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ONTOLOGY REPORT - ANNOTATIONS


Term:skeletal muscle adaptation
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Accession:GO:0043501 term browser browse the term
Definition:Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.
Synonyms:related_synonym: skeletal muscle plasticity


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skeletal muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1s calcium voltage-gated channel subunit alpha1 S acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3616422|PMID:2419767) MGI
Ensembl
PMID:2419767 GO_REF:0000107 MGI:3616422 NCBI chrNW_004936567:3,269,283...3,331,858
Ensembl chrNW_004936567:3,269,355...3,331,460
JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 ISO RGD PMID:24284598 RGD:329337337 NCBI chrNW_004936616:484,062...584,950
Ensembl chrNW_004936616:484,045...587,891
JBrowse link
negative regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbp5 insulin like growth factor binding protein 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936586:647,553...666,595
Ensembl chrNW_004936586:647,493...666,621
JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase ISO RGD PMID:23470307 RGD:10041029 NCBI chrNW_004936474:158,376...282,310
Ensembl chrNW_004936474:157,590...282,342
JBrowse link
G Mymk myomaker, myoblast fusion factor involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936669:3,404,729...3,413,123
Ensembl chrNW_004936669:3,404,704...3,413,136
JBrowse link
regulation of skeletal muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmya5 cardiomyopathy associated 5 acts_upstream_of_or_within ISO (MGI:5056263|PMID:21427212) MGI PMID:21427212 MGI:5056263 NCBI chrNW_004936549:7,468,393...7,555,433 JBrowse link
skeletal muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:3,033,854...3,046,364
Ensembl chrNW_004936599:3,029,202...3,046,385
JBrowse link
G Asb2 ankyrin repeat and SOCS box containing 2 involved_in ISO (MGI:6716965|PMID:27182554) UniProt PMID:27182554 MGI:6716965 NCBI chrNW_004936733:1,813,569...1,849,805
Ensembl chrNW_004936733:1,813,548...1,849,806
JBrowse link
G Cflar CASP8 and FADD like apoptosis regulator involved_in ISO (MGI:5707584|PMID:21364645) BHF-UCL PMID:21364645 MGI:5707584 NCBI chrNW_004936726:381,888...425,565
Ensembl chrNW_004936726:381,835...423,311
JBrowse link
G Il15 interleukin 15 ISO RGD PMID:17135303 RGD:1626613 NCBI chrNW_004936535:6,344,348...6,358,803
Ensembl chrNW_004936535:6,344,395...6,350,197
JBrowse link
G Ireb2 iron responsive element binding protein 2 ISO RGD PMID:23994517 RGD:12904021 NCBI chrNW_004936471:36,547,552...36,601,327
Ensembl chrNW_004936471:36,547,500...36,600,636
JBrowse link
G Mstn myostatin ISO RGD PMID:15758361 RGD:2303594 NCBI chrNW_004936506:7,988,879...7,996,260
Ensembl chrNW_004936506:7,988,718...7,996,971
JBrowse link
G Myod1 myogenic differentiation 1 ISO RGD PMID:12839833 RGD:1302305 NCBI chrNW_004936528:1,407,187...1,409,683
Ensembl chrNW_004936528:1,407,661...1,409,573
JBrowse link
G Myog myogenin ISO RGD PMID:12839833 RGD:1302305 NCBI chrNW_004936567:1,507,042...1,509,814
Ensembl chrNW_004936567:1,507,042...1,509,815
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha ISO RGD PMID:16870628 RGD:10053649 NCBI chrNW_004936477:4,881,230...5,488,208
Ensembl chrNW_004936477:5,199,881...5,488,226
JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 ISO RGD PMID:17885021 RGD:1642984 NCBI chrNW_004936490:3,441,046...3,492,917
Ensembl chrNW_004936490:3,441,055...3,492,917
JBrowse link
G Trim63 tripartite motif containing 63 ISO RGD PMID:11679633 RGD:633893 NCBI chrNW_004936474:10,598,571...10,610,197
Ensembl chrNW_004936474:10,598,561...10,633,001
JBrowse link
skeletal muscle fiber adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta1 actin alpha 1, skeletal muscle ISO RGD PMID:16428321 RGD:1598721 NCBI chrNW_004936484:20,236,320...20,239,385
Ensembl chrNW_004936484:20,236,320...20,239,430
JBrowse link
G Myod1 myogenic differentiation 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3840749|PMID:19319192) MGI
Ensembl
PMID:19319192 GO_REF:0000107 MGI:3840749 NCBI chrNW_004936528:1,407,187...1,409,683
Ensembl chrNW_004936528:1,407,661...1,409,573
JBrowse link
G Myoz1 myozenin 1 acts_upstream_of_or_within_positive_effect
involved_in
ISO
IEA
(MGI:3831256|PMID:18846255) BHF-UCL
Ensembl
