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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of GTPase activity
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Accession:GO:0043547 term browser browse the term
Definition:Any process that activates or increases the activity of a GTPase.
Synonyms:exact_synonym: up regulation of GTPase activity;   upregulation of GTPase activity
 narrow_synonym: activation of GTPase activity;   positive regulation of ARF GTPase activity;   positive regulation of Cdc42 GTPase activity;   positive regulation of Rab GTPase activity;   positive regulation of Rac GTPase activity;   positive regulation of Ral GTPase activity;   positive regulation of Ran GTPase activity;   positive regulation of Rap GTPase activity;   positive regulation of Ras GTPase activity;   positive regulation of Rho GTPase activity;   stimulation of ARF GTPase activity;   stimulation of Cdc42 GTPase activity;   stimulation of GTPase activity;   stimulation of Rab GTPase activity;   stimulation of Rac GTPase activity;   stimulation of Ral GTPase activity;   stimulation of Ran GTPase activity;   stimulation of Rap GTPase activity;   stimulation of Ras GTPase activity;   stimulation of Rho GTPase activity;   up regulation of ARF GTPase activity;   up regulation of Cdc42 GTPase activity;   up regulation of Rab GTPase activity;   up regulation of Rac GTPase activity;   up regulation of Ral GTPase activity;   up regulation of Ran GTPase activity;   up regulation of Rap GTPase activity;   up regulation of Ras GTPase activity;   up regulation of Rho GTPase activity;   upregulation of ARF GTPase activity;   upregulation of Cdc42 GTPase activity;   upregulation of Rab GTPase activity;   upregulation of Rac GTPase activity;   upregulation of Ral GTPase activity;   upregulation of Ran GTPase activity;   upregulation of Rap GTPase activity;   upregulation of Ras GTPase activity;   upregulation of Rho GTPase activity
 alt_id: GO:0032320;   GO:0032321;   GO:0032850;   GO:0032851;   GO:0032852;   GO:0032853;   GO:0032854;   GO:0032855;   GO:0043089


show annotations for term's descendants           Sort by:
positive regulation of GTPase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcyap1 adenylate cyclase activating polypeptide 1 involved_in IDA
ISO		 PMID:23800469
(PMID:23800469)		 RGD PMID:23800469 PMID:23800469 RGD:8554519 NCBI chr 9:113,102,632...113,122,500
Ensembl chr 9:113,103,718...113,109,773 		JBrowse link
G Agrn agrin involved_in IDA PMID:20471381 UniProt PMID:20471381 RGD:8554517 NCBI chr 5:166,749,306...166,782,212
Ensembl chr 5:166,749,310...166,786,003 		JBrowse link
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:16049005)		 UniProt
RGD		 PMID:16049005 GO_REF:0000024 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737 		JBrowse link
G Amph amphiphysin IDA RGD PMID:9348539 RGD:631926 NCBI chr17:45,739,385...45,982,905
Ensembl chr17:45,739,395...45,983,315 		JBrowse link
G Arap1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 involved_in ISO (PMID:11804590) RGD PMID:11804590 NCBI chr 1:155,748,622...155,814,186
Ensembl chr 1:155,748,652...155,814,184 		JBrowse link
G Arhgap11a Rho GTPase activating protein 11A involved_in ISO (PMID:27957544) RGD PMID:27957544 NCBI chr 3:100,590,865...100,607,146
Ensembl chr 3:100,590,865...100,607,559 		JBrowse link
G Arhgap35 Rho GTPase activating protein 35 involved_in IDA PMID:9852136 UniProt PMID:9852136 RGD:11535110 NCBI chr 1:77,202,436...77,319,298
Ensembl chr 1:77,202,436...77,319,298 		JBrowse link
G Arhgap6 Rho GTPase activating protein 6 involved_in ISO (PMID:10699171) RGD PMID:10699171 NCBI chr  X:24,953,464...25,490,003
Ensembl chr  X:24,953,464...25,488,663 		JBrowse link
G Arhgef19 Rho guanine nucleotide exchange factor 19 acts_upstream_of_or_within ISO MGI:2655333 (PMID:20643356) RGD PMID:20643356 NCBI chr 5:153,536,038...153,554,203
Ensembl chr 5:153,536,013...153,554,203 		JBrowse link
