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ONTOLOGY REPORT - ANNOTATIONS

Term:muscle adaptation
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Accession:GO:0043500 term browser browse the term
Definition:A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
Synonyms:related_synonym: muscle plasticity


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cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5576864|PMID:24137001)
GO_REF:0000107		 RGD
Ensembl		 PMID:24137001 GO_REF:0000107 MGI:5576864 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Bmp2 bone morphogenetic protein 2 IMP RGD PMID:26873969 RGD:11526363 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmp4 bone morphogenetic protein 4 IMP RGD PMID:26873969 RGD:11526363 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Camta2 calmodulin binding transcription activator 2 acts_upstream_of_or_within ISO (PMID:16678093) RGD PMID:16678093 NCBI chr10:55,383,450...55,401,838
Ensembl chr10:55,383,450...55,401,558 		JBrowse link
G Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit acts_upstream_of_or_within ISO (MGI:5576864|PMID:24137001) RGD PMID:24137001 MGI:5576864 NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:3054171|MGI:3778685 (MGI:5002493|PMID:20705924) RGD PMID:20705924 MGI:5002493 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gata6 GATA binding protein 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3054171|MGI:3654150 (MGI:5002493|PMID:20705924)		 Ensembl
RGD		 PMID:20705924 GO_REF:0000107 MGI:5002493 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO (MGI:3624193|PMID:16603706) RGD PMID:16603706 MGI:3624193 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Inpp5f inositol polyphosphate-5-phosphatase F acts_upstream_of_or_within ISO MGI:4128518 (MGI:4943859|PMID:19875726) RGD PMID:19875726 MGI:4943859 NCBI chr 1:183,190,480...183,270,276
Ensembl chr 1:183,190,480...183,270,276 		JBrowse link
G Kdm4a lysine demethylase 4A acts_upstream_of_or_within ISO (MGI:5050547|PMID:21555854) RGD PMID:21555854 MGI:5050547 NCBI chr 5:131,672,754...131,719,534
Ensembl chr 5:131,672,754...131,719,501 		JBrowse link
G Klf15 KLF transcription factor 15 involved_in ISO (MGI:3709247|PMID:17438289) RGD PMID:17438289 MGI:3709247 NCBI chr 4:122,965,718...122,978,403
Ensembl chr 4:122,965,807...122,978,374 		JBrowse link
G Mef2c myocyte enhancer factor 2C acts_upstream_of_or_within ISO (MGI:1346950|PMID:10531040) RGD PMID:10531040 MGI:1346950 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mir208b microRNA 208b acts_upstream_of_or_within ISO (MGI:5576864|PMID:24137001) RGD PMID:24137001 MGI:5576864 NCBI chr15:28,451,638...28,451,749
Ensembl chr15:28,451,638...28,451,749 		JBrowse link
G Myh6 myosin heavy chain 6 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:5576864|PMID:24137001)		 Ensembl
RGD		 PMID:24137001 GO_REF:0000107 MGI:5576864 NCBI chr15:28,418,120...28,442,316
Ensembl chr15:28,417,616...28,441,720 		JBrowse link
G Myh7 myosin heavy chain 7 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5576864|PMID:24137001)
GO_REF:0000107		 RGD
Ensembl		 PMID:24137001 GO_REF:0000107 MGI:5576864 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Nfatc3 nuclear factor of activated T-cells 3 acts_upstream_of_or_within ISO MGI:107164 (MGI:2388546|PMID:12370307) RGD PMID:12370307 MGI:2388546 NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150 		JBrowse link
G Nppa natriuretic peptide A acts_upstream_of_or_within ISO MGI:1857231 (MGI:3606834|PMID:14985074), (MGI:3610438|PMID:15452027), (MGI:5576864|PMID:24137001)
MGI:1857231 (MGI:5816190|PMID:26536903)		 RGD PMID:14985074 PMID:15452027 PMID:24137001 PMID:26536903 MGI:3606834 MGI:3610438 MGI:5576864 MGI:5816190 NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351 		JBrowse link
G Nppb natriuretic peptide B acts_upstream_of_or_within ISO (MGI:5576864|PMID:24137001) RGD PMID:24137001 MGI:5576864 NCBI chr 5:158,416,813...158,418,175
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha acts_upstream_of_or_within ISO MGI:103296 (MGI:2388546|PMID:12370307) RGD PMID:12370307 MGI:2388546 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Smad1 SMAD family member 1 IMP RGD PMID:26873969 RGD:11526363 NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651 		JBrowse link
G Smad4 SMAD family member 4 IMP RGD PMID:26873969 RGD:11526363 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Tcap titin-cap involved_in ISO (PMID:12507422) RGD PMID:12507422 NCBI chr10:83,381,719...83,382,887
