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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of phosphatidylinositol 3-kinase activity
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Accession:GO:0043553 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
Synonyms:exact_synonym: down regulation of phosphatidylinositol 3-kinase activity;   downregulation of phosphatidylinositol 3-kinase activity;   negative regulation of PI3K activity;   negative regulation of phosphoinositide 3-kinase activity
 narrow_synonym: inhibition of phosphatidylinositol 3-kinase activity


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negative regulation of phosphatidylinositol 3-kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dab2ip DAB2 interacting protein IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:19903888)
Ensembl
UniProt
RGD
PMID:19903888 GO_REF:0000024, GO_REF:0000107 NCBI chr 3:14,889,263...15,060,286
Ensembl chr 3:14,889,510...15,060,286
JBrowse link
G Pik3ip1 phosphoinositide-3-kinase interacting protein 1 IEA
ISO
ISS
GO_REF:0000107
(PMID:17475214)
(MGI:MGI:3806716|PMID:18632611)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:17475214, PMID:18632611 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3806716 NCBI chr14:83,559,397...83,572,481
Ensembl chr14:83,560,541...83,572,473
JBrowse link
G Rubcn rubicon autophagy regulator ISO
IBA
(PMID:21062745)
PMID:21873635
RGD PMID:21062745, PMID:21873635 RGD:13792537 NCBI chr11:71,150,506...71,199,254
Ensembl chr11:71,151,132...71,197,035
JBrowse link
G Washc1 WASH complex subunit 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:5519172|PMID:23974797)
Ensembl
RGD
PMID:23974797 GO_REF:0000107, MGI:MGI:5519172 NCBI chr 9:113,918,914...113,936,861
Ensembl chr 9:113,918,858...113,936,860
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20015
    metabolic process 12259
      negative regulation of metabolic process 3316
        negative regulation of lipid metabolic process 107
          negative regulation of lipid kinase activity 5
            negative regulation of phosphatidylinositol 3-kinase activity 4
              negative regulation of 1-phosphatidylinositol-3-kinase activity 0
Path 2
Term Annotations click to browse term
  biological_process 20015
    biological regulation 13760
      regulation of biological process 13073
        regulation of metabolic process 7010
          regulation of cellular metabolic process 6243
            regulation of phosphorus metabolic process 1887
              regulation of phosphate metabolic process 1886
                regulation of phosphorylation 1683
                  regulation of kinase activity 886
                    regulation of lipid kinase activity 64
                      regulation of phosphatidylinositol 3-kinase activity 55
                        negative regulation of phosphatidylinositol 3-kinase activity 4
                          negative regulation of 1-phosphatidylinositol-3-kinase activity 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.