652095 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681 		JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf4 activating transcription factor 4 involved_in ISO
IMP		 (PMID:21113145)
PMID:23392669		 RGD PMID:21113145, PMID:23392669 RGD:10047168 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772 		JBrowse link
G Chd6 chromodomain helicase DNA binding protein 6 involved_in ISO
IEA
ISS		 (PMID:16314513)
GO_REF:0000107
GO_REF:0000024		 RGD
Ensembl
UniProt		 PMID:16314513 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:156,937,746...157,099,328
Ensembl chr 3:156,937,733...157,099,306 		JBrowse link
G Mt3 metallothionein 3 involved_in ISO
ISS		 (PMID:18554677)
GO_REF:0000024		 RGD
UniProt		 PMID:18554677 GO_REF:0000024 NCBI chr19:11,324,708...11,326,112
Ensembl chr19:11,324,698...11,326,139 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 involved_in IMP PMID:16314513 UniProt PMID:16314513 RGD:8655528 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:23274085) RGD PMID:23274085 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117 		JBrowse link
positive regulation of transcription from RNA polymerase II promoter in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gcn1 GCN1 activator of EIF2AK4 involved_in ISO (MGI:5576818|PMID:24333428) RGD PMID:24333428 MGI:5576818 NCBI chr12:46,728,684...46,789,696
Ensembl chr12:46,728,699...46,789,726 		JBrowse link
G Klf2 Kruppel-like factor 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr16:19,223,087...19,225,037
Ensembl chr16:19,223,087...19,225,037 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr10:47,768,592...47,775,130
Ensembl chr10:47,766,680...47,775,055
Ensembl chr10:47,766,680...47,775,055 		JBrowse link
G Muc1 mucin 1, cell surface associated involved_in ISO (PMID:15710329) RGD PMID:15710329 NCBI chr 2:188,543,137...188,547,874
Ensembl chr 2:188,543,137...188,547,874 		JBrowse link
G Nfe2l1 nuclear factor, erythroid 2-like 1 involved_in ISO (MGI:4820675|PMID:20385086), (MGI:6107583|PMID:11342101), (MGI:6316451|PMID:10601325) RGD PMID:10601325 PMID:11342101 PMID:20385086 MGI:4820675 MGI:6107583 MGI:6316451 NCBI chr10:84,686,762...84,699,313
Ensembl chr10:84,682,460...84,698,886 		JBrowse link
G Nfe2l2 nuclear factor, erythroid 2-like 2 involved_in ISO (PMID:23043106) RGD PMID:23043106 NCBI chr 3:62,497,568...62,525,146
Ensembl chr 3:62,497,571...62,524,996 		JBrowse link
G Tp53 tumor protein p53 involved_in ISO (PMID:30089260)
(MGI:5883206|PMID:22262176)		 RGD PMID:22262176 PMID:30089260 MGI:5883206 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
regulation of transcription from RNA polymerase II promoter in response to DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tp53 tumor protein p53 involved_in ISO (PMID:30089260) RGD PMID:30089260 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449 		JBrowse link
regulation of transcription from RNA polymerase II promoter in response to hypoxia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bach1 BTB domain and CNC homolog 1 involved_in ISO (PMID:12511571) RGD PMID:12511571 NCBI chr11:27,364,913...27,398,713
Ensembl chr11:27,364,916...27,398,842
Ensembl chr11:27,364,916...27,398,842 		JBrowse link
G Egr1 early growth response 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3847400|PMID:18323529)		 Ensembl
RGD		 PMID:18323529 GO_REF:0000107 MGI:3847400 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429 		JBrowse link
G Stox1 storkhead box 1 involved_in ISO (PMID:24738702) RGD PMID:24738702 NCBI chr20:32,276,857...32,353,677
Ensembl chr20:32,276,658...32,353,677 		JBrowse link
regulation of transcription from RNA polymerase II promoter in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ankrd2 ankyrin repeat domain 2 involved_in ISO (PMID:24434510) RGD PMID:24434510 NCBI chr 1:261,281,859...261,291,307
Ensembl chr 1:261,281,543...261,291,394 		JBrowse link
G Arnt aryl hydrocarbon receptor nuclear translocator involved_in IEA
ISO		 GO_REF:0000107
(PMID:8089148)		 Ensembl
RGD		 PMID:8089148 GO_REF:0000107 NCBI chr 2:196,594,178...196,651,486
Ensembl chr 2:196,594,303...196,651,179 		JBrowse link
G Epas1 endothelial PAS domain protein 1 involved_in
NOT|acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:106918 (MGI:2667513|PMID:12832481)
MGI:3710344 (MGI:2681387|PMID:14608355), (MGI:3703197|PMID:17284606)		 Ensembl
