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ONTOLOGY REPORT - ANNOTATIONS


Term:molybdopterin cofactor binding
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Accession:GO:0043546 term browser browse the term
Definition:Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: Moco binding


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molybdopterin cofactor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOX1 aldehyde oxidase 1 enables IDA (PMID:26322824), (PMID:26842593) UniProt PMID:26322824 PMID:26842593 NCBI chr 2:200,585,952...200,677,064
Ensembl chr 2:200,586,014...200,677,064
JBrowse link
G GPHN gephyrin enables IDA (PMID:9990024) CAFA PMID:9990024 NCBI chr14:66,507,934...67,181,805
Ensembl chr14:66,507,407...67,181,803
JBrowse link
G MTARC1 mitochondrial amidoxime reducing component 1 enables IBA
IDA
(PMID:21873635)
(PMID:20861021), (PMID:30397129)
GO_Central
UniProt
PMID:20861021 PMID:21873635 PMID:30397129 NCBI chr 1:220,786,697...220,819,659
Ensembl chr 1:220,786,913...220,819,659
JBrowse link
G MTARC2 mitochondrial amidoxime reducing component 2 enables IDA
IBA
(PMID:20861021)
(PMID:21873635)
UniProt
GO_Central
PMID:20861021 PMID:21873635 NCBI chr 1:220,747,417...220,784,815
Ensembl chr 1:220,748,225...220,784,815
JBrowse link
G SUOX sulfite oxidase enables IBA
ISO
(PMID:21873635) GO_Central
RGD
PMID:8276806 PMID:21873635 RGD:634113 NCBI chr12:55,992,547...56,005,525
Ensembl chr12:55,997,180...56,006,641
JBrowse link
G XDH xanthine dehydrogenase enables IDA (PMID:17301077) UniProt PMID:17301077 NCBI chr 2:31,334,320...31,414,777
Ensembl chr 2:31,334,321...31,414,742
JBrowse link

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  molecular_function 18838
    binding 17198
      heterocyclic compound binding 6189
        molybdopterin cofactor binding 6
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