G Arhgef5 Rho guanine nucleotide exchange factor 5 acts_upstream_of_or_within ISO (PMID:21525037) RGD PMID:21525037 NCBI chr 4:72,087,205...72,112,316
Ensembl chr 4:72,087,247...72,111,254 		JBrowse link
G Arhgef7 Rho guanine nucleotide exchange factor 7 involved_in
acts_upstream_of_or_within		 ISO (PMID:21048939)
(PMID:21828338)		 RGD PMID:21048939 PMID:21828338 NCBI chr16:77,671,021...77,782,593
Ensembl chr16:77,671,023...77,782,697 		JBrowse link
G Asap3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 involved_in ISO (PMID:18400762) RGD PMID:18400762 NCBI chr 5:148,433,382...148,476,027
Ensembl chr 5:148,433,494...148,474,073 		JBrowse link
G Bcar3 BCAR3 adaptor protein, NSP family member involved_in ISS
ISO		 GO_REF:0000024
(PMID:19086031)		 UniProt
RGD		 PMID:19086031 GO_REF:0000024 NCBI chr 2:210,525,260...210,638,674
Ensembl chr 2:210,525,260...210,638,798 		JBrowse link
G Bin1 bridging integrator 1 IDA RGD PMID:9348539 RGD:631926 NCBI chr18:24,009,731...24,067,267
Ensembl chr18:24,009,653...24,067,263 		JBrowse link
G Cav2 caveolin 2 involved_in ISO (PMID:8552590) RGD PMID:8552590 NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244 		JBrowse link
G Ccl11 C-C motif chemokine ligand 11 involved_in ISO (PMID:19525930) RGD PMID:19525930 NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926 		JBrowse link
G Ccl19 C-C motif chemokine ligand 19 involved_in ISO (PMID:12609829) RGD PMID:12609829 NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308 		JBrowse link
G Ccl24 C-C motif chemokine ligand 24 involved_in ISO (PMID:19525930) RGD PMID:19525930 NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893 		JBrowse link
G Ccl26 C-C motif chemokine ligand 26 involved_in ISO (PMID:19525930) RGD PMID:19525930 NCBI chr12:21,109,384...21,114,336
Ensembl chr12:21,109,421...21,114,335 		JBrowse link
G Dennd1a DENN domain containing 1A involved_in ISO (PMID:20159556) RGD PMID:20159556 NCBI chr 3:21,564,749...22,052,057
Ensembl chr 3:21,564,749...22,052,062 		JBrowse link
G Dennd1b DENN domain containing 1B involved_in ISO (PMID:26774822) RGD PMID:26774822 NCBI chr13:50,545,324...50,772,922
Ensembl chr13:50,545,836...50,770,601 		JBrowse link
G Dock10 dedicator of cytokinesis 10 involved_in ISO (PMID:25851601) RGD PMID:25851601 NCBI chr 9:81,843,599...82,101,540
Ensembl chr 9:81,843,604...82,101,525 		JBrowse link
G Dock11 dedicator of cytokinesis 11 involved_in ISO (PMID:22494997), (PMID:25851601) RGD PMID:22494997 PMID:25851601 NCBI chr  X:115,131,720...115,314,854
Ensembl chr  X:115,131,909...115,314,854 		JBrowse link
G Dock8 dedicator of cytokinesis 8 involved_in ISO (PMID:28028151) RGD PMID:28028151 NCBI chr 1:222,649,309...222,842,474
Ensembl chr 1:222,649,309...222,842,474 		JBrowse link
G Dock9 dedicator of cytokinesis 9 involved_in ISS
ISO		 GO_REF:0000024
(PMID:25851601)		 UniProt
RGD		 PMID:25851601 GO_REF:0000024 NCBI chr15:98,611,518...98,883,306
Ensembl chr15:98,618,084...98,883,153 		JBrowse link
G Dvl2 dishevelled segment polarity protein 2 involved_in ISO (PMID:23109420) RGD PMID:23109420 NCBI chr10:54,723,356...54,732,823
Ensembl chr10:54,723,411...54,732,820 		JBrowse link
G Dvl3 dishevelled segment polarity protein 3 involved_in ISO (PMID:23109420) RGD PMID:23109420 NCBI chr11:80,365,446...80,382,641
Ensembl chr11:80,366,117...80,382,462 		JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:17115030), (PMID:19617897), (PMID:20047078), (PMID:21373644) RGD PMID:17115030 PMID:19617897 PMID:20047078 PMID:21373644 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Evi5 ecotropic viral integration site 5 involved_in ISO (PMID:17562788) RGD PMID:17562788 NCBI chr14:1,875,601...2,021,678
Ensembl chr14:1,875,647...2,021,678 		JBrowse link
G Evi5l ecotropic viral integration site 5-like involved_in ISO (PMID:17646400) RGD PMID:17646400 NCBI chr12:2,519,648...2,558,766
