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ONTOLOGY REPORT - ANNOTATIONS

Term:skeletal muscle adaptation
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Accession:GO:0043501 term browser browse the term
Definition:Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.
Synonyms:related_synonym: skeletal muscle plasticity

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skeletal muscle adaptation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1s calcium voltage-gated channel subunit alpha1 S ISO MGI:1856326 (MGI:3616422|PMID:2419767) RGD PMID:2419767 MGI:3616422 NCBI chr13:52,889,570...52,964,558
Ensembl chr13:52,889,737...52,964,155 		JBrowse link
negative regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbp5 insulin-like growth factor binding protein 5 ISO (MGI:3039207|PMID:15010534) RGD PMID:15010534 MGI:3039207 NCBI chr 9:80,154,230...80,166,813
Ensembl chr 9:80,150,211...80,167,033 		JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23470307 RGD:10041029 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967 		JBrowse link
G Mymk myomaker, myoblast fusion factor ISO (MGI:6116777|PMID:28186492) RGD PMID:28186492 MGI:6116777 NCBI chr 3:5,608,243...5,617,689
Ensembl chr 3:5,608,243...5,617,225 		JBrowse link
regulation of skeletal muscle adaptation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmya5 cardiomyopathy associated 5 ISO MGI:107164 (MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:5056263 NCBI chr 2:22,646,694...22,744,536
Ensembl chr 2:22,646,712...22,744,407 		JBrowse link
skeletal muscle atrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 ISO (MGI:5554485|PMID:24234654) RGD PMID:24234654 MGI:5554485 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator ISO (MGI:5707584|PMID:21364645) RGD PMID:21364645 MGI:5707584 NCBI chr 9:65,534,608...65,586,395
Ensembl chr 9:65,534,704...65,587,251 		JBrowse link
G Il15 interleukin 15 IEP RGD PMID:17135303 RGD:1626613 NCBI chr19:23,542,606...23,624,366
Ensembl chr19:23,542,889...23,554,594 		JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP RGD PMID:23994517 RGD:12904021 NCBI chr 8:59,450,974...59,503,634
Ensembl chr 8:59,420,123...59,501,118 		JBrowse link
G Mstn myostatin IEP RGD PMID:15758361 RGD:2303594 NCBI chr 9:53,310,977...53,315,804
Ensembl chr 9:53,309,598...53,315,915 		JBrowse link
G Myod1 myogenic differentiation 1 IEP RGD PMID:12839833 RGD:1302305 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248 		JBrowse link
G Myog myogenin IEP RGD PMID:12839833 RGD:1302305 NCBI chr13:51,126,459...51,129,048
Ensembl chr13:51,126,459...51,129,048 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:16870628 RGD:10053649 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP RGD PMID:17885021 RGD:1642984 NCBI chr10:73,824,200...73,865,503
Ensembl chr10:73,824,202...73,865,364 		JBrowse link
G Trim63 tripartite motif containing 63 IEP RGD PMID:11679633 RGD:633893 NCBI chr 5:152,533,362...152,547,138
Ensembl chr 5:152,533,349...152,547,179 		JBrowse link
skeletal muscle fiber adaptation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta1 actin, alpha 1, skeletal muscle IEP RGD PMID:16428321 RGD:1598721 NCBI chr19:56,674,072...56,677,084
Ensembl chr19:56,674,074...56,677,084 		JBrowse link
G Myod1 myogenic differentiation 1 IEA
ISO		 GO_REF:0000107
(MGI:3840749|PMID:19319192)		 Ensembl
RGD		 PMID:19319192 GO_REF:0000107 MGI:3840749 NCBI chr 1:102,396,538...102,399,248
Ensembl chr 1:102,396,538...102,399,248 		JBrowse link
G Myoz1 myozenin 1 ISO (MGI:3831256|PMID:18846255) RGD PMID:18846255 MGI:3831256 NCBI chr15:4,077,066...4,084,306
Ensembl chr15:4,077,091...4,084,314 		JBrowse link
G Myoz2 myozenin 2 ISO (MGI:3513659|PMID:15543153) RGD PMID:15543153 MGI:3513659 NCBI chr 2:227,180,887...227,207,629
Ensembl chr 2:227,180,886...227,207,635 		JBrowse link
