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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of insulin-like growth factor receptor signaling pathway
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Accession:GO:0043569 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling.
Synonyms:exact_synonym: down regulation of insulin-like growth factor receptor signaling pathway;   downregulation of insulin-like growth factor receptor signaling pathway;   negative regulation of IGF receptor signaling pathway;   negative regulation of IGF receptor signalling pathway;   negative regulation of insulin-like growth factor receptor signalling pathway
 narrow_synonym: inhibition of insulin-like growth factor receptor signaling pathway


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negative regulation of insulin-like growth factor receptor signaling pathway term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atxn1 ataxin 1 acts_upstream_of_or_within ISO MGI:2429435 (MGI:3774689|PMID:18216249) RGD PMID:18216249 MGI:3774689 NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360
JBrowse link
G Atxn7 ataxin 7 acts_upstream_of_or_within ISO MGI:2651378 (MGI:3774689|PMID:18216249) RGD PMID:18216249 MGI:3774689 NCBI chr15:11,117,360...11,262,818
Ensembl chr15:11,118,886...11,263,106
JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in IEA
ISO
GO_REF:0000107
(PMID:19584291)
Ensembl
RGD
PMID:19584291 GO_REF:0000107 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
JBrowse link
G Bmp5 bone morphogenetic protein 5 involved_in ISO (PMID:19584291) RGD PMID:19584291 NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925
JBrowse link
G Cilp cartilage intermediate layer protein involved_in ISO (PMID:12746903) RGD PMID:12746903 NCBI chr 8:65,777,281...65,792,251
Ensembl chr 8:65,777,281...65,792,251
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 involved_in
acts_upstream_of_or_within
ISO (PMID:10766744)
(MGI:3589307|PMID:16024235)
RGD PMID:10766744 PMID:16024235 MGI:3589307 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Inppl1 inositol polyphosphate phosphatase-like 1 IMP RGD PMID:12933696 RGD:1626126 NCBI chr 1:156,183,043...156,197,500
Ensembl chr 1:156,183,059...156,197,500
JBrowse link
G Nkx3-1 NK3 homeobox 1 involved_in
acts_upstream_of_or_within
ISS
ISO
GO_REF:0000024
(MGI:3839214|PMID:19258508)
UniProt
RGD
PMID:19258508 GO_REF:0000024 MGI:3839214 NCBI chr15:44,473,851...44,476,443
Ensembl chr15:44,473,851...44,476,441
JBrowse link
G Trim72 tripartite motif containing 72 acts_upstream_of_or_within ISO MGI:96432 (MGI:5602876|PMID:23965929) RGD PMID:23965929 MGI:5602876 NCBI chr 1:182,613,753...182,621,613
Ensembl chr 1:182,613,712...182,621,606
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19492
    cellular process 18340
      signal transduction 6882
        negative regulation of signal transduction 1264
          negative regulation of insulin-like growth factor receptor signaling pathway 9
Path 2
Term Annotations click to browse term
  biological_process 19492
    biological regulation 13513
      regulation of biological process 12769
        regulation of cellular process 12228
          signal transduction 6882
            cell surface receptor signaling pathway 2779
              enzyme linked receptor protein signaling pathway 978
                transmembrane receptor protein tyrosine kinase signaling pathway 613
                  insulin-like growth factor receptor signaling pathway 40
                    regulation of insulin-like growth factor receptor signaling pathway 26
                      negative regulation of insulin-like growth factor receptor signaling pathway 9
paths to the root