Ensembl chr12:2,519,671...2,559,950 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit involved_in ISO (PMID:20154697) RGD PMID:20154697 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G F2r coagulation factor II (thrombin) receptor involved_in ISO (PMID:23202369) RGD PMID:23202369 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 involved_in ISO (PMID:23202369) RGD PMID:23202369 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Gnao1 G protein subunit alpha o1 IMP RGD PMID:7544301 RGD:2302012 NCBI chr19:11,034,874...11,192,531
Ensembl chr19:11,035,956...11,192,493 		JBrowse link
G Gnb5 G protein subunit beta 5 involved_in ISO (PMID:10521509) RGD PMID:10521509 NCBI chr 8:76,076,120...76,105,069
Ensembl chr 8:76,073,306...76,105,069 		JBrowse link
G Grhl3 grainyhead-like transcription factor 3 acts_upstream_of_or_within ISO MGI:1925912 (PMID:20643356) RGD PMID:20643356 NCBI chr 5:147,774,161...147,806,291
Ensembl chr 5:147,774,160...147,806,160 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta involved_in ISO (PMID:18156211) RGD PMID:18156211 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Hras HRas proto-oncogene, GTPase involved_in ISO (PMID:23027131) RGD PMID:23027131 NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IDA RGD PMID:17662049 RGD:7240703 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Itga6 integrin subunit alpha 6 involved_in ISO (PMID:25911094) RGD PMID:25911094 NCBI chr 3:56,604,512...56,689,428
Ensembl chr 3:56,617,268...56,689,428 		JBrowse link
G Itgb1 integrin subunit beta 1 involved_in ISO (PMID:25911094) RGD PMID:25911094 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195 		JBrowse link
G Kalrn kalirin, RhoGEF kinase acts_upstream_of_or_within ISO MGI:4358076 (PMID:19625617) RGD PMID:19625617 NCBI chr11:66,198,155...66,803,166
Ensembl chr11:66,198,173...66,797,610 		JBrowse link
G Lars1 leucyl-tRNA synthetase 1 involved_in ISO (PMID:22424946) RGD PMID:22424946 NCBI chr18:34,201,555...34,256,003
Ensembl chr18:34,201,549...34,255,931 		JBrowse link
G Lims1 LIM zinc finger domain containing 1 involved_in ISO (PMID:20926685) RGD PMID:20926685 NCBI chr20:26,309,833...26,418,511
Ensembl chr20:26,309,895...26,418,500 		JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IMP basal and EGF-activated Rac1 RGD PMID:17183546 RGD:2292641 NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147 		JBrowse link
G Map4k4 mitogen-activated protein kinase kinase kinase kinase 4 involved_in ISO (PMID:25490267) RGD PMID:25490267 NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698 		JBrowse link
G Mapre2 microtubule-associated protein, RP/EB family, member 2 involved_in ISO (PMID:25490267) RGD PMID:25490267 NCBI chr18:15,028,675...15,169,553
Ensembl chr18:15,029,041...15,168,044 		JBrowse link
G Mex3b mex-3 RNA binding family member B acts_upstream_of_or_within ISO MGI:109338 (PMID:24803656) RGD PMID:24803656 NCBI chr 1:136,855,130...136,859,365
Ensembl chr 1:136,855,130...136,859,354 		JBrowse link
G Mmut methylmalonyl-CoA mutase involved_in ISO (PMID:20876572), (PMID:28497574) RGD PMID:20876572 PMID:28497574 NCBI chr 9:19,928,720...19,956,985
Ensembl chr 9:19,928,727...19,957,046 		JBrowse link
G Myo9b myosin IXb acts_upstream_of_or_within ISO MGI:4867915 (PMID:17314409), (PMID:20566876) RGD PMID:17314409 PMID:20566876 NCBI chr16:17,945,379...18,030,114
Ensembl chr16:17,945,448...18,030,126 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 involved_in ISO (PMID:21283621) RGD PMID:21283621 NCBI chr10:53,505,628...53,582,025
Ensembl chr10:53,516,491...53,570,907 		JBrowse link
G Net1 neuroepithelial cell transforming 1 involved_in ISO (PMID:21373644) RGD PMID:21373644 NCBI chr17:66,341,251...66,370,445
Ensembl chr17:66,340,728...66,370,441 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:1857444|MGI:1857478 (PMID:11435472), (PMID:8563750)
(PMID:16648142)
(PMID:2121371)		 UniProt
RGD		 PMID:2121371 PMID:8563750 PMID:11435472 PMID:16648142 GO_REF:0000024 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ntrk1 neurotrophic receptor tyrosine kinase 1 involved_in
NOT|involved_in		 ISS
ISO		 GO_REF:0000024
(PMID:15488758)		 UniProt
