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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of translational initiation in response to stress
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Accession:GO:0043558 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.
Synonyms:exact_synonym: regulation of translation initiation in response to stress


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regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 acts_upstream_of_or_within ISO (PMID:15937339) MGI PMID:15937339 NCBI chr 1:131,244,818...131,355,240
Ensembl chr 1:131,245,466...131,355,226 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15937339) Ensembl
MGI		 PMID:15937339 GO_REF:0000107 NCBI chr 7:91,085,025...91,109,835
Ensembl chr 7:91,085,335...91,109,827 		JBrowse link
negative regulation of cytoplasmic translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 1:131,244,818...131,355,240
Ensembl chr 1:131,245,466...131,355,226 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:65,230,145...65,299,084
Ensembl chr11:65,230,162...65,303,834 		JBrowse link
G NCK1 NCK adaptor protein 1 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr13:77,863,655...77,940,944
Ensembl chr13:77,863,701...77,945,468 		JBrowse link
G NCK2 NCK adaptor protein 2 involved_in IEA
IBA		 Ensembl
GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 3:49,063,813...49,222,274
Ensembl chr 3:49,063,991...49,198,664 		JBrowse link
G TMED2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within ISO (PMID:28797121) MGI PMID:28797121 NCBI chr14:29,390,903...29,400,454
Ensembl chr14:29,390,335...29,400,440 		JBrowse link
negative regulation of translation in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PML PML nuclear body scaffold involved_in ISO (PMID:16915281) UniProt PMID:16915281 NCBI chr 7:59,405,044...59,450,155
Ensembl chr 7:59,405,053...59,450,105 		JBrowse link
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:54,172,038...54,175,461
Ensembl chr 6:54,172,050...54,175,463 		JBrowse link
positive regulation of translation initiation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNAJC3 DnaJ heat shock protein family (Hsp40) member C3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:65,230,145...65,299,084
Ensembl chr11:65,230,162...65,303,834 		JBrowse link
positive regulation of translational initiation in response to starvation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (MGI:3589053|PMID:16121183)
(MGI:2149467|PMID:10655230)		 UniProt PMID:10655230 PMID:16121183 MGI:2149467 MGI:3589053 NCBI chr 1:131,244,818...131,355,240
Ensembl chr 1:131,245,466...131,355,226 		JBrowse link
regulation of cytoplasmic translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO (MGI:5576818|PMID:24333428) UniProt PMID:24333428 MGI:5576818 NCBI chr 1:131,244,818...131,355,240
Ensembl chr 1:131,245,466...131,355,226 		JBrowse link
G HRH4 histamine receptor H4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:109,302,264...109,318,607
Ensembl chr 6:109,303,820...109,319,479 		JBrowse link
G IMPACT impact RWD domain protein involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:109,235,590...109,272,801
Ensembl chr 6:109,235,585...109,272,793 		JBrowse link
regulation of eIF2 alpha phosphorylation by dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPM1 nucleophosmin 1 involved_in ISO (PMID:12882984) UniProt PMID:12882984 NCBI chr16:52,767,263...52,781,862
Ensembl chr16:52,765,298...52,781,771 		JBrowse link
regulation of eIF2 alpha phosphorylation by heme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15931390) Ensembl
MGI		 PMID:15931390 GO_REF:0000107 NCBI chr 3:5,075,026...5,113,390
Ensembl chr 3:5,075,054...5,113,622 		JBrowse link
G FECH ferrochelatase involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15931390) Ensembl
MGI		 PMID:15931390 GO_REF:0000107 NCBI chr 1:106,861,628...106,898,407
Ensembl chr 1:106,854,011...106,898,591 		JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:3582244|PMID:11106749) UniProt PMID:11106749 MGI:3582244 NCBI chr 3:57,423,894...57,506,247
Ensembl chr 3:57,423,943...57,506,245 		JBrowse link
G PPP1R15A protein phosphatase 1 regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) ParkinsonsUK-UCL PMID:11381086 MGI:5605960 NCBI chr 6:54,172,038...54,175,461
Ensembl chr 6:54,172,050...54,175,463 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      cellular metabolic process 8632
        translational initiation 131
          regulation of translational initiation 68
            regulation of translational initiation in response to stress 14
              negative regulation of translation in response to oxidative stress 1
              regulation of cytoplasmic translational initiation in response to stress + 3
              regulation of translation initiation in response to endoplasmic reticulum stress + 6
              regulation of translational initiation by eIF2 alpha dephosphorylation + 1
              regulation of translational initiation by eIF2 alpha phosphorylation + 9
              regulation of translational initiation in response to osmotic stress + 0
              regulation of translational initiation in response to starvation + 1
Path 2
Term Annotations click to browse term
  biological_process 17799
    biological regulation 12896
      regulation of biological process 12533
        regulation of metabolic process 6217
          regulation of biosynthetic process 5090
            regulation of cellular biosynthetic process 5003
              regulation of macromolecule biosynthetic process 4906
                regulation of gene expression 4791
                  post-transcriptional regulation of gene expression 735
                    regulation of translation 417
                      regulation of translational initiation 68
                        regulation of translational initiation in response to stress 14
                          negative regulation of translation in response to oxidative stress 1
                          regulation of cytoplasmic translational initiation in response to stress + 3
                          regulation of translation initiation in response to endoplasmic reticulum stress + 6
                          regulation of translational initiation by eIF2 alpha dephosphorylation + 1
                          regulation of translational initiation by eIF2 alpha phosphorylation + 9
                          regulation of translational initiation in response to osmotic stress + 0
                          regulation of translational initiation in response to starvation + 1
paths to the root