Ensembl chr10:83,381,719...83,382,887 		JBrowse link
muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo32 F-box protein 32 IDA RGD PMID:11679633 RGD:633893 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Gatm glycine amidinotransferase involved_in IEA
ISO		 GO_REF:0000107
(PMID:26490222)		 Ensembl
RGD		 PMID:26490222 GO_REF:0000107 NCBI chr 3:109,658,919...109,675,508
Ensembl chr 3:109,658,951...109,684,129 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IEP RGD PMID:17622304 RGD:4892297 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Psmb9 proteasome 20S subunit beta 9 IEP RGD PMID:14678786 RGD:9854636 NCBI chr20:4,667,044...4,672,512
Ensembl chr20:4,666,046...4,672,512 		JBrowse link
G Tbce tubulin folding cofactor E acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1856997 (MGI:77306|PMID:7472523)
GO_REF:0000107		 RGD
Ensembl		 PMID:7472523 GO_REF:0000107 MGI:77306 NCBI chr17:51,290,143...51,336,090
Ensembl chr17:51,290,202...51,336,089 		JBrowse link
negative regulation of cardiac muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Oga O-GlcNAcase IMP RGD PMID:17573462 RGD:2305953 NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359 		JBrowse link
negative regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Akap1 A-kinase anchoring protein 1 IMP RGD PMID:19358331 RGD:2312604 NCBI chr10:73,621,021...73,654,123
Ensembl chr10:73,621,883...73,653,896 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3695247|PMID:16798733)		 Ensembl
RGD		 PMID:16798733 GO_REF:0000107 MGI:3695247 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Cav3 caveolin 3 involved_in
acts_upstream_of_or_within		 ISO (PMID:12847114)
MGI:2180558 (MGI:3804582|PMID:18552160)		 RGD PMID:12847114 PMID:18552160 MGI:3804582 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Fbxo32 F-box protein 32 involved_in IMP PMID:24117217 BHF-UCL PMID:24117217 RGD:11079185 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (MGI:5286818|PMID:21633169) RGD PMID:21633169 MGI:5286818 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Gdf1 growth differentiation factor 1 IMP RGD PMID:24275554 RGD:11252017 NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519 		JBrowse link
G Glrx3 glutaredoxin 3 involved_in ISO (MGI:4461873|PMID:18258855) RGD PMID:18258855 MGI:4461873 NCBI chr 1:192,241,707...192,272,012
Ensembl chr 1:192,241,701...192,272,010 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta acts_upstream_of_or_within ISO (MGI:2157270|PMID:11782539) RGD PMID:11782539 MGI:2157270 NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Jarid2 jumonji and AT-rich interaction domain containing 2 involved_in IGI
IMP		 PMID:24657879 BHF-UCL PMID:24657879 PMID:24657879 RGD:11344938, RGD:11344938 NCBI chr17:19,777,487...19,957,696
Ensembl chr17:19,777,266...19,955,690 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 IMP RGD PMID:28679649 RGD:329955564 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
G Mir1 microRNA 1 involved_in ISO (PMID:19933931) RGD PMID:19933931 NCBI chr18:1,887,537...1,887,623 JBrowse link
G Mir1b microRNA 1b involved_in ISO (PMID:19933931) RGD PMID:19933931 NCBI chr 3:167,487,117...167,487,201
Ensembl chr 3:167,487,117...167,487,201 		JBrowse link
G Mlip muscular LMNA-interacting protein involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
(MGI:5581934|PMID:22343712)		 UniProt
RGD		 PMID:22343712 GO_REF:0000024 MGI:5581934 NCBI chr 8:77,935,087...78,204,725
Ensembl chr 8:77,935,079...78,204,254 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G P2rx4 purinergic receptor P2X 4 involved_in ISO (PMID:15130891) RGD PMID:15130891 NCBI chr12:33,844,609...33,862,265
Ensembl chr12:33,844,396...33,862,253 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 involved_in ISO (MGI:3836877|PMID:19127022) RGD PMID:19127022 MGI:3836877 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3689643|PMID:16151019)		 Ensembl
RGD		 PMID:16151019 GO_REF:0000107 MGI:3689643 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO UniProtKB:P25119 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:P25118 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Trim63 tripartite motif containing 63 involved_in IMP PMID:24117217 BHF-UCL PMID:24117217 RGD:11079185 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322 		JBrowse link
negative regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 involved_in ISO (PMID:19287093)