RGD		 PMID:15488758 GO_REF:0000024 NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770 		JBrowse link
G Odam odontogenic, ameloblast associated involved_in ISO (PMID:25911094) RGD PMID:25911094 NCBI chr14:20,193,286...20,202,517
Ensembl chr14:20,193,302...20,202,517 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 involved_in ISO (PMID:20179103) RGD PMID:20179103 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Pkp4 plakophilin 4 involved_in ISO (PMID:17115030) RGD PMID:17115030 NCBI chr 3:43,632,364...43,835,834
Ensembl chr 3:43,631,880...43,835,474 		JBrowse link
G Plxnb1 plexin B1 involved_in ISO (PMID:19788569) RGD PMID:19788569 NCBI chr 8:109,743,470...109,769,153
Ensembl chr 8:109,744,697...109,769,027 		JBrowse link
G Prex1 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 acts_upstream_of_or_within ISO MGI:98923 (PMID:21178006) RGD PMID:21178006 NCBI chr 3:155,306,950...155,456,688
Ensembl chr 3:155,306,950...155,456,688 		JBrowse link
G Prtn3 proteinase 3 involved_in ISO (PMID:23202369) RGD PMID:23202369 NCBI chr 7:9,822,123...9,831,300
Ensembl chr 7:9,822,122...9,831,944 		JBrowse link
G Rab11fip2 RAB11 family interacting protein 2 involved_in ISO (PMID:30883606) RGD PMID:30883606 NCBI chr 1:258,950,535...259,094,555
Ensembl chr 1:258,923,873...259,093,752 		JBrowse link
G Rab3gap1 RAB3 GTPase activating protein catalytic subunit 1 involved_in ISO (PMID:24891604)
(PMID:16782817)		 RGD PMID:16782817 PMID:24891604 NCBI chr13:39,355,698...39,429,154
Ensembl chr13:39,352,247...39,429,169 		JBrowse link
G Rack1 receptor for activated C kinase 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20499158)		 UniProt
RGD		 PMID:20499158 GO_REF:0000024 NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975 		JBrowse link
G Ralbp1 ralA binding protein 1 involved_in ISO (PMID:7673236)
(PMID:8570186)		 RGD PMID:7673236 PMID:8570186 NCBI chr 9:105,456,425...105,493,235
Ensembl chr 9:105,456,425...105,492,707 		JBrowse link
G Rap1a RAP1A, member of RAS oncogene family involved_in IMP PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 2:193,208,631...193,286,513
Ensembl chr 2:193,208,635...193,286,501 		JBrowse link
G Rap1gap Rap1 GTPase-activating protein involved_in ISO (PMID:15141215) RGD PMID:15141215 NCBI chr 5:149,873,987...149,939,254
Ensembl chr 5:149,892,019...149,939,253 		JBrowse link
G Rap1gds1 Rap1 GTPase-GDP dissociation stimulator 1 IMP RGD PMID:18348285 RGD:2314690 NCBI chr 2:227,500,366...227,645,213
Ensembl chr 2:227,500,367...227,645,169 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 involved_in ISO (PMID:10548487), (PMID:21840392) RGD PMID:10548487 PMID:21840392 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rapgef2 Rap guanine nucleotide exchange factor 2 involved_in ISS
ISO
IDA
IMP		 GO_REF:0000024
(PMID:16272156), (PMID:19635461), (PMID:23800469)
(PMID:10548487), (PMID:10608844), (PMID:10801446), (PMID:11359771), (PMID:16272156), (PMID:17724123), (PMID:21840392), (PMID:22797597), (PMID:23800469)
PMID:21382555		 UniProt
RGD		 PMID:10548487 PMID:10608844 PMID:10801446 PMID:11359771 PMID:16272156 More... GO_REF:0000024, RGD:7241548, RGD:8554481 NCBI chr 2:164,207,513...164,322,157
Ensembl chr 2:164,207,513...164,244,247 		JBrowse link
G Rapgef3 Rap guanine nucleotide exchange factor 3 involved_in ISS
ISO		 GO_REF:0000024
(PMID:21840392)		 UniProt
RGD		 PMID:21840392 GO_REF:0000024 NCBI chr 7:128,875,772...128,898,203
Ensembl chr 7:128,875,773...128,898,521 		JBrowse link
G Rapgef6 Rap guanine nucleotide exchange factor 6 involved_in ISO (PMID:22797597) RGD PMID:22797597 NCBI chr10:38,655,854...38,824,227
Ensembl chr10:38,655,867...38,823,211 		JBrowse link
G Rasa1 RAS p21 protein activator 1 IMP RGD PMID:14707121 RGD:9999423 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 involved_in IMP
ISO
ISS		 (PMID:17135267) RGD PMID:17135267 PMID:15798216 PMID:17135267 RGD:10003119, RGD:8554560 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rasgrp2 RAS guanyl releasing protein 2 involved_in ISO (PMID:24958846) RGD PMID:24958846 NCBI chr 1:203,705,777...203,722,993
