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ONTOLOGY REPORT - ANNOTATIONS


Term:protein serine/threonine kinase activator activity
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Accession:GO:0043539 term browser browse the term
Definition:Binds to and increases the activity of a protein serine/threonine kinase.
Synonyms:exact_synonym: protein ser/thr kinase activator activity


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protein serine/threonine kinase activator activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 ISO
ISS
(PMID:16049005)
GO_REF:0000024
RGD
UniProt
PMID:16049005 GO_REF:0000024 NCBI chr 9:65,961,361...66,034,396
Ensembl chr 9:65,961,346...66,033,871
JBrowse link
G Cab39 calcium binding protein 39 ISO
IBA
(PMID:19892943), (PMID:24393035)
PMID:21873635
RGD PMID:19892943, PMID:24393035, PMID:21873635 RGD:13792537 NCBI chr 9:92,834,327...92,895,778
Ensembl chr 9:92,834,357...92,895,778
JBrowse link
G Cab39l calcium binding protein 39-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr15:39,745,124...39,849,022
Ensembl chr15:39,759,257...39,870,208
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 IDA
ISO
(PMID:12832520)
PMID:15994305
RGD PMID:12832520, PMID:8662984, PMID:15994305 RGD:632374, RGD:8553752 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Dazap2 DAZ associated protein 2 IEA
ISO
GO_REF:0000107
(MGI:MGI:6148351|PMID:18762249)
Ensembl
RGD
PMID:18762249 GO_REF:0000107, MGI:MGI:6148351 NCBI chr 7:142,238,780...142,244,301
Ensembl chr 7:142,239,035...142,243,241
JBrowse link
G Dbf4 DBF4 zinc finger IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 4:22,898,527...22,914,091
Ensembl chr 4:22,898,527...22,914,177
JBrowse link
G Ddx3x DEAD-box helicase 3, X-linked ISO (PMID:23413191) RGD PMID:23413191 NCBI chr  X:10,400,363...10,414,010
Ensembl chr  X:10,400,366...10,413,995
JBrowse link
G Dele1 DAP3 binding cell death enhancer 1 ISO
ISS
(PMID:32132706), (PMID:32132707)
GO_REF:0000024
RGD
UniProt
PMID:32132706, PMID:32132707 GO_REF:0000024 NCBI chr18:31,396,897...31,409,914
Ensembl chr18:31,396,922...31,409,907
JBrowse link
G Etaa1 ETAA1 activator of ATR kinase ISO
IBA
(PMID:27723717), (PMID:27723720)
PMID:21873635
RGD PMID:27723717, PMID:27723720, PMID:21873635 RGD:13792537 NCBI chr14:102,290,655...102,293,674
Ensembl chr14:102,290,418...102,293,677
JBrowse link
G Fam20a FAM20A, golgi associated secretory pathway pseudokinase ISO
IBA
(PMID:25789606)
PMID:21873635
RGD PMID:25789606, PMID:21873635 RGD:13792537 NCBI chr10:97,962,467...98,017,171
Ensembl chr10:97,962,693...98,018,014
JBrowse link
G Igf1 insulin-like growth factor 1 IDA PMID:17023532 BHF-UCL PMID:17023532 RGD:1600072 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Igf2 insulin-like growth factor 2 ISO
IBA
IEA
(MGI:MGI:4438697|PMID:20032056)
PMID:21873635
GO_REF:0000107
RGD
Ensembl
PMID:20032056, PMID:21873635 GO_REF:0000107, MGI:MGI:4438697, RGD:13792537 NCBI chr 1:215,828,102...215,839,081
Ensembl chr 1:215,828,102...215,846,911
JBrowse link
G Incenp inner centromere protein IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:225,923,448...225,953,384
Ensembl chr 1:225,925,773...225,952,516
JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 ISO (PMID:17563371) RGD PMID:17563371 NCBI chr 1:142,525,041...142,615,673
Ensembl chr 1:142,525,046...142,615,673
JBrowse link
G Irgm immunity-related GTPase M ISO (PMID:28389568) RGD PMID:28389568 NCBI chr10:34,213,885...34,221,968
Ensembl chr10:34,213,936...34,221,928
JBrowse link
G Lgals9 galectin 9 ISO (MGI:MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:MGI:5688819 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Ltf lactotransferrin ISO (PMID:20345905) RGD PMID:20345905 NCBI chr 8:119,290,416...119,313,261
Ensembl chr 8:119,290,416...119,313,261
JBrowse link
G Map2k1 mitogen activated protein kinase kinase 1 IEA
ISO
GO_REF:0000107
(PMID:8388392)
Ensembl
RGD
PMID:8388392 GO_REF:0000107 NCBI chr 8:69,134,218...69,722,573
Ensembl chr 8:69,134,223...69,164,758
JBrowse link
G Map2k2 mitogen activated protein kinase kinase 2 ISO (PMID:8388392) RGD PMID:8388392 NCBI chr 7:11,458,971...11,478,520
Ensembl chr 7:11,458,967...11,478,489
JBrowse link
G Mlst8 MTOR associated protein, LST8 homolog ISO
IEA
(PMID:12718876)
GO_REF:0000107
RGD
Ensembl
PMID:12718876 GO_REF:0000107 NCBI chr10:13,839,250...13,845,001
Ensembl chr10:13,839,250...13,845,001
JBrowse link
G Mtcp1 mature T-cell proliferation 1 ISO
IBA
(PMID:10983986)
PMID:21873635
RGD PMID:10983986, PMID:21873635 RGD:13792537 NCBI chr18:411,159...411,934
Ensembl chr18:411,455...411,849
JBrowse link
G P2rx7 purinergic receptor P2X 7 IMP