(MGI:3848765|PMID:19287093)		 RGD PMID:19287093 MGI:3848765 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246 		JBrowse link
G Errfi1 ERBB receptor feedback inhibitor 1 IDA RGD PMID:19204184 RGD:9685562 NCBI chr 5:161,323,981...161,337,289
Ensembl chr 5:161,323,998...161,337,282 		JBrowse link
G Foxo1 forkhead box O1 involved_in IMP PMID:26436652 UniProt PMID:26436652 RGD:13210548 NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790 		JBrowse link
G Lmna lamin A/C involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5700584|PMID:26436652)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:26436652 GO_REF:0000024 GO_REF:0000107 MGI:5700584 NCBI chr 2:173,939,751...173,960,423
Ensembl chr 2:173,939,751...173,960,423 		JBrowse link
G Mlip muscular LMNA-interacting protein involved_in ISO (MGI:5700584|PMID:26436652), (MGI:5908525|PMID:26359501) RGD PMID:26359501 PMID:26436652 MGI:5700584 MGI:5908525 NCBI chr 8:77,935,087...78,204,725
Ensembl chr 8:77,935,079...78,204,254 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma acts_upstream_of_or_within IDA PMID:29695452 BHF-UCL PMID:29695452 RGD:150521636 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Smad3 SMAD family member 3 involved_in IGI PMID:27038547 BHF-UCL PMID:27038547 RGD:11535100 NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960 		JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137 		JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:73,854,277...73,916,232
Ensembl chr18:73,854,282...73,916,457 		JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,559,599...132,155,092
Ensembl chr 4:131,564,756...132,112,258 		JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801 		JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha involved_in ISO
IEA		 (MGI:4829580|PMID:20516643)
GO_REF:0000107		 RGD
Ensembl		 PMID:20516643 GO_REF:0000107 MGI:4829580 NCBI chr 1:80,815,843...80,825,732
Ensembl chr 1:80,815,850...80,825,802 		JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:62,961,520...62,961,591
Ensembl chr10:62,961,520...62,961,591 		JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:152,111,172...152,226,390
Ensembl chr 1:152,111,188...152,226,383 		JBrowse link
G Pi16 peptidase inhibitor 16 acts_upstream_of_or_within ISO (MGI:3810223|PMID:17909105) RGD PMID:17909105 MGI:3810223 NCBI chr20:7,376,073...7,385,386
Ensembl chr20:7,376,126...7,385,383 		JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346 		JBrowse link
G Rbm10 RNA binding motif protein 10 IMP RGD PMID:30257214 RGD:151667449 NCBI chr  X:1,540,399...1,572,571
Ensembl chr  X:1,540,398...1,572,575 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:43,378,719...43,417,166
Ensembl chr11:43,377,216...43,417,202 		JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747 		JBrowse link
G Zfp418 zinc finger protein 418 acts_upstream_of_or_within ISO (MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:5920524 NCBI chr 1:66,581,406...66,594,247
Ensembl chr 1:66,581,287...66,594,242 		JBrowse link
negative regulation of muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:19260063 RGD:10041027 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nol3 nucleolar protein 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5573029|PMID:24312627)		 Ensembl
RGD		 PMID:24312627 GO_REF:0000107 MGI:5573029 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
negative regulation of muscle hyperplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klf4 KLF transcription factor 4 involved_in IMP PMID:19531492 UniProt PMID:19531492 RGD:8553301 NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3702849|PMID:9466966)		 Ensembl
RGD		 PMID:9466966 GO_REF:0000107 MGI:3702849 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
negative regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Igfbp5 insulin-like growth factor binding protein 5 involved_in ISO (MGI:3039207|PMID:15010534) RGD PMID:15010534 MGI:3039207 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156 		JBrowse link
positive regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:29466442 RGD:329337358 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
G Adk adenosine kinase IMP RGD PMID:21335462 RGD:6482642 NCBI chr15:2,863,241...3,246,453
Ensembl chr15:2,863,244...3,246,510 		JBrowse link
G Adra1a adrenoceptor alpha 1A acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5888970|PMID:27994061)
GO_REF:0000107		 RGD