Ensembl chr 1:203,707,481...203,722,993 		JBrowse link
G Rgma repulsive guidance molecule BMP co-receptor a acts_upstream_of_or_within ISO (PMID:26651291) RGD PMID:26651291 NCBI chr 1:127,128,934...127,172,918
Ensembl chr 1:127,128,934...127,172,918 		JBrowse link
G Rgn regucalcin IDA RGD PMID:11693188 RGD:9590216 NCBI chr  X:1,619,030...1,634,456
Ensembl chr  X:1,619,032...1,634,450 		JBrowse link
G Rgp1 RGP1 homolog, RAB6A GEF complex partner 1 involved_in ISO (PMID:23091056) RGD PMID:23091056 NCBI chr 5:57,834,467...57,843,087
Ensembl chr 5:57,834,629...57,843,086 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10480894), (PMID:18434541)		 UniProt
RGD		 PMID:10480894 PMID:18434541 GO_REF:0000024 NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 involved_in ISS
ISO		 GO_REF:0000024
(PMID:18434541)		 UniProt
RGD		 PMID:18434541 GO_REF:0000024 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 involved_in ISO (PMID:10926822) RGD PMID:10926822 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rgs16 regulator of G-protein signaling 16 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10373502)
(PMID:18434541)		 UniProt
RGD		 PMID:10373502 PMID:18434541 GO_REF:0000024 NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IMP RGD PMID:20530129 PMID:9430692 RGD:7207369, RGD:7207375 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs6 regulator of G-protein signaling 6 involved_in ISS
ISO		 GO_REF:0000024
(PMID:10521509)		 UniProt
RGD		 PMID:10521509 GO_REF:0000024 NCBI chr 6:102,264,451...102,796,311
Ensembl chr 6:102,264,447...102,824,753 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 involved_in ISO (PMID:10521509) RGD PMID:10521509 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 involved_in IDA
ISO		 PMID:9394004
(PMID:18434541)		 RGD PMID:18434541 PMID:9394004 RGD:69963 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Ric1 RIC1 homolog, RAB6A GEF complex partner 1 involved_in ISO (PMID:23091056) RGD PMID:23091056 NCBI chr 1:227,285,510...227,384,553
Ensembl chr 1:227,285,210...227,382,863 		JBrowse link
G Rsu1 Ras suppressor protein 1 involved_in ISO (PMID:20926685) RGD PMID:20926685 NCBI chr17:76,128,774...76,377,515
Ensembl chr17:76,188,812...76,377,454 		JBrowse link
G Rtn4r reticulon 4 receptor involved_in ISS
ISO		 GO_REF:0000024
(PMID:22923615)		 UniProt
RGD		 PMID:22923615 GO_REF:0000024 NCBI chr11:82,844,309...82,869,251
Ensembl chr11:82,844,309...82,869,466 		JBrowse link
G S100a10 S100 calcium binding protein A10 involved_in ISO (PMID:23129259) RGD PMID:23129259 NCBI chr 2:179,221,012...179,229,659
Ensembl chr 2:179,220,887...179,229,661 		JBrowse link
G S1pr1 sphingosine-1-phosphate receptor 1 IDA RGD PMID:14711826 RGD:1304283 NCBI chr 2:203,624,752...203,629,110
Ensembl chr 2:203,621,587...203,629,681 		JBrowse link
G Sema4d semaphorin 4D involved_in ISO (PMID:19788569) RGD PMID:19788569 NCBI chr17:13,430,324...13,537,146
Ensembl chr17:13,430,379...13,537,138 		JBrowse link
G Sgsm2 small G protein signaling modulator 2 involved_in ISO (PMID:21808068) RGD PMID:21808068 NCBI chr10:59,718,180...59,759,822
Ensembl chr10:59,718,183...59,759,447 		JBrowse link
G Sgsm3 small G protein signaling modulator 3 involved_in ISO (PMID:17562788) RGD PMID:17562788 NCBI chr 7:112,514,453...112,544,109
Ensembl chr 7:112,514,630...112,544,108 		JBrowse link
G Sh3bp1 SH3-domain binding protein 1 involved_in IMP
ISO
ISS		 PMID:21658605
(PMID:7621827)
(PMID:22891260), (PMID:24841563)
GO_REF:0000024		 RGD
UniProt		 PMID:7621827 PMID:22891260 PMID:24841563 PMID:21658605 GO_REF:0000024, RGD:13210533 NCBI chr 7:110,457,626...110,470,201
Ensembl chr 7:110,457,710...110,470,201 		JBrowse link
G Snx13 sorting nexin 13 involved_in ISO (PMID:11729322) RGD PMID:11729322 NCBI chr 6:51,758,258...51,862,260
Ensembl chr 6:51,753,036...51,860,224 		JBrowse link
G Snx18 sorting nexin 18 involved_in ISO (PMID:20427313) RGD PMID:20427313 NCBI chr 2:45,232,325...45,258,345
