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ONTOLOGY REPORT - ANNOTATIONS

Term:negative regulation of DNA-binding transcription factor activity
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Accession:GO:0043433 term browser browse the term
Definition:Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
Synonyms:exact_synonym: down regulation of transcription factor activity;   downregulation of transcription factor activity;   negative regulation of sequence-specific DNA binding transcription factor activity
 narrow_synonym: inhibition of transcription factor activity;   negative regulation of androgen receptor activity;   negative regulation of thyroid hormone receptor activity
 broad_synonym: negative regulation of transcription factor activity
 alt_id: GO:1904168;   GO:2000824


show annotations for term's descendants           Sort by:
negative regulation of DNA-binding transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO RGD PMID:20308610 RGD:6483365 NCBI chr14:59,113,527...59,168,421
Ensembl chr14:59,113,844...59,168,395 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626
G HNF4A hepatocyte nuclear factor 4 alpha ISO STAT5b RGD PMID:16584384 RGD:1625011 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,500 		JBrowse link
G HR HR lysine demethylase and nuclear receptor corepressor ISO RGD PMID:11641275 RGD:1599577 NCBI chr14:6,386,900...6,404,968
Ensembl chr14:6,386,903...6,407,031 		JBrowse link
G NR0B1 nuclear receptor subfamily 0 group B member 1 ISO RGD PMID:12697699 RGD:1624302 NCBI chr  X:26,117,874...26,122,951
Ensembl chr  X:26,117,874...26,122,951 		JBrowse link
G RPL11 ribosomal protein L11 ISO RGD PMID:16280383 RGD:11035228 NCBI chr 6:81,523,510...81,526,925
Ensembl chr 6:81,522,742...81,530,436 		JBrowse link
G THRA thyroid hormone receptor alpha ISO RGD PMID:2537467 RGD:1580107 NCBI chr12:22,270,506...22,296,684
Ensembl chr12:22,270,062...22,296,618 		JBrowse link
cytoplasmic sequestering of NF-kappaB term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NFKBIA NFKB inhibitor alpha ISO RGD PMID:9343439 PMID:9918814 PMID:10620707 PMID:16580131 RGD:2298880 RGD:2298882 RGD:2298908 RGD:2298917 NCBI chr 7:64,508,119...64,510,754
Ensembl chr 7:64,507,822...64,511,277 		JBrowse link
G NFKBIB NFKB inhibitor beta ISO RGD PMID:9343439 PMID:16580131 RGD:2298908 RGD:2298917 NCBI chr 6:47,703,644...47,712,661
Ensembl chr 6:47,703,647...47,712,654 		JBrowse link
cytoplasmic sequestering of transcription factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KEAP1 kelch like ECH associated protein 1 ISO RGD PMID:11439354 RGD:727319 NCBI chr 2:69,280,940...69,290,267
Ensembl chr 2:69,276,336...69,294,382 		JBrowse link
negative regulation of CREB transcription factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DDIT3 DNA damage inducible transcript 3 ISO RGD PMID:15829559 RGD:1599733 NCBI chr 5:22,785,441...22,789,867
Ensembl chr 5:22,785,445...22,789,829 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17799
    biological regulation 12896
      regulation of molecular function 303
        negative regulation of molecular function 120
          negative regulation of DNA-binding transcription factor activity 11
            cytoplasmic sequestering of transcription factor + 3
            negative regulation of CREB transcription factor activity 1
            negative regulation of NF-kappaB transcription factor activity + 2
Path 2
Term Annotations click to browse term
  biological_process 17799
    metabolic process 10358
      organic substance metabolic process 9930
        organic cyclic compound metabolic process 5601
          nucleobase-containing compound metabolic process 5148
            nucleic acid metabolic process 4652
              RNA metabolic process 4101
                RNA biosynthetic process 3144
                  DNA-templated transcription 3120
                    regulation of DNA-templated transcription 2996
                      regulation of DNA-binding transcription factor activity 29
                        negative regulation of DNA-binding transcription factor activity 11
                          cytoplasmic sequestering of transcription factor + 3
                          negative regulation of CREB transcription factor activity 1
                          negative regulation of NF-kappaB transcription factor activity + 2
paths to the root