Ensembl		 PMID:27994061 GO_REF:0000107 MGI:5888970 NCBI chr15:40,830,125...40,935,902
Ensembl chr15:40,832,534...40,927,500 		JBrowse link
G Agt angiotensinogen involved_in IDA PMID:8348686 BHF-UCL PMID:8348686 RGD:8553767 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Becn1 beclin 1 acts_upstream_of_or_within ISO MGI:2683833 (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA
IMP		 (PMID:17921333)
GO_REF:0000107		 RGD
Ensembl		 PMID:17921333 PMID:17921333 GO_REF:0000107, RGD:2302083 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
G Camk2d calcium/calmodulin-dependent protein kinase II delta involved_in ISO
ISS		 (PMID:17179159)
GO_REF:0000024		 RGD
UniProt		 PMID:17179159 GO_REF:0000024 NCBI chr 2:215,023,785...215,287,351
Ensembl chr 2:215,024,004...215,286,178 		JBrowse link
G Cdk9 cyclin-dependent kinase 9 IMP RGD PMID:20081228 RGD:9698419 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410 		JBrowse link
G Ece1 endothelin converting enzyme 1 IMP RGD PMID:20099522 RGD:7243873 NCBI chr 5:150,077,679...150,179,375
Ensembl chr 5:150,077,644...150,179,371 		JBrowse link
G Edn1 endothelin 1 involved_in ISO (PMID:12847114) RGD PMID:12847114 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Gsn gelsolin IMP RGD PMID:24505034 RGD:329333013 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Hand2 heart and neural crest derivatives expressed 2 involved_in ISO
IEA		 UniProtKB:P63328|UniProtKB:Q02078 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr16:32,917,448...32,920,791
Ensembl chr16:32,917,823...32,919,891 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO (PMID:19654000), (PMID:19933931) RGD PMID:19654000 PMID:19933931 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Mef2a myocyte enhancer factor 2a involved_in ISO
IEA		 UniProtKB:P61296 (PMID:24161931)
GO_REF:0000107		 RGD
Ensembl		 PMID:24161931 GO_REF:0000107 NCBI chr 1:120,847,874...120,982,488
Ensembl chr 1:120,850,080...120,981,948 		JBrowse link
G Mef2c myocyte enhancer factor 2C involved_in IMP PMID:19654000 UniProt PMID:19654000 RGD:5131609 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
G Mtpn myotrophin involved_in ISO
IMP		 (PMID:10329199)
PMID:18693253		 RGD PMID:10329199 PMID:18693253 RGD:8553542 NCBI chr 4:64,159,273...64,186,686
Ensembl chr 4:64,157,641...64,186,724 		JBrowse link
G Nr4a3 nuclear receptor subfamily 4, group A, member 3 involved_in IMP PMID:25625556 UniProt PMID:25625556 RGD:10054073 NCBI chr 5:62,361,588...62,401,489
Ensembl chr 5:62,361,822...62,402,733 		JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 involved_in IMP PMID:25625556 UniProt PMID:25625556 RGD:10054073 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404 		JBrowse link
G Pde5a phosphodiesterase 5A involved_in ISO
IEA		 (MGI:3836877|PMID:19127022)
GO_REF:0000107		 RGD
Ensembl		 PMID:19127022 GO_REF:0000107 MGI:3836877 NCBI chr 2:210,858,515...211,003,480
Ensembl chr 2:210,858,063...210,999,701 		JBrowse link
G Pde9a phosphodiesterase 9A involved_in ISS
ISO		 GO_REF:0000024
(MGI:5634842|PMID:25799991)		 UniProt
RGD		 PMID:25799991 GO_REF:0000024 MGI:5634842 NCBI chr20:9,469,809...9,562,949
Ensembl chr20:9,469,848...9,562,948 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO RNAcentral:URS0000021B51_10090|UniProtKB:P61296 (MGI:5562625|PMID:24161931), (MGI:5784969|PMID:24657879) RGD PMID:24161931 PMID:24657879 MGI:5562625 MGI:5784969 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Prkca protein kinase C, alpha involved_in IDA PMID:11864993 UniProt PMID:11864993 RGD:8554603 NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012 		JBrowse link
G Ptk2 protein tyrosine kinase 2 acts_upstream_of_or_within ISO (MGI:5888970|PMID:27994061) RGD PMID:27994061 MGI:5888970 NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:28679962)		 Ensembl
RGD		 PMID:28679962 GO_REF:0000107 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in IMP
ISO		 PMID:28679962
(MGI:6158813|PMID:28679962)		 RGD PMID:28679962 PMID:28679962 MGI:6158813, RGD:13601991 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Slc9a1 solute carrier family 9 member A1 involved_in ISO (PMID:21359875) RGD PMID:21359875 NCBI chr 5:145,576,341...145,629,630
Ensembl chr 5:145,576,334...145,629,624 		JBrowse link
G Twf1 twinfilin actin-binding protein 1 involved_in ISO (MGI:5882879|PMID:20571053) RGD PMID:20571053 MGI:5882879 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894 		JBrowse link