Ensembl chr 2:45,232,325...45,258,345 		JBrowse link
G Snx9 sorting nexin 9 involved_in ISO (PMID:15703209) RGD PMID:15703209 NCBI chr 1:46,424,897...46,510,096
Ensembl chr 1:46,423,553...46,509,036 		JBrowse link
G Srgap2 SLIT-ROBO Rho GTPase activating protein 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19737524)
(PMID:20810653), (PMID:21148482), (PMID:27373832)		 UniProt
RGD		 PMID:19737524 PMID:20810653 PMID:21148482 PMID:27373832 GO_REF:0000024 NCBI chr13:42,745,956...42,967,091
Ensembl chr13:42,745,947...42,967,058 		JBrowse link
G Tbc1d2 TBC1 domain family, member 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20116244)		 UniProt
RGD		 PMID:20116244 GO_REF:0000024 NCBI chr 5:60,884,114...60,931,717
Ensembl chr 5:60,884,124...60,931,352 		JBrowse link
G Tbc1d20 TBC1 domain family, member 20 involved_in ISO (PMID:17684057) RGD PMID:17684057 NCBI chr 3:140,768,537...140,787,010
Ensembl chr 3:140,768,537...140,785,121 		JBrowse link
G Tbc1d30 TBC1 domain family, member 30 involved_in ISO (PMID:17646400) RGD PMID:17646400 NCBI chr 7:56,779,570...56,869,092
Ensembl chr 7:56,782,165...56,870,515 		JBrowse link
G Tbc1d7 TBC1 domain family, member 7 involved_in ISO (PMID:17646400) RGD PMID:17646400 NCBI chr17:21,530,709...21,548,556
Ensembl chr17:21,531,016...21,548,553 		JBrowse link
G Tgm2 transglutaminase 2 involved_in ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981 		JBrowse link
G Thy1 Thy-1 cell surface antigen involved_in IDA PMID:15093746 UniProt PMID:15093746 RGD:8553684 NCBI chr 8:44,389,495...44,394,688
Ensembl chr 8:44,389,513...44,394,659 		JBrowse link
G Usp17la2 ubiquitin specific peptidase 17-like a2 involved_in ISO (PMID:21448158) RGD PMID:21448158 NCBI chr 1:159,151,417...159,155,192
Ensembl chr 1:159,151,432...159,155,192 		JBrowse link
G Usp6nl USP6 N-terminal like involved_in ISO (PMID:17562788) RGD PMID:17562788 NCBI chr17:71,828,433...71,956,878
Ensembl chr17:71,830,469...71,956,027 		JBrowse link
G Vav1 vav guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:3040696 (PMID:21178006) RGD PMID:21178006 NCBI chr 9:2,161,985...2,209,951
Ensembl chr 9:2,157,900...2,208,937 		JBrowse link
G Wnt4 Wnt family member 4 involved_in ISO UniProtKB:P01112 (PMID:23027131) RGD PMID:23027131 NCBI chr 5:149,513,573...149,535,415
Ensembl chr 5:149,514,018...149,532,859 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:23109420) RGD PMID:23109420 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
G Zc3h15 zinc finger CCCH-type containing 15 involved_in ISO (PMID:23711155) RGD PMID:23711155 NCBI chr 3:68,744,591...68,764,335
Ensembl chr 3:68,744,604...68,764,333 		JBrowse link
activation of GTPase activity term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase involved_in ISO (PMID:7479768) RGD PMID:7479768 NCBI chr10:61,262,516...61,461,331
Ensembl chr10:61,262,516...61,461,505 		JBrowse link
G Akt2 AKT serine/threonine kinase 2 acts_upstream_of_or_within ISO MGI:2444531|MGI:3036245 (PMID:21148297) RGD PMID:21148297 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817 		JBrowse link
G Apc2 APC regulator of WNT signaling pathway 2 involved_in ISO (PMID:25753423) RGD PMID:25753423 NCBI chr 7:9,392,336...9,414,364
Ensembl chr 7:9,392,336...9,414,310 		JBrowse link
G Arhgap24 Rho GTPase activating protein 24 acts_upstream_of_or_within ISO (PMID:21911940) RGD PMID:21911940 NCBI chr14:6,800,624...7,183,877
Ensembl chr14:6,800,631...7,183,823 		JBrowse link
G Arhgap42 Rho GTPase activating protein 42 involved_in ISO (PMID:24335996) RGD PMID:24335996 NCBI chr 8:6,154,759...6,384,497
Ensembl chr 8:6,156,865...6,384,870 		JBrowse link
G Arhgef10 Rho guanine nucleotide exchange factor 10 involved_in ISO (PMID:16896804) RGD PMID:16896804 NCBI chr16:74,647,147...74,738,784
Ensembl chr16:74,647,153...74,738,173 		JBrowse link
G Arhgef16 Rho guanine nucleotide exchange factor 16 involved_in ISO (PMID:20679435), (PMID:21139582) RGD PMID:20679435 PMID:21139582 NCBI chr 5:164,843,656...164,866,212
