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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of translation in response to stress
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Accession:GO:0043555 term browser browse the term
Definition:Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
Synonyms:exact_synonym: translational stress response


show annotations for term's descendants           Sort by:
regulation of translation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Krt13 keratin 13 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6478935|PMID:32758484)		 UniProt
RGD		 PMID:32758484 GO_REF:0000024 MGI:6478935 NCBI chr10:85,052,122...85,056,032
Ensembl chr10:85,051,889...85,056,084 		JBrowse link
eiF2alpha phosphorylation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6467680|PMID:17707796)
(PMID:25329545)		 UniProt
RGD		 PMID:17707796 PMID:25329545 GO_REF:0000024 MGI:6467680 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISO
IEA		 (PMID:25329545)
GO_REF:0000107		 RGD
Ensembl		 PMID:25329545 GO_REF:0000107 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISO
ISS		 (PMID:22064321)
(MGI:5617428|PMID:25329545)
GO_REF:0000024		 RGD
UniProt		 PMID:22064321 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213), (PMID:16835242)
PMID:21873635
UniProtKB:O55033 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)		 RGD PMID:14676213 PMID:16835242 PMID:21873635 MGI:5613475 MGI:5613478, RGD:13792537 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 (PMID:16835242)
PMID:21873635
UniProtKB:Q99M51 (MGI:5613475|PMID:16835242), (MGI:5613478|PMID:14676213)		 RGD PMID:14676213 PMID:16835242 PMID:21873635 MGI:5613475 MGI:5613478, RGD:13792537 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B involved_in ISO (MGI:5613475|PMID:16835242) RGD PMID:16835242 MGI:5613475 NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737 		JBrowse link
G Tmed2 transmembrane p24 trafficking protein 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:4456438 (MGI:5914333|PMID:28797121)
GO_REF:0000107		 RGD
Ensembl		 PMID:28797121 GO_REF:0000107 MGI:5914333 NCBI chr12:32,052,542...32,061,596
Ensembl chr12:32,052,543...32,071,903 		JBrowse link
negative regulation of translation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:1333015|PMID:9930704) RGD PMID:9930704 MGI:1333015 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Map3k20 mitogen-activated protein kinase kinase kinase 20 involved_in ISO (PMID:32610081) RGD PMID:32610081 NCBI chr 3:57,128,561...57,289,943
Ensembl chr 3:57,130,551...57,289,626 		JBrowse link
G Sesn2 sestrin 2 involved_in ISO (PMID:24947615)
(MGI:5688277|PMID:24947615)		 RGD PMID:24947615 MGI:5688277 NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260 		JBrowse link
negative regulation of translation in response to oxidative stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pml PML nuclear body scaffold involved_in ISO (PMID:16915281) RGD PMID:16915281 NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971 		JBrowse link
negative regulation of translation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 IDA RGD PMID:9819435 RGD:70729 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Rbm4 RNA binding motif protein 4 involved_in ISO (PMID:17284590) RGD PMID:17284590 NCBI chr 1:202,078,442...202,087,506
Ensembl chr 1:202,085,279...202,105,380 		JBrowse link
positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:21518769) RGD PMID:21518769 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
positive regulation of translation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ddx3x DEAD-box helicase 3, X-linked involved_in ISO (PMID:29062139) RGD PMID:29062139 NCBI chr  X:9,479,532...9,493,455
Ensembl chr  X:9,479,532...9,493,168 		JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma 1 involved_in ISO (PMID:29062139) RGD PMID:29062139 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941 		JBrowse link
G Nck1 NCK adaptor protein 1 involved_in ISO
IBA		 (PMID:14676213)
PMID:21873635
UniProtKB:O55033 (MGI:5613478|PMID:14676213)		 RGD PMID:14676213 PMID:21873635 MGI:5613478, RGD:13792537 NCBI chr 8:101,018,610...101,079,237
Ensembl chr 8:101,018,702...101,079,300 		JBrowse link
G Nck2 NCK adaptor protein 2 involved_in ISO
IBA		 UniProtKB:Q99M51 (MGI:5613478|PMID:14676213)
PMID:21873635		 RGD PMID:14676213 PMID:21873635 MGI:5613478, RGD:13792537 NCBI chr 9:45,713,979...45,840,330
Ensembl chr 9:45,714,883...45,840,307 		JBrowse link
positive regulation of translation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkch protein kinase C, eta involved_in ISO (PMID:19797084) RGD PMID:19797084 NCBI chr 6:92,292,000...92,490,663
Ensembl chr 6:92,292,000...92,490,654 		JBrowse link
G Slc35a4 solute carrier family 35, member A4 involved_in ISO (PMID:25621764) RGD PMID:25621764 NCBI chr18:28,280,483...28,284,610
Ensembl chr18:28,279,750...28,284,725 		JBrowse link
positive regulation of translation initiation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5617428|PMID:25329545)		 UniProt
RGD		 PMID:25329545 GO_REF:0000024 MGI:5617428 NCBI chr15:96,025,729...96,065,114
Ensembl chr15:96,025,624...96,065,181 		JBrowse link
positive regulation of translational initiation in response to starvation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
ISO		 GO_REF:0000024
(MGI:2149467|PMID:10655230), (MGI:3589053|PMID:16121183)		 UniProt
RGD		 PMID:10655230 PMID:16121183 GO_REF:0000024 MGI:2149467 MGI:3589053 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Impact impact RWD domain protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5494763|PMID:23447528)		 UniProt
RGD		 PMID:23447528 GO_REF:0000024 MGI:5494763 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