positive regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ppp3ca protein phosphatase 3 catalytic subunit alpha involved_in ISO (MGI:3848765|PMID:19287093) RGD PMID:19287093 MGI:3848765 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Trpc3 transient receptor potential cation channel, subfamily C, member 3 involved_in ISO (PMID:19287093) RGD PMID:19287093 NCBI chr 2:119,481,313...119,619,333
Ensembl chr 2:119,481,400...119,558,855 		JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:255,771,962...255,774,973
Ensembl chr 1:255,771,597...255,807,259 		JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA		 RGD PMID:21550986 PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:70,184,101...70,624,369
Ensembl chr 6:70,184,175...70,619,738 		JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:98,645,238...98,677,253
Ensembl chr 7:98,645,182...98,677,248 		JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:3,547,702...3,585,064
Ensembl chr20:3,572,056...3,584,996 		JBrowse link
G Edn1 endothelin 1 involved_in ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776 		JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891 		JBrowse link
G Igf1 insulin-like growth factor 1 involved_in ISO
IEA		 RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107		 RGD
Ensembl		 PMID:24117217 GO_REF:0000107 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296 		JBrowse link
G Mir19a microRNA 19a involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr15:92,180,912...92,180,993
Ensembl chr15:92,180,912...92,180,993 		JBrowse link
G Mir19b1 microRNA 19b-1 involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr15:92,181,214...92,181,300
Ensembl chr15:92,181,214...92,181,300 		JBrowse link
G Mir19b2 microRNA 19b-2 involved_in ISO UniProtKB:P05019 (PMID:24117217) RGD PMID:24117217 NCBI chr  X:132,422,072...132,422,167
Ensembl chr  X:132,422,072...132,422,167 		JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349 PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:24,034,069...24,044,340
Ensembl chr15:24,034,106...24,044,338 		JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:19,189,408...19,200,785
Ensembl chr 8:19,189,373...19,200,785 		JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260 		JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:46,072,935...46,076,730
Ensembl chr16:46,072,939...46,076,733 		JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:2,133,085...2,147,795
Ensembl chr 9:2,133,671...2,147,799 		JBrowse link
positive regulation of muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ep300 E1A binding protein p300 IMP RGD PMID:22292478 RGD:7349318 NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088 		JBrowse link
G Foxo3 forkhead box O3 involved_in ISO (MGI:3771642|PMID:18054316), (MGI:3771681|PMID:18054315) RGD PMID:18054315 PMID:18054316 MGI:3771642 MGI:3771681 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561 		JBrowse link
G Myog myogenin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5508727|PMID:21465538)		 UniProt
Ensembl
RGD		 PMID:21465538 GO_REF:0000024 GO_REF:0000107 MGI:5508727 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
positive regulation of muscle hyperplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aif1 allograft inflammatory factor 1 IMP RGD PMID:18779232 RGD:2313013 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
positive regulation of skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:23470307 RGD:10041029 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Mymk myomaker, myoblast fusion factor involved_in ISO (MGI:6116777|PMID:28186492) RGD PMID:28186492 MGI:6116777 NCBI chr 3:10,388,363...10,397,294
Ensembl chr 3:10,388,361...10,397,343 		JBrowse link
regulation of cardiac muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lmcd1 LIM and cysteine-rich domains 1 involved_in ISO (PMID:20026769)
(MGI:4442539|PMID:20026769)		 RGD PMID:20026769 MGI:4442539 NCBI chr 4:145,393,153...145,452,049
Ensembl chr 4:145,393,145...145,452,046 		JBrowse link
regulation of cardiac muscle hypertrophy in response to stress term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acacb acetyl-CoA carboxylase beta IMP RGD PMID:31709908 RGD:329901803 NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655 		JBrowse link
G Bmp10 bone morphogenetic protein 10 involved_in ISO
IEA		 (PMID:17921333)
GO_REF:0000107		 RGD
Ensembl		 PMID:17921333 GO_REF:0000107 NCBI chr 4:119,872,066...119,877,694
Ensembl chr 4:119,872,045...119,878,627 		JBrowse link
