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Term:molybdopterin cofactor binding
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Accession:GO:0043546 term browser browse the term
Definition:Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: Moco binding

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molybdopterin cofactor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AOX1 aldehyde oxidase 1 enables ISO (PMID:26322824), (PMID:26842593) UniProt PMID:26322824 PMID:26842593 NCBI chr2B:87,839,376...87,924,823
Ensembl chr2B:205,996,604...206,083,897
JBrowse link
G GPHN gephyrin enables ISO (PMID:9990024) CAFA PMID:9990024 NCBI chr14:47,081,527...47,755,182
Ensembl chr14:66,137,166...66,634,550
JBrowse link
G MTARC1 mitochondrial amidoxime reducing component 1 enables ISO (PMID:20861021), (PMID:30397129) UniProt PMID:20861021 PMID:30397129 NCBI chr 1:196,373,028...196,405,115 JBrowse link
G MTARC2 mitochondrial amidoxime reducing component 2 enables ISO (PMID:20861021) UniProt PMID:20861021 NCBI chr 1:196,333,803...196,371,147
Ensembl chr 1:201,369,424...201,405,602
JBrowse link
G SUOX sulfite oxidase ISO RGD PMID:8276806 RGD:634113 NCBI chr12:32,907,456...32,915,788
Ensembl chr12:33,157,277...33,165,661
JBrowse link
G XDH xanthine dehydrogenase enables ISO PMID:15878860
UniProt PMID:15878860 PMID:17301077 RGD:8553512 NCBI chr2A:31,356,011...31,435,111
Ensembl chr2A:31,425,183...31,504,455
JBrowse link

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  molecular_function 15012
    binding 14201
      heterocyclic compound binding 2538
        molybdopterin cofactor binding 6
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