PMID:18846255 GO_REF:0000107 MGI:3831256 NCBI chrNW_004936521:5,420,553...5,428,470
Ensembl chrNW_004936521:5,420,317...5,428,466
JBrowse link
G Myoz2 myozenin 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936869:244,599...284,228
Ensembl chrNW_004936869:244,591...284,194
JBrowse link
skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor ISO RGD PMID:7957162 RGD:10043318 NCBI chrNW_004936635:485,903...647,820
Ensembl chrNW_004936635:485,903...647,932
JBrowse link
G Myoc myocilin involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936481:15,544,733...15,556,813
Ensembl chrNW_004936481:15,544,660...15,556,857
JBrowse link
transition between fast and slow fiber term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936599:3,033,854...3,046,364
Ensembl chrNW_004936599:3,029,202...3,046,385
JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829334|PMID:18978355) MGI
Ensembl
PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chrNW_004936558:3,300,941...3,357,595
Ensembl chrNW_004936558:3,300,941...3,357,941
JBrowse link
G LOC101972165 myosin-7 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829334|PMID:18978355) MGI
Ensembl
PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chrNW_004936722:967,443...991,530
Ensembl chrNW_004936722:969,384...991,129
JBrowse link
G LOC101973730 general transcription factor II-I repeat domain-containing protein 2B involved_in IEA Ensembl GO_REF:0000107 NCBI chrNW_004936543:3,631,403...3,657,569 JBrowse link
G Nfatc1 nuclear factor of activated T cells 1 acts_upstream_of_or_within ISO (MGI:3829530|PMID:18408153) MGI PMID:18408153 MGI:3829530 NCBI chrNW_004936616:484,062...584,950
Ensembl chrNW_004936616:484,045...587,891
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5056263|PMID:21427212) MGI
Ensembl
PMID:21427212 GO_REF:0000107 MGI:5056263 NCBI chrNW_004936520:1,987,989...2,146,473
Ensembl chrNW_004936520:1,987,045...2,146,540
JBrowse link
G Tead1 TEA domain transcription factor 1 acts_upstream_of_or_within ISO (MGI:3829334|PMID:18978355) MGI PMID:18978355 MGI:3829334 NCBI chrNW_004936528:5,607,993...5,774,161
Ensembl chrNW_004936528:5,607,987...5,856,678
JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829334|PMID:18978355) MGI
Ensembl
PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chrNW_004936473:3,290,961...3,293,920
Ensembl chrNW_004936473:3,290,913...3,294,132
JBrowse link
G Tnni1 troponin I1, slow skeletal type acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829334|PMID:18978355) MGI
Ensembl
PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chrNW_004936567:3,013,359...3,025,137
Ensembl chrNW_004936567:3,013,342...3,025,171
JBrowse link
G Tnnt1 troponin T1, slow skeletal type acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:3829334|PMID:18978355) MGI
Ensembl
PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chrNW_004936886:425,331...434,546
Ensembl chrNW_004936886:425,438...435,500
JBrowse link
transition between slow and fast fiber term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2i general transcription factor IIi acts_upstream_of_or_within ISO (MGI:5504578|PMID:22899722) MGI PMID:22899722 MGI:5504578 NCBI chrNW_004936543:3,521,763...3,611,410
Ensembl chrNW_004936543:3,518,462...3,611,452
JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 acts_upstream_of_or_within
involved_in
ISO
IEA
(MGI:5504578|PMID:22899722) MGI
Ensembl
PMID:22899722 GO_REF:0000107 MGI:5504578 NCBI chrNW_004936543:3,435,039...3,483,202
Ensembl chrNW_004936543:3,435,072...3,483,246
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15868
    response to stimulus 8526
      muscle adaptation 145
        striated muscle adaptation 61
          skeletal muscle adaptation 32
            regulation of skeletal muscle adaptation + 16
            skeletal muscle atrophy 11
            skeletal muscle fiber adaptation 4
            skeletal muscle hypertrophy + 5
Path 2
Term Annotations click to browse term
  biological_process 15868
    multicellular organismal process 7714
      system process 2573
        muscle system process 456
          muscle adaptation 145
            striated muscle adaptation 61
              skeletal muscle adaptation 32
                regulation of skeletal muscle adaptation + 16
                skeletal muscle atrophy 11
                skeletal muscle fiber adaptation 4
                skeletal muscle hypertrophy + 5
paths to the root