regulation of skeletal muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cmya5 cardiomyopathy associated 5 acts_upstream_of_or_within ISO MGI:107164 (MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:5056263 NCBI chr 2:24,279,520...24,378,253
Ensembl chr 2:24,279,528...24,378,364 		JBrowse link
response to denervation involved in regulation of muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5554485|PMID:24234654) RGD PMID:24234654 MGI:5554485 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Casq1 calsequestrin 1 IEP RGD PMID:15138610 RGD:2313228 NCBI chr13:84,670,648...84,680,339
Ensembl chr13:84,670,649...84,680,339 		JBrowse link
G Dag1 dystroglycan 1 IEP RGD PMID:8906620 RGD:11552584 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Dmd dystrophin IEP RGD PMID:8906620 RGD:11552584 NCBI chr  X:47,272,324...49,504,219
Ensembl chr  X:47,272,331...49,504,207 		JBrowse link
G Fbxo32 F-box protein 32 involved_in IEA
ISO
ISS		 GO_REF:0000107
(MGI:5508727|PMID:21465538)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:21465538 GO_REF:0000024 GO_REF:0000107 MGI:5508727 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Hdac4 histone deacetylase 4 involved_in ISO
IEA		 (MGI:4365327|PMID:19109424)
GO_REF:0000107		 RGD
Ensembl		 PMID:19109424 GO_REF:0000107 MGI:4365327 NCBI chr 9:92,503,467...92,750,164
Ensembl chr 9:92,507,611...92,750,164 		JBrowse link
G Mtmr4 myotubularin related protein 4 IEP RGD PMID:19125695 RGD:7242174 NCBI chr10:72,393,411...72,416,342
Ensembl chr10:72,392,551...72,416,342 		JBrowse link
G Myog myogenin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5508727|PMID:21465538)		 UniProt
Ensembl
RGD		 PMID:21465538 GO_REF:0000024 GO_REF:0000107 MGI:5508727 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Nedd4 NEDD4 E3 ubiquitin protein ligase IEP RGD PMID:19125695 RGD:7242174 NCBI chr 8:73,384,095...73,468,951
Ensembl chr 8:73,383,695...73,468,951 		JBrowse link
G Runx1 RUNX family transcription factor 1 IEP RGD PMID:7969143 RGD:634721 NCBI chr11:31,839,880...32,074,427
Ensembl chr11:31,843,764...32,074,542 		JBrowse link
G Scn5a sodium voltage-gated channel alpha subunit 5 IMP RGD PMID:22336133 RGD:6484222 NCBI chr 8:119,220,905...119,318,816
Ensembl chr 8:119,220,905...119,318,769 		JBrowse link
G Sgca sarcoglycan, alpha IEP RGD PMID:8906620 RGD:11552584 NCBI chr10:79,904,698...79,922,808
Ensembl chr10:79,908,738...79,922,813 		JBrowse link
G Trim63 tripartite motif containing 63 involved_in ISO (MGI:5508727|PMID:21465538) RGD PMID:21465538 MGI:5508727 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322 		JBrowse link
G Utrn utrophin IEP RGD PMID:8906620 RGD:11552584 NCBI chr 1:6,720,854...7,224,313
Ensembl chr 1:6,722,594...7,224,313 		JBrowse link
response to electrical stimulus involved in regulation of muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fbxo32 F-box protein 32 involved_in IDA PMID:21465538 UniProt PMID:21465538 RGD:8553783 NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436 		JBrowse link
G Myog myogenin involved_in IEP
IDA		 PMID:21465538 RGD
UniProt		 PMID:10942718 PMID:21465538 RGD:9686130, RGD:8553783 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:15716393 RGD:1643029 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP RGD PMID:15716393 RGD:1643029 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Trim63 tripartite motif containing 63 involved_in IDA PMID:21465538 UniProt PMID:21465538 RGD:8553783 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322 		JBrowse link
response to injury involved in regulation of muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ndufs4 NADH:ubiquinone oxidoreductase subunit S4 acts_upstream_of_or_within ISO MGI:3793713 (MGI:6280037|PMID:29501746) RGD PMID:29501746 MGI:6280037 NCBI chr 2:45,951,327...46,061,829
Ensembl chr 2:45,951,313...46,061,846 		JBrowse link
G Nol3 nucleolar protein 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3822950|PMID:18782777)		 Ensembl
RGD		 PMID:18782777 GO_REF:0000107 MGI:3822950 NCBI chr19:33,154,061...33,158,250
Ensembl chr19:33,154,062...33,158,250 		JBrowse link
response to muscle activity involved in regulation of muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agt angiotensinogen involved_in IMP PMID:8252633 BHF-UCL PMID:8252633 RGD:8553951 NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977 		JBrowse link