regulation of cytoplasmic translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Impact impact RWD domain protein involved_in ISS
ISO		 GO_REF:0000024
(MGI:5576818|PMID:24333428)		 UniProt
RGD		 PMID:24333428 GO_REF:0000024 MGI:5576818 NCBI chr18:4,108,872...4,147,571
Ensembl chr18:4,108,853...4,147,569 		JBrowse link
regulation of eIF2 alpha phosphorylation by dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:12882984)
GO_REF:0000024		 RGD
UniProt		 PMID:12882984 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
regulation of eIF2 alpha phosphorylation by heme term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1353448|MGI:95513 (MGI:3581470|PMID:15931390)
GO_REF:0000107		 RGD
Ensembl		 PMID:15931390 GO_REF:0000107 MGI:3581470 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Fech ferrochelatase acts_upstream_of_or_within ISO MGI:1353448|MGI:1858114|MGI:95513 (MGI:3581470|PMID:15931390) RGD PMID:15931390 MGI:3581470 NCBI chr18:57,945,123...57,978,327
Ensembl chr18:57,945,122...57,979,348 		JBrowse link
G Hbb hemoglobin subunit beta acts_upstream_of_or_within ISO MGI:1857179 (MGI:3581470|PMID:15931390) RGD PMID:15931390 MGI:3581470 NCBI chr 1:158,250,421...158,251,832
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3582244|PMID:11106749)		 UniProt
RGD		 PMID:11106749 GO_REF:0000024 MGI:3582244 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (MGI:5605960|PMID:11381086) RGD PMID:11381086 MGI:5605960 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
regulation of translation in response to endoplasmic reticulum stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha involved_in ISO (PMID:18508033) RGD PMID:18508033 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
regulation of translational initiation by eIF2 alpha dephosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A involved_in ISO (PMID:12556489) RGD PMID:12556489 NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171 		JBrowse link
regulation of translational initiation by eIF2 alpha phosphorylation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak1 eukaryotic translation initiation factor 2 alpha kinase 1 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr12:10,710,771...10,744,597
Ensembl chr12:10,705,874...10,744,573 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 involved_in ISO (MGI:1858648|PMID:10882126), (MGI:3582244|PMID:11106749), (MGI:3722921|PMID:14729979), (MGI:5613478|PMID:14676213) RGD PMID:10882126 PMID:11106749 PMID:14676213 PMID:14729979 MGI:1858648 MGI:3582244 MGI:3722921 MGI:5613478 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911 		JBrowse link
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000002
UniProtKB:Q9Z2B5 (MGI:2149467|PMID:10655230), (MGI:3582244|PMID:11106749), (MGI:3589053|PMID:16121183), (MGI:3722921|PMID:14729979), (MGI:5700278|PMID:26102367), (MGI:5700304|PMID:16601681), (MGI:5700311|PMID:12176355)
(PMID:26102367)		 UniProt
InterPro
RGD		 PMID:10655230 PMID:11106749 PMID:12176355 PMID:14729979 PMID:16121183 More... GO_REF:0000002 GO_REF:0000024 MGI:2149467 MGI:3582244 MGI:3589053 MGI:3722921 MGI:5700278 MGI:5700304 MGI:5700311 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Pdik1l PDLIM1 interacting kinase 1 like involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 5:146,495,115...146,507,363
Ensembl chr 5:146,495,115...146,506,835 		JBrowse link
G Stk35 serine/threonine kinase 35 involved_in IEA GO_REF:0000108 GOC GO_REF:0000108 NCBI chr 3:117,016,819...117,049,131
Ensembl chr 3:117,016,950...117,048,066 		JBrowse link
regulation of translational initiation in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2ak4 eukaryotic translation initiation factor 2 alpha kinase 4 acts_upstream_of_or_within ISO (MGI:3589702|PMID:15937339) RGD PMID:15937339 MGI:3589702 NCBI chr 3:105,356,261...105,441,630
Ensembl chr 3:105,356,261...105,441,630 		JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha acts_upstream_of_or_within ISO (MGI:3589702|PMID:15937339) RGD PMID:15937339 MGI:3589702 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19818
    cellular process 17392
      cellular response to stimulus 8857
        cellular response to stress 2118
          regulation of translation in response to stress 26
            negative regulation of translation in response to stress + 5
            positive regulation of translation in response to stress + 9
            regulation of cytoplasmic translation in response to stress + 1
            regulation of translation in response to endoplasmic reticulum stress + 13
            regulation of translation in response to osmotic stress + 0
            regulation of translational initiation in response to stress + 18
Path 2
Term Annotations click to browse term
  biological_process 19818
    cellular process 17392
      cellular metabolic process 7496
        cellular biosynthetic process 2928
          cellular nitrogen compound biosynthetic process 2214
            amide biosynthetic process 1368
              peptide biosynthetic process 1238
                translation 1214
                  regulation of translation 529
                    regulation of translation in response to stress 26
                      negative regulation of translation in response to stress + 5
                      positive regulation of translation in response to stress + 9
                      regulation of cytoplasmic translation in response to stress + 1
                      regulation of translation in response to endoplasmic reticulum stress + 13
                      regulation of translation in response to osmotic stress + 0
                      regulation of translational initiation in response to stress + 18
paths to the root