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ONTOLOGY REPORT - ANNOTATIONS


Term:molybdopterin cofactor metabolic process
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Accession:GO:0043545 term browser browse the term
Definition:The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: Moco metabolic process;   Moco metabolism;   molybdopterin cofactor metabolism


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molybdopterin cofactor metabolic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocos molybdenum cofactor sulfurase ISO
IBA
(PMID:11302742)
PMID:21873635
RGD PMID:11302742, PMID:21873635 RGD:13792537 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
Mo-molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin ISO
IBA
IEA
IDA
MGI:MGI:2182559 (MGI:MGI:2182545|PMID:9812897)
PMID:21873635
GO_REF:0000104
PMID:23163752
RGD
UniProt
PMID:9812897, PMID:21873635, PMID:23163752 GO_REF:0000104, MGI:MGI:2182545, RGD:13792537, RGD:8554131 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Mocos molybdenum cofactor sulfurase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr18:16,590,086...16,636,312
Ensembl chr18:16,590,197...16,636,084
JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 ISO (PMID:15180982), (PMID:16021469), (PMID:9731530), (PMID:9921896) RGD PMID:9731530, PMID:9921896, PMID:15180982, PMID:16021469 NCBI chr 9:13,493,705...13,513,972
Ensembl chr 9:13,493,709...13,513,960
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 ISS
ISO
GO_REF:0000024
(PMID:10053004), (PMID:12732628), (PMID:15073332)
UniProt
RGD
PMID:10053004, PMID:12732628, PMID:15073332 GO_REF:0000024 NCBI chr 2:46,980,964...46,992,886
Ensembl chr 2:46,980,976...46,992,883
JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 ISO (PMID:15073332) RGD PMID:15073332 NCBI chr 3:164,986,421...164,988,381
Ensembl chr 3:164,986,421...164,988,369
JBrowse link
G Nfs1 NFS1 cysteine desulfurase IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:151,665,813...151,688,151
Ensembl chr 3:151,665,814...151,688,149
Ensembl chr 3:151,665,814...151,688,149
JBrowse link
molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin ISO
IEA
IBA
(PMID:26613940), (PMID:9990024)
GO_REF:0000104
PMID:21873635
RGD
UniProt
PMID:9990024, PMID:26613940, PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:101,327,874...101,859,169
Ensembl chr 6:101,532,518...101,859,164
JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 ISO MGI:MGI:2659140 (MGI:MGI:2447229|PMID:12471057), (MGI:MGI:3576970|PMID:15862276), (MGI:MGI:3757917|PMID:17236133) RGD PMID:12471057, PMID:15862276, PMID:17236133 MGI:MGI:2447229, MGI:MGI:3576970, MGI:MGI:3757917 NCBI chr 9:13,493,705...13,513,972
Ensembl chr 9:13,493,709...13,513,960
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      prosthetic group metabolic process 6
        molybdopterin cofactor metabolic process 6
          Mo-molybdopterin cofactor metabolic process + 6
          W-molybdopterin cofactor metabolic process + 0
          molybdopterin cofactor biosynthetic process 2
          molybdopterin cofactor catabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    metabolic process 12256
      organic substance metabolic process 11636
        macromolecule metabolic process 10081
          protein metabolic process 6214
            cellular protein metabolic process 5552
              prosthetic group metabolic process 6
                molybdopterin cofactor metabolic process 6
                  Mo-molybdopterin cofactor metabolic process + 6
                  W-molybdopterin cofactor metabolic process + 0
                  molybdopterin cofactor biosynthetic process 2
                  molybdopterin cofactor catabolic process + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.