G Myog myogenin involved_in IDA PMID:14751541 UniProt PMID:14751541 RGD:8553747 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Prkag3 protein kinase AMP-activated non-catalytic subunit gamma 3 acts_upstream_of_or_within ISO MGI:3055131 (MGI:3583413|PMID:15857891) RGD PMID:15857891 MGI:3583413 NCBI chr 9:76,295,715...76,304,959
Ensembl chr 9:76,295,715...76,304,959 		JBrowse link
G Selenon selenoprotein N acts_upstream_of_or_within ISO (MGI:5494499|PMID:23325319) RGD PMID:23325319 MGI:5494499 NCBI chr 5:146,748,638...146,764,656
Ensembl chr 5:146,748,652...146,763,059 		JBrowse link
G Srl sarcalumenin acts_upstream_of_or_within ISO MGI:3605474 (MGI:3604272|PMID:15998745) RGD PMID:15998745 MGI:3604272 NCBI chr10:11,033,976...11,078,103
Ensembl chr10:11,034,035...11,078,101 		JBrowse link
skeletal muscle adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cacna1s calcium voltage-gated channel subunit alpha1 S acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:1856326 (MGI:3616422|PMID:2419767)
GO_REF:0000107		 RGD
Ensembl		 PMID:2419767 GO_REF:0000107 MGI:3616422 NCBI chr13:47,493,949...47,564,194
Ensembl chr13:47,493,949...47,564,318 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 IEP RGD PMID:24284598 RGD:329337337 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
skeletal muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:5554485|PMID:24234654) RGD PMID:24234654 MGI:5554485 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Asb2 ankyrin repeat and SOCS box-containing 2 involved_in ISS
ISO		 GO_REF:0000024
(MGI:6716965|PMID:27182554)		 UniProt
RGD		 PMID:27182554 GO_REF:0000024 MGI:6716965 NCBI chr 6:122,474,754...122,511,014
Ensembl chr 6:122,474,756...122,510,854 		JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator involved_in ISO (MGI:5707584|PMID:21364645) RGD PMID:21364645 MGI:5707584 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034 		JBrowse link
G Il15 interleukin 15 IEP RGD PMID:17135303 RGD:1626613 NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820 		JBrowse link
G Ireb2 iron responsive element binding protein 2 IEP RGD PMID:23994517 RGD:12904021 NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611 		JBrowse link
G Mstn myostatin IEP RGD PMID:15758361 RGD:2303594 NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933 		JBrowse link
G Myod1 myogenic differentiation 1 IEP RGD PMID:12839833 RGD:1302305 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Myog myogenin IEP RGD PMID:12839833 RGD:1302305 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
G Ppargc1a PPARG coactivator 1 alpha IEP RGD PMID:16870628 RGD:10053649 NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656 		JBrowse link
G Rps6kb1 ribosomal protein S6 kinase B1 IEP RGD PMID:17885021 RGD:1642984 NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908 		JBrowse link
G Trim63 tripartite motif containing 63 IEP RGD PMID:11679633 RGD:633893 NCBI chr 5:146,533,492...146,547,332
Ensembl chr 5:146,533,507...146,547,322 		JBrowse link
skeletal muscle fiber adaptation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acta1 actin, alpha 1, skeletal muscle IEP RGD PMID:16428321 RGD:1598721 NCBI chr19:51,883,709...51,886,735
Ensembl chr19:51,883,715...51,886,742 		JBrowse link
G Myod1 myogenic differentiation 1 acts_upstream_of_or_within ISO (MGI:3840749|PMID:19319192) RGD PMID:19319192 MGI:3840749 NCBI chr 1:96,884,864...96,887,574
Ensembl chr 1:96,884,948...96,887,554 		JBrowse link
G Myoz1 myozenin 1 acts_upstream_of_or_within_positive_effect ISO (MGI:3831256|PMID:18846255) RGD PMID:18846255 MGI:3831256 NCBI chr15:3,644,333...3,651,584
Ensembl chr15:3,644,368...3,652,884 		JBrowse link
G Myoz2 myozenin 2 involved_in ISO (MGI:3513659|PMID:15543153) RGD PMID:15543153 MGI:3513659 NCBI chr 2:211,141,463...211,168,187
Ensembl chr 2:211,141,463...211,168,221 		JBrowse link
skeletal muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor IMP RGD PMID:7957162 RGD:10043318 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Myoc myocilin involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5320812|PMID:22371502)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:22371502 GO_REF:0000024 GO_REF:0000107 MGI:5320812 NCBI chr13:74,976,730...74,987,128
Ensembl chr13:74,976,730...74,987,127 		JBrowse link
smooth muscle hyperplasia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3702849|PMID:9466966)		 Ensembl
RGD		 PMID:9466966 GO_REF:0000107 MGI:3702849 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