Ensembl chr 5:164,844,161...164,866,212 		JBrowse link
G Bcr BCR activator of RhoGEF and GTPase involved_in ISO (PMID:23940119), (PMID:7479768) RGD PMID:7479768 PMID:23940119 NCBI chr20:13,469,325...13,596,942
Ensembl chr20:13,471,668...13,597,016 		JBrowse link
G Ccdc125 coiled-coil domain containing 125 involved_in ISO (PMID:19787194) RGD PMID:19787194 NCBI chr 2:31,809,120...31,835,538
Ensembl chr 2:31,809,228...31,850,152 		JBrowse link
G Coro1c coronin 1C involved_in ISO UniProtKB:Q8BK67 (PMID:25074804) RGD PMID:25074804 NCBI chr12:42,713,024...42,785,179
Ensembl chr12:42,712,991...42,785,179 		JBrowse link
G Crk CRK proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:104580|MGI:104686|MGI:97302 (PMID:25621495) RGD PMID:25621495 NCBI chr10:60,530,469...60,556,703
Ensembl chr10:60,530,464...60,553,406 		JBrowse link
G Crkl CRK like proto-oncogene, adaptor protein acts_upstream_of_or_within ISO MGI:104580|MGI:88508|MGI:97302 (PMID:25621495) RGD PMID:25621495 NCBI chr11:83,528,788...83,563,214
Ensembl chr11:83,526,530...83,563,238 		JBrowse link
G Cxcl13 C-X-C motif chemokine ligand 13 involved_in ISO (PMID:15972452) RGD PMID:15972452 NCBI chr14:13,608,894...13,613,965
Ensembl chr14:13,608,902...13,613,933 		JBrowse link
G Dock7 dedicator of cytokinesis 7 involved_in ISO (PMID:16982419) RGD PMID:16982419 NCBI chr 5:113,599,371...113,782,871
Ensembl chr 5:113,600,198...113,782,813 		JBrowse link
G Ect2 epithelial cell transforming 2 involved_in ISO (PMID:19617897) RGD PMID:19617897 NCBI chr 2:109,975,813...110,037,911
Ensembl chr 2:109,975,813...110,037,911 		JBrowse link
G Eif5 eukaryotic translation initiation factor 5 IDA RGD PMID:10805737 RGD:10755758 NCBI chr 6:130,589,162...130,597,656
Ensembl chr 6:130,589,143...130,597,656 		JBrowse link
G Epha1 Eph receptor A1 involved_in ISO (PMID:19118217) RGD PMID:19118217 NCBI chr 4:71,246,409...71,260,920
Ensembl chr 4:71,246,409...71,260,846 		JBrowse link
G Epha2 Eph receptor A2 involved_in ISO (PMID:20679435) RGD PMID:20679435 NCBI chr 5:153,605,644...153,634,115
Ensembl chr 5:153,605,644...153,634,117 		JBrowse link
G Foxj1 forkhead box J1 involved_in ISO (PMID:17488776) RGD PMID:17488776 NCBI chr10:101,566,299...101,570,370
Ensembl chr10:101,566,304...101,570,237 		JBrowse link
G Gpr65 G-protein coupled receptor 65 involved_in ISO (PMID:15618224) RGD PMID:15618224 NCBI chr 6:117,515,786...117,536,514
Ensembl chr 6:117,515,648...117,536,512 		JBrowse link
G Iqsec3 IQ motif and Sec7 domain ArfGEF 3 involved_in IDA PMID:21198641 UniProt PMID:21198641 RGD:8554231 NCBI chr 4:154,610,933...154,707,310
Ensembl chr 4:154,610,934...154,707,310 		JBrowse link
G Mtss2 MTSS I-BAR domain containing 2 involved_in ISO (PMID:20875796) RGD PMID:20875796 NCBI chr19:38,692,793...38,714,575
Ensembl chr19:38,693,194...38,713,507 		JBrowse link
G Ndel1 nudE neurodevelopment protein 1-like 1 acts_upstream_of_or_within ISO (PMID:18331715) RGD PMID:18331715 NCBI chr10:53,505,628...53,582,025
Ensembl chr10:53,516,491...53,570,907 		JBrowse link
G Nedd9 neural precursor cell expressed, developmentally down-regulated 9 acts_upstream_of_or_within ISO MGI:104580|MGI:104686|MGI:88508 (PMID:25621495) RGD PMID:25621495 NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019 		JBrowse link
G Ntf3 neurotrophin 3 involved_in ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596 		JBrowse link
G Ntrk3 neurotrophic receptor tyrosine kinase 3 involved_in ISO (PMID:23027130) RGD PMID:23027130 NCBI chr 1:132,116,472...132,503,849
Ensembl chr 1:132,132,849...132,503,286 		JBrowse link
G Pip5k1a phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha involved_in ISO (PMID:20660631) RGD PMID:20660631 NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15158121 RGD:1642626 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ralgapa1 Ral GTPase activating protein catalytic subunit alpha 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:19520869)		 UniProt
RGD		 PMID:19520869 GO_REF:0000024 NCBI chr 6:72,977,432...73,252,378