IC
Akt (protein kinase B); Ser473, Thr308
Akt (protein kinase B); involves Ser473, Thr308 phosphorylation
RGD PMID:15023862, PMID:15023862 RGD:1642719, RGD:1642719 NCBI chr12:39,353,613...39,396,042
Ensembl chr12:39,353,613...39,396,042
JBrowse link
G Parp16 poly (ADP-ribose) polymerase family, member 16 IEA
IBA
ISO
GO_REF:0000107
PMID:21873635
(PMID:23103912)
Ensembl
RGD
PMID:23103912, PMID:21873635 GO_REF:0000107, RGD:13792537 NCBI chr 8:70,712,393...70,731,212
Ensembl chr 8:70,708,873...70,729,985
JBrowse link
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase ISO (PMID:16186805) RGD PMID:16186805 NCBI chr20:8,165,423...8,169,557
Ensembl chr20:8,165,307...8,169,555
JBrowse link
G Spry2 sprouty RTK signaling antagonist 2 ISO (PMID:18070883) RGD PMID:18070883 NCBI chr15:90,172,769...90,177,823
Ensembl chr15:90,172,975...90,175,802
JBrowse link
G Strada STE20 related adaptor alpha ISO
IEA
(PMID:19892943)
GO_REF:0000107
RGD
Ensembl
PMID:19892943 GO_REF:0000107 NCBI chr10:94,355,369...94,384,404
Ensembl chr10:94,355,384...94,384,339
JBrowse link
G Taok1 TAO kinase 1 IDA PMID:14517247 ARUK-UCL PMID:14517247 RGD:8553906 NCBI chr10:62,542,870...62,630,341
Ensembl chr10:62,566,732...62,630,155
JBrowse link
G Tcl1a Tcl1 family Akt coactivator A ISO
IBA
(PMID:10983986)
PMID:21873635
RGD PMID:10983986, PMID:21873635 RGD:13792537 NCBI chr 6:128,888,768...128,894,761
Ensembl chr 6:128,888,768...128,894,761
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (MGI:MGI:5688819|PMID:25065622) RGD PMID:25065622 MGI:MGI:5688819 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
cyclin-dependent protein serine/threonine kinase activator activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07049223.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 5:110,831,936...110,832,175 JBrowse link
G AC112018.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 4:142,970,009...142,970,245 JBrowse link
G Ccnb1 cyclin B1 ISO (PMID:24746669) RGD PMID:24746669 NCBI chr 2:30,782,133...30,791,106
Ensembl chr 2:30,783,915...30,791,221
JBrowse link
G Ccnk cyclin K IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 6:132,090,235...132,113,560
Ensembl chr 6:132,090,218...132,113,557
JBrowse link
G Ccnt1 cyclin T1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:140,215,052...140,245,958
Ensembl chr 7:140,219,551...140,245,723
JBrowse link
G Ccnt2 cyclin T2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:44,475,959...44,516,892
Ensembl chr13:44,475,970...44,515,739
JBrowse link
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 IDA
ISO
MGI:MGI:1931885 (MGI:MGI:2149271|PMID:11517264) RGD PMID:11517264, PMID:8662984 MGI:MGI:2149271, RGD:632374 NCBI chr10:67,862,054...67,863,255
Ensembl chr10:67,862,054...67,863,255
JBrowse link
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 ISO MGI:MGI:2387662 (MGI:MGI:2149271|PMID:11517264), (MGI:MGI:6158991|PMID:10683146) RGD PMID:10683146, PMID:11517264 MGI:MGI:2149271, MGI:MGI:6158991 NCBI chr 9:82,120,059...82,121,527
Ensembl chr 9:82,120,059...82,121,527
JBrowse link
G Cks1b CDC28 protein kinase regulatory subunit 1B IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 2:188,740,564...188,745,144
Ensembl chr 2:188,740,573...188,745,144
JBrowse link
G Cks1l CDC28 protein kinase regulatory subunit 1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:110,831,843...110,832,242 JBrowse link
G Cks2 CDC28 protein kinase regulatory subunit 2 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr17:13,587,664...13,593,423
Ensembl chr17:13,587,665...13,593,423
JBrowse link
G LOC103692976 cyclin-T1-like IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 7:140,149,991...140,172,615
Ensembl chr 7:140,154,490...140,172,448
JBrowse link
G Mnat1 MNAT1 component of CDK activating kinase IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 6:95,995,341...96,153,331
Ensembl chr 6:96,007,805...96,153,330
JBrowse link
eukaryotic elongation factor-2 kinase activator activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 NAS PMID:12194824 UniProt PMID:12194824 RGD:8553742 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  molecular_function 20457
    molecular function regulator 3479
      enzyme regulator activity 1018
        enzyme activator activity 467
          kinase activator activity 96
            protein kinase activator activity 90
              protein serine/threonine kinase activator activity 42
                cyclin-dependent protein serine/threonine kinase activator activity 13
                eukaryotic elongation factor-2 kinase activator activity 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.