smooth muscle hypertrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyba cytochrome b-245 alpha chain involved_in IMP PMID:8798532 BHF-UCL PMID:8798532 RGD:2317869 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721 		JBrowse link
striated muscle atrophy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin involved_in ISO
IEA		 (PMID:19549824)
GO_REF:0000107		 RGD
Ensembl		 PMID:19549824 GO_REF:0000107 NCBI chr 3:18,585,166...18,638,404
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Myog myogenin involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(MGI:5508727|PMID:21465538)		 UniProt
Ensembl
RGD		 PMID:21465538 GO_REF:0000024 GO_REF:0000107 MGI:5508727 NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039 		JBrowse link
transition between fast and slow fiber term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Actn3 actinin alpha 3 involved_in ISO (MGI:3759354|PMID:17828264) RGD PMID:17828264 MGI:3759354 NCBI chr 1:202,159,081...202,175,012
Ensembl chr 1:202,159,082...202,175,012 		JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:3829334|PMID:18978355)
GO_REF:0000107		 RGD
Ensembl		 PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101 		JBrowse link
G Gtf2ird2 GTF2I repeat domain containing 2 acts_upstream_of_or_within ISO (MGI:5504578|PMID:22899722) RGD PMID:22899722 MGI:5504578 NCBI chr12:22,497,767...22,536,455
Ensembl chr12:22,498,091...22,536,263 		JBrowse link
G Myh7 myosin heavy chain 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3829334|PMID:18978355)		 Ensembl
RGD		 PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chr15:28,446,550...28,469,888
Ensembl chr15:28,446,550...28,468,217 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO (MGI:3829530|PMID:18408153) RGD PMID:18408153 MGI:3829530 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha acts_upstream_of_or_within ISO (MGI:5056263|PMID:21427212) RGD PMID:21427212 MGI:5056263 NCBI chr 2:225,165,981...225,440,978
Ensembl chr 2:225,165,766...225,438,974 		JBrowse link
G Tead1 TEA domain transcription factor 1 acts_upstream_of_or_within ISO (MGI:3829334|PMID:18978355) RGD PMID:18978355 MGI:3829334 NCBI chr 1:166,791,900...167,010,591
Ensembl chr 1:166,792,628...167,003,369 		JBrowse link
G Tnnc1 troponin C1, slow skeletal and cardiac type acts_upstream_of_or_within ISO (MGI:3829334|PMID:18978355) RGD PMID:18978355 MGI:3829334 NCBI chr16:6,400,801...6,405,634
Ensembl chr16:6,402,171...6,405,634 		JBrowse link
G Tnni1 troponin I1, slow skeletal type involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3829334|PMID:18978355)		 Ensembl
RGD		 PMID:18978355 GO_REF:0000107 MGI:3829334 NCBI chr13:47,229,217...47,241,640
Ensembl chr13:47,229,216...47,241,644 		JBrowse link
G Tnnt1 troponin T1, slow skeletal type acts_upstream_of_or_within ISO (MGI:3829334|PMID:18978355) RGD PMID:18978355 MGI:3829334 NCBI chr 1:69,306,362...69,316,721
Ensembl chr 1:69,306,362...69,316,721 		JBrowse link
transition between slow and fast fiber term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gtf2i general transcription factor II I acts_upstream_of_or_within ISO (MGI:5504578|PMID:22899722) RGD PMID:22899722 MGI:5504578 NCBI chr12:22,400,933...22,476,243
Ensembl chr12:22,401,431...22,476,243 		JBrowse link
G Gtf2ird1 GTF2I repeat domain containing 1 acts_upstream_of_or_within ISO (MGI:5504578|PMID:22899722) RGD PMID:22899722 MGI:5504578 NCBI chr12:22,254,113...22,361,052
Ensembl chr12:22,254,221...22,361,040 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    response to stimulus 10408
      muscle adaptation 155
        muscle atrophy + 21
        muscle hyperplasia + 3
        muscle hypertrophy in response to stress + 32
        negative regulation of muscle adaptation + 13
        positive regulation of muscle adaptation + 8
        regulation of muscle adaptation + 122
        smooth muscle adaptation + 2
        striated muscle adaptation + 63
Path 2
Term Annotations click to browse term
  biological_process 19574
    multicellular organismal process 9171
      system process 3469
        muscle system process 483
          muscle adaptation 155
            muscle atrophy + 21
            muscle hyperplasia + 3
            muscle hypertrophy in response to stress + 32
            negative regulation of muscle adaptation + 13
            positive regulation of muscle adaptation + 8
            regulation of muscle adaptation + 122
            smooth muscle adaptation + 2
            striated muscle adaptation + 63
paths to the root