Ensembl chr 6:72,977,432...73,252,378 		JBrowse link
G Ralgapa2 Ral GTPase activating protein catalytic subunit alpha 2 involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:19520869
MGI:2444531 (PMID:21148297)		 RGD PMID:21148297 PMID:19520869 RGD:8553279 NCBI chr 3:133,658,725...133,938,821
Ensembl chr 3:133,659,761...133,938,916 		JBrowse link
G Ralgapb Ral GTPase activating protein non-catalytic subunit beta involved_in
acts_upstream_of_or_within		 IDA
ISO		 PMID:19520869
MGI:3036245 (PMID:21148297)		 RGD PMID:21148297 PMID:19520869 RGD:8553279 NCBI chr 3:147,062,443...147,152,090
Ensembl chr 3:147,062,364...147,152,090 		JBrowse link
G Rangap1 RAN GTPase activating protein 1 involved_in ISO (PMID:16428860) RGD PMID:16428860 NCBI chr 7:113,224,695...113,250,441
Ensembl chr 7:113,224,703...113,250,438 		JBrowse link
G Rapgef1 Rap guanine nucleotide exchange factor 1 acts_upstream_of_or_within ISO MGI:104686|MGI:88508|MGI:97302 (PMID:25621495) RGD PMID:25621495 NCBI chr 3:12,898,349...13,016,234
Ensembl chr 3:12,898,266...13,013,984 		JBrowse link
G Rasa1 RAS p21 protein activator 1 IDA RGD PMID:8226805 RGD:9999452 NCBI chr 2:15,857,704...15,940,757
Ensembl chr 2:15,857,980...15,940,854 		JBrowse link
G Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 involved_in IMP
ISS
ISO		 PMID:17135267
(PMID:17135267)		 RGD PMID:17135267 PMID:1379346 PMID:17135267 RGD:10003125, RGD:8554560 NCBI chr 8:90,445,154...90,574,274
Ensembl chr 8:90,445,154...90,574,269 		JBrowse link
G Rasgrp1 RAS guanyl releasing protein 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:10807788), (PMID:12845332)
MGI:2386261 (PMID:17190838)
(PMID:11017103)		 RGD PMID:10807788 PMID:11017103 PMID:12845332 PMID:17190838 NCBI chr 3:104,168,549...104,230,107
Ensembl chr 3:104,170,013...104,230,056 		JBrowse link
G Rcc2 regulator of chromosome condensation 2 involved_in ISO UniProtKB:Q9WUM4 (PMID:25074804) RGD PMID:25074804 NCBI chr 5:152,994,406...153,017,223
Ensembl chr 5:152,993,665...153,017,205 		JBrowse link
G Rhog ras homolog family member G involved_in ISO (PMID:20679435) RGD PMID:20679435 NCBI chr 1:156,618,713...156,630,710
Ensembl chr 1:156,615,349...156,631,257 		JBrowse link
G Scrib scribble planar cell polarity protein involved_in ISO (PMID:19041750) RGD PMID:19041750 NCBI chr 7:107,759,343...107,782,364
Ensembl chr 7:107,759,343...107,782,331 		JBrowse link
G Sipa1l1 signal-induced proliferation-associated 1 like 1 involved_in IDA PMID:11502259 UniProt PMID:11502259 RGD:8554032 NCBI chr 6:101,839,351...102,118,408
Ensembl chr 6:101,839,404...102,116,950 		JBrowse link
G Slc27a4 solute carrier family 27 member 4 acts_upstream_of_or_within ISO (PMID:25603556) RGD PMID:25603556 NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943 		JBrowse link
G Tax1bp3 Tax1 binding protein 3 involved_in ISO (PMID:21139582) RGD PMID:21139582 NCBI chr10:57,795,845...57,800,363
Ensembl chr10:57,795,382...57,800,363 		JBrowse link
G Tbc1d7 TBC1 domain family, member 7 involved_in ISO (PMID:22795129) RGD PMID:22795129 NCBI chr17:21,530,709...21,548,556
Ensembl chr17:21,531,016...21,548,553 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 involved_in IMP
ISO		 (PMID:23109420) RGD PMID:23109420 PMID:18930714 RGD:10043296 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
G Tsc1 TSC complex subunit 1 involved_in ISO (PMID:10806479) RGD PMID:10806479 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674 		JBrowse link
G Wnt5a Wnt family member 5A involved_in ISO (PMID:18953410) RGD PMID:18953410 NCBI chr16:3,697,032...3,718,230
Ensembl chr16:3,697,032...3,718,234 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20075
    biological regulation 13559
      regulation of molecular function 1784
        regulation of catalytic activity 1187
          regulation of hydrolase activity 520
            regulation of GTPase activity 186
              positive regulation of GTPase activity 149
                activation of GTPase activity 46
paths to the root