RGD		 PMID:12832481 PMID:14608355 PMID:17284606 GO_REF:0000107 MGI:2667513 MGI:2681387 MGI:3703197 NCBI chr 6:10,306,508...10,385,239
Ensembl chr 6:10,306,405...10,387,265 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha acts_upstream_of_or_within
involved_in		 IMP
ISO
IEA		 MGI:2385358 (MGI:2667513|PMID:12832481)
GO_REF:0000107
(PMID:8089148), (PMID:8387214)		 RGD
Ensembl		 PMID:8089148 PMID:8387214 PMID:12832481, PMID:18614764 GO_REF:0000107 MGI:2667513, RGD:2301848 NCBI chr 6:96,810,868...96,856,303
Ensembl chr 6:96,810,907...96,856,052 		JBrowse link
G Hmox1 heme oxygenase 1 involved_in IDA PMID:17430897 BHF-UCL PMID:17430897 RGD:8553479 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456 		JBrowse link
G Sin3a SIN3 transcription regulator family member A IDA RGD PMID:18945670 RGD:2306468 NCBI chr 8:61,748,590...61,803,314
Ensembl chr 8:61,762,768...61,803,099 		JBrowse link
regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Chek1 checkpoint kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5294291|PMID:18243098)		 UniProt
RGD		 PMID:18243098 GO_REF:0000024 MGI:5294291 NCBI chr 8:39,181,162...39,201,588
Ensembl chr 8:39,181,163...39,243,882 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19634
    response to stimulus 10423
      response to stress 4031
        cellular response to stress 1969
          regulation of DNA-templated transcription in response to stress 55
            regulation of transcription from RNA polymerase II promoter in response to stress 51
              negative regulation of transcription from RNA polymerase II promoter in response to stress + 16
              positive regulation of transcription from RNA polymerase II promoter in response to stress + 25
              regulation of transcription from RNA polymerase II promoter in response to DNA damage 1
              regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage + 2
              regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance + 0
              regulation of transcription from RNA polymerase II promoter in response to biotin starvation 0
              regulation of transcription from RNA polymerase II promoter in response to hypoxia + 13
              regulation of transcription from RNA polymerase II promoter in response to iron ion starvation + 0
              regulation of transcription from RNA polymerase II promoter in response to oxidative stress + 11
Path 2
Term Annotations click to browse term
  biological_process 19634
    metabolic process 11911
      cellular metabolic process 10866
        cellular aromatic compound metabolic process 5616
          nucleobase-containing compound metabolic process 5404
            nucleic acid metabolic process 4915
              RNA metabolic process 4400
                regulation of RNA metabolic process 3564
                  regulation of RNA biosynthetic process 3278
                    regulation of nucleic acid-templated transcription 3273
                      regulation of transcription, DNA-templated 3271
                        regulation of DNA-templated transcription in response to stress 55
                          regulation of transcription from RNA polymerase II promoter in response to stress 51
                            negative regulation of transcription from RNA polymerase II promoter in response to stress + 16
                            positive regulation of transcription from RNA polymerase II promoter in response to stress + 25
                            regulation of transcription from RNA polymerase II promoter in response to DNA damage 1
                            regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage + 2
                            regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance + 0
                            regulation of transcription from RNA polymerase II promoter in response to biotin starvation 0
                            regulation of transcription from RNA polymerase II promoter in response to hypoxia + 13
                            regulation of transcription from RNA polymerase II promoter in response to iron ion starvation + 0
                            regulation of transcription from RNA polymerase II promoter in response to oxidative stress + 11
paths to the root