skeletal muscle hypertrophy term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IMP RGD PMID:7957162 RGD:10043318 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026 		JBrowse link
G Myoc myocilin IEA
ISO
ISS		 GO_REF:0000107
(MGI:5320812|PMID:22371502)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:22371502 GO_REF:0000024 GO_REF:0000107 MGI:5320812 NCBI chr13:80,517,531...80,527,928
Ensembl chr13:80,517,536...80,527,928 		JBrowse link
transition between fast and slow fiber term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 ISO (MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:3759354 NCBI chr 1:220,120,532...220,136,460
Ensembl chr 1:220,120,533...220,136,470 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 ISO (MGI:3829334|PMID:18978355) RGD PMID:18978355 MGI:3829334 NCBI chr12:39,553,903...39,603,326
Ensembl chr12:39,553,903...39,603,326 		JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 ISO (MGI:5504578|PMID:22899722) RGD PMID:22899722 MGI:5504578 NCBI chr12:25,509,059...25,555,554
Ensembl chr12:25,509,653...25,546,200 		JBrowse link
G Myh7 myosin heavy chain 7 IEA
ISO		 GO_REF:0000107
(MGI:3829334|PMID:18978355)		 Ensembl
RGD		 PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chr15:33,605,769...33,657,761
Ensembl chr15:33,634,422...33,656,089 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 ISO (MGI:3829530|PMID:18408153) RGD PMID:18408153 MGI:3829530 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO (MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:5056263 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854 		JBrowse link
G Tead1 TEA domain transcription factor 1 ISO (MGI:3829334|PMID:18978355) RGD PMID:18978355 MGI:3829334 NCBI chr 1:177,495,500...177,714,795
Ensembl chr 1:177,495,782...177,707,061 		JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type ISO (MGI:3829334|PMID:18978355) RGD PMID:18978355 MGI:3829334 NCBI chr16:7,292,207...7,295,238
Ensembl chr16:7,292,096...7,295,465 		JBrowse link
G Tnni1 troponin I1, slow skeletal type IEA
ISO		 GO_REF:0000107
(MGI:3829334|PMID:18978355)		 Ensembl
RGD		 PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chr13:52,624,856...52,637,297
Ensembl chr13:52,624,878...52,637,297 		JBrowse link
G Tnnt1 troponin T1, slow skeletal type ISO (MGI:3829334|PMID:18978355) RGD PMID:18978355 MGI:3829334 NCBI chr 1:72,889,270...72,899,629
Ensembl chr 1:72,889,270...72,899,659 		JBrowse link
transition between slow and fast fiber term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2i general transcription factor II I ISO (MGI:5504578|PMID:22899722) RGD PMID:22899722 MGI:5504578 NCBI chr12:25,410,804...25,487,970
Ensembl chr12:25,411,207...25,488,156 		JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 ISO (MGI:5504578|PMID:22899722) RGD PMID:22899722 MGI:5504578 NCBI chr12:25,264,052...25,370,947
Ensembl chr12:25,264,192...25,371,001 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20045
    response to stimulus 10558
      muscle adaptation 140
        striated muscle adaptation 56
          skeletal muscle adaptation 31
            regulation of skeletal muscle adaptation + 16
            skeletal muscle atrophy 10
            skeletal muscle fiber adaptation 4
            skeletal muscle hypertrophy + 5
Path 2
Term Annotations click to browse term
  biological_process 20045
    multicellular organismal process 9042
      system process 3454
        muscle system process 460
          muscle adaptation 140
            striated muscle adaptation 56
              skeletal muscle adaptation 31
                regulation of skeletal muscle adaptation + 16
                skeletal muscle atrophy 10
                skeletal muscle fiber adaptation 4
                skeletal muscle hypertrophy + 5
paths to the root