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ONTOLOGY REPORT - ANNOTATIONS


Term:molybdopterin cofactor binding
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Accession:GO:0043546 term browser browse the term
Definition:Binding to a molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: Moco binding


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molybdopterin cofactor binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aox1 aldehyde oxidase 1 enables IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:26322824), (PMID:26842593)
Ensembl
UniProt
RGD
PMID:26322824 PMID:26842593 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:59,579,621...59,658,772
Ensembl chr 9:59,579,649...59,658,770
JBrowse link
G Aox2 aldehyde oxidase 2 enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,828,403...59,916,175
Ensembl chr 9:59,828,084...59,916,146
JBrowse link
G Aox3 aldehyde oxidase 3 enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,664,784...59,749,814 JBrowse link
G Aox4 aldehyde oxidase 4 enables ISS GO_REF:0000024 UniProt GO_REF:0000024 NCBI chr 9:59,761,238...59,818,169
Ensembl chr 9:59,664,809...59,818,169
JBrowse link
G Gphn gephyrin enables ISO
IEA
(PMID:9990024)
GO_REF:0000107
RGD
Ensembl
PMID:9990024 GO_REF:0000107 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G LOC100910481 MOSC domain-containing protein 2, mitochondrial-like enables IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537
G Mtarc1 mitochondrial amidoxime reducing component 1 enables IBA
ISO
PMID:21873635
(PMID:20861021), (PMID:30397129)
RGD PMID:20861021 PMID:30397129 PMID:21873635 RGD:13792537 NCBI chr13:96,324,377...96,362,677 JBrowse link
G Mtarc2 mitochondrial amidoxime reducing component 2 enables IBA
ISO
PMID:21873635
(PMID:20861021)
RGD PMID:20861021 PMID:21873635 RGD:13792537 NCBI chr13:96,362,810...96,397,284 JBrowse link
G Suox sulfite oxidase enables IDA
IEA
IBA
GO_REF:0000002
PMID:21873635
InterPro PMID:8276806 PMID:21873635 GO_REF:0000002, RGD:634113, RGD:13792537 NCBI chr 7:1,103,149...1,107,156
Ensembl chr 7:1,103,151...1,107,038
JBrowse link
G Xdh xanthine dehydrogenase enables ISS
ISO
IEA
IDA
GO_REF:0000024
(PMID:17301077)
GO_REF:0000107
PMID:15878860
UniProt
RGD
Ensembl
PMID:17301077 PMID:15878860 GO_REF:0000024 GO_REF:0000107, RGD:8553512 NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268
JBrowse link

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  molecular_function 19979
    binding 17009
      heterocyclic compound binding 5667
        molybdopterin cofactor binding 10
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