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Term:molybdopterin cofactor binding
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Accession:GO:0043546 term browser browse the term
Definition:Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: Moco binding

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molybdopterin cofactor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aox1 aldehyde oxidase 1 enables ISO (PMID:26322824), (PMID:26842593) UniProt PMID:26322824 PMID:26842593 NCBI chrNW_004936825:263,725...332,424 JBrowse link
G Gphn gephyrin enables ISO (PMID:9990024) CAFA PMID:9990024 NCBI chrNW_004936495:9,970,683...10,565,467 JBrowse link
G Mtarc1 mitochondrial amidoxime reducing component 1 enables ISO (PMID:20861021), (PMID:30397129) UniProt PMID:20861021 PMID:30397129 NCBI chrNW_004936650:1,477,138...1,504,501 JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 enables ISO (PMID:20861021) UniProt PMID:20861021 NCBI chrNW_004936650:1,506,471...1,543,532 JBrowse link
G Suox sulfite oxidase ISO RGD PMID:8276806 RGD:634113 NCBI chrNW_004936646:411,543...415,709 JBrowse link
G Xdh xanthine dehydrogenase enables ISO (PMID:17301077)
UniProt PMID:15878860 PMID:17301077 RGD:8553512 NCBI chrNW_004936493:1,762,814...1,824,501 JBrowse link

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  molecular_function 14246
    binding 13489
      heterocyclic compound binding 2456
        molybdopterin cofactor binding 6
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