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ONTOLOGY REPORT - ANNOTATIONS


Term:molybdopterin cofactor metabolic process
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Accession:GO:0043545 term browser browse the term
Definition:The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
Synonyms:exact_synonym: Moco metabolic process;   Moco metabolism;   molybdopterin cofactor metabolism



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molybdopterin cofactor metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mocos molybdenum cofactor sulfurase involved_in IBA
ISO
PMID:21873635
(PMID:11302742)
RGD PMID:11302742 PMID:21873635 RGD:13792537 NCBI chr18:15,931,654...15,977,415
Ensembl chr18:15,931,654...15,977,187
JBrowse link
Mo-molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in
acts_upstream_of_or_within
IEA
IBA
IDA
ISO
GO_REF:0000104
PMID:21873635
PMID:23163752
MGI:2182559 (MGI:2182545|PMID:9812897)
UniProt
RGD
PMID:9812897 PMID:21873635 PMID:23163752 PMID:21873635 GO_REF:0000104 MGI:2182545, RGD:13792537, RGD:8554131, RGD:13792537 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Mocos molybdenum cofactor sulfurase involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr18:15,931,654...15,977,415
Ensembl chr18:15,931,654...15,977,187
JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 involved_in ISO (PMID:15180982)
(PMID:16021469), (PMID:9731530), (PMID:9921896)
RGD PMID:9731530 PMID:9921896 PMID:15180982 PMID:16021469 NCBI chr 9:11,547,533...11,573,935
Ensembl chr 9:11,547,531...11,567,790
JBrowse link
G Mocs2 molybdenum cofactor synthesis 2 involved_in ISS
ISO
GO_REF:0000024
(PMID:10053004), (PMID:12732628), (PMID:15073332), (PMID:16021469)
(PMID:12732628), (PMID:15073332), (PMID:16021469)
(PMID:10053004), (PMID:12732628), (PMID:16021469)
UniProt
RGD
PMID:10053004 PMID:12732628 PMID:15073332 PMID:16021469 GO_REF:0000024 NCBI chr 2:46,504,574...46,516,327
Ensembl chr 2:46,504,588...46,516,324
JBrowse link
G Mocs3 molybdenum cofactor synthesis 3 involved_in ISO (PMID:15073332) RGD PMID:15073332 NCBI chr 3:156,939,763...156,941,723
Ensembl chr 3:156,939,809...156,941,890
JBrowse link
G Nfs1 NFS1 cysteine desulfurase involved_in IEA GO_REF:0000043 UniProt GO_REF:0000043 NCBI chr 3:144,637,309...144,659,660
Ensembl chr 3:144,637,309...144,659,666
JBrowse link
molybdopterin cofactor biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gphn gephyrin involved_in ISO
IBA
IEA
(PMID:26613940), (PMID:9990024)
PMID:21873635
GO_REF:0000104
RGD
UniProt
PMID:9990024 PMID:26613940 PMID:21873635 GO_REF:0000104, RGD:13792537 NCBI chr 6:96,954,365...97,483,617
Ensembl chr 6:96,892,148...97,483,612
JBrowse link
G Mocs1 molybdenum cofactor synthesis 1 acts_upstream_of_or_within ISO MGI:2659140 (MGI:2447229|PMID:12471057), (MGI:3576970|PMID:15862276), (MGI:3757917|PMID:17236133) RGD PMID:12471057 PMID:15862276 PMID:17236133 MGI:2447229 MGI:3576970 MGI:3757917 NCBI chr 9:11,547,533...11,573,935
Ensembl chr 9:11,547,531...11,567,790
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      prosthetic group metabolic process 6
        molybdopterin cofactor metabolic process 6
          Mo-molybdopterin cofactor metabolic process + 6
          W-molybdopterin cofactor metabolic process + 0
          molybdopterin cofactor biosynthetic process 2
          molybdopterin cofactor catabolic process + 0
Path 2
Term Annotations click to browse term
  biological_process 19834
    metabolic process 12042
      organic substance metabolic process 11568
        macromolecule metabolic process 9999
          protein metabolic process 6042
            cellular protein metabolic process 5369
              prosthetic group metabolic process 6
                molybdopterin cofactor metabolic process 6
                  Mo-molybdopterin cofactor metabolic process + 6
                  W-molybdopterin cofactor metabolic process + 0
                  molybdopterin cofactor biosynthetic process 2
                  molybdopterin cofactor catabolic process + 0
paths to the root