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ONTOLOGY REPORT - ANNOTATIONS


Term:memory T cell differentiation
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Accession:GO:0043379 term browser browse the term
Definition:The process in which a newly activated T cell acquires specialized features of a memory T cell.
Comment:Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.
Synonyms:exact_synonym: memory T lymphocyte differentiation
 related_synonym: memory T cell development



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memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tsc1 TSC complex subunit 1 acts_upstream_of_or_within ISO MGI:2656240 (MGI:5608813|PMID:25271321) RGD PMID:25271321 MGI:5608813 NCBI chr 3:11,969,547...12,018,591
Ensembl chr 3:11,979,729...12,015,674
JBrowse link
negative regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgl2 fibrinogen-like 2 acts_upstream_of_or_within ISO MGI:3582343 (MGI:6188369|PMID:29341118) RGD PMID:29341118 MGI:6188369 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Ifnl1 interferon, lambda 1 involved_in ISO (PMID:19346497) RGD PMID:19346497 NCBI chr 1:83,798,651...83,800,297
Ensembl chr 1:83,798,703...83,800,235
JBrowse link
positive regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd46 CD46 molecule involved_in ISO (PMID:12540904) RGD PMID:12540904 NCBI chr13:106,575,586...106,606,325
Ensembl chr13:106,574,858...106,660,445
JBrowse link
G Il23a interleukin 23 subunit alpha involved_in ISO (MGI:3027369|PMID:14688363) RGD PMID:14688363 MGI:3027369 NCBI chr 7:721,809...723,923
Ensembl chr 7:721,809...723,923
JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 involved_in ISS
ISO
GO_REF:0000024
(MGI:6119963|PMID:29230018)
UniProt
RGD
PMID:29230018 GO_REF:0000024 MGI:6119963 NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
JBrowse link
G RT1-Da RT1 class II, locus Da involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,513,464...4,518,457
Ensembl chr20:4,512,911...4,518,455
JBrowse link
G RT1-Db1 RT1 class II, locus Db1 involved_in ISO (PMID:27591323) RGD PMID:27591323 NCBI chr20:4,548,664...4,558,237
Ensembl chr20:4,548,666...4,558,258
JBrowse link
G Tnfsf4 TNF superfamily member 4 involved_in ISO (MGI:3806904|PMID:18713990) RGD PMID:18713990 MGI:3806904 NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788
JBrowse link
regulation of memory T cell differentiation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl6 BCL6, transcription repressor acts_upstream_of_or_within ISO MGI:2158436 (MGI:3051162|PMID:15240675) RGD PMID:15240675 MGI:3051162 NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18734
    immune system process 2730
      immunological memory process 14
        immunological memory formation process 11
          memory T cell differentiation 10
            negative regulation of memory T cell differentiation 2
            positive regulation of memory T cell differentiation 6
            regulation of memory T cell differentiation + 9
Path 2
Term Annotations click to browse term
  biological_process 18734
    developmental process 6893
      anatomical structure development 6368
        multicellular organism development 5437
          system development 4939
            immune system development 1129
              hematopoietic or lymphoid organ development 1061
                hemopoiesis 1012
                  leukocyte differentiation 634
                    mononuclear cell differentiation 485
                      lymphocyte differentiation 426
                        T cell differentiation 306
                          T cell differentiation involved in immune response 79
                            memory T cell differentiation 10
                              negative regulation of memory T cell differentiation 2
                              positive regulation of memory T cell differentiation 6
                              regulation of memory T cell differentiation + 9
paths to the root