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ONTOLOGY REPORT - ANNOTATIONS

Term:response to dsRNA
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Accession:GO:0043331 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.
Synonyms:exact_synonym: response to double-stranded RNA


show annotations for term's descendants           Sort by:
response to dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Peli1 pellino E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO MGI:4361448 (MGI:4359971|PMID:19734906) RGD PMID:19734906 MGI:4359971 NCBI chr14:95,254,274...95,309,168
Ensembl chr14:95,254,589...95,308,285 		JBrowse link
G Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 involved_in ISO (PMID:15705586) RGD PMID:15705586 NCBI chr18:59,986,187...59,990,174
Ensembl chr18:59,986,017...59,992,429 		JBrowse link
G Tlr3 toll-like receptor 3 IDA poly(I:C) - a synthetic analog of double-stranded RNA, a molecular pattern associated with viral infection RGD PMID:16973131 RGD:1643119 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
cellular response to dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IEP miR-132 RGD PMID:19958814 RGD:2325933 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Grin2a glutamate ionotropic receptor NMDA type subunit 2A IEP miR-132 RGD PMID:19958814 RGD:2325933 NCBI chr10:5,630,684...6,043,341
Ensembl chr10:5,631,369...6,044,637 		JBrowse link
G Grin2b glutamate ionotropic receptor NMDA type subunit 2B IEP miR-132 RGD PMID:19958814 RGD:2325933 NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279 		JBrowse link
G Ifnb1 interferon beta 1 acts_upstream_of_or_within
involved_in		 ISO (PMID:18596219)
(MGI:3814787|PMID:18596219)		 RGD PMID:18596219 MGI:3814787 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 acts_upstream_of_or_within ISO MGI:1857225 (MGI:5604160|PMID:24114535) RGD PMID:24114535 MGI:5604160 NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G P2rx7 purinergic receptor P2X 7 acts_upstream_of_or_within ISO MGI:2386080 (MGI:5604160|PMID:24114535) RGD PMID:24114535 MGI:5604160 NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619 		JBrowse link
G Pde12 phosphodiesterase 12 involved_in IEA
ISO		 GO_REF:0000107
(PMID:15231837)		 Ensembl
RGD		 PMID:15231837 GO_REF:0000107 NCBI chr16:1,915,386...1,925,427
Ensembl chr16:1,915,386...1,925,887 		JBrowse link
G Riok3 RIO kinase 3 involved_in ISO (PMID:24807708) RGD PMID:24807708 NCBI chr18:3,327,776...3,353,350
Ensembl chr18:3,327,776...3,353,343 		JBrowse link
cellular response to exogenous dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705 		JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IBA		 (MGI:5487472|PMID:23258413), (MGI:5897489|PMID:28363908), (MGI:5897502|PMID:28214358), (MGI:5908326|PMID:24077100)
PMID:21873635		 RGD PMID:23258413 PMID:24077100 PMID:28214358 PMID:28363908 PMID:21873635 MGI:5487472 MGI:5897489 MGI:5897502 MGI:5908326, RGD:13792537 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496 		JBrowse link
G Ciita class II, major histocompatibility complex, transactivator IEP RGD PMID:10051633 RGD:7242894 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440 		JBrowse link
G Colec12 collectin sub-family member 12 involved_in
NOT|involved_in		 ISO (PMID:25204797) RGD PMID:25204797 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618 		JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069 		JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978 		JBrowse link
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456 		JBrowse link
G Irf1 interferon regulatory factor 1 IEP RGD PMID:11694343 RGD:5128789 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166 		JBrowse link
G Irf3 interferon regulatory factor 3 IEP RGD PMID:18223009 RGD:5128810 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO		 GO_REF:0000024
(PMID:16127453), (PMID:21957149)		 UniProt
RGD		 PMID:16127453 PMID:21957149 GO_REF:0000024 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094 		JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863 		JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:26046437)		 UniProt
RGD		 PMID:26046437 GO_REF:0000024 NCBI chr  X:14,603,516...14,608,091
Ensembl chr  X:14,603,539...14,608,087 		JBrowse link
G Ralb RAS like proto-oncogene B involved_in ISO
IEA		 (PMID:24056301)
GO_REF:0000107		 RGD
Ensembl		 PMID:24056301 GO_REF:0000107 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202 		JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO (PMID:18818105) RGD PMID:18818105 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335 		JBrowse link
G Tlr3 toll-like receptor 3 IEP
IMP		 RGD PMID:20937230 PMID:15920723 RGD:5128701, RGD:2301737 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 acts_upstream_of_or_within ISO (MGI:4868308|PMID:21102435) RGD PMID:21102435 MGI:4868308 NCBI chr 4:67,012,151...67,062,406
Ensembl chr 4:67,012,185...67,062,428 		JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IBA		 (PMID:30193849)
(MGI:6271678|PMID:30193849)
PMID:21873635		 RGD PMID:30193849 PMID:21873635 MGI:6271678, RGD:13792537 NCBI chr 3:140,872,460...140,875,851
Ensembl chr 3:140,872,460...140,882,408 		JBrowse link
regulation of eIF2 alpha phosphorylation by dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Npm1 nucleophosmin 1 involved_in ISO
ISS		 (PMID:12882984)
GO_REF:0000024		 RGD
UniProt		 PMID:12882984 GO_REF:0000024 NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645 		JBrowse link
response to exogenous dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (MGI:3697751|PMID:17187069) RGD PMID:17187069 MGI:3697751 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237 		JBrowse link
G Ddx1 DEAD-box helicase 1 acts_upstream_of_or_within ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365 		JBrowse link
G Ddx21 DExD-box helicase 21 acts_upstream_of_or_within ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543 		JBrowse link
G Dhx36 DEAH-box helicase 36 acts_upstream_of_or_within ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572 		JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 IEP RGD PMID:15920723 RGD:2301737 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971 		JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,069,483...103,070,052
Ensembl chr 5:103,069,483...103,070,052 		JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,187,852...103,188,430 JBrowse link
G Ifnb1 interferon beta 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 PMID:21873635
(PMID:21266579)		 RGD PMID:21266579 PMID:21873635 RGD:13792537 NCBI chr 5:103,020,969...103,021,523
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Ifne interferon, epsilon involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,538,001...103,627,561
Ensembl chr 5:103,569,675...103,572,256 		JBrowse link
G Ifnk interferon kappa involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281 		JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927) RGD PMID:12150927 MGI:2183694 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121 		JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (MGI:2669022|PMID:12855817), (MGI:2670551|PMID:12872135) RGD PMID:12855817 PMID:12872135 MGI:2669022 MGI:2670551 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935 		JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO MGI:3720053 (MGI:3761841|PMID:18026101) RGD PMID:18026101 MGI:3761841 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603 		JBrowse link
G LOC100911527 interferon alpha-12-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,524,733...103,525,302
Ensembl chr 5:103,524,733...103,525,302 		JBrowse link
G LOC120103163 interferon alpha-12-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,494,442...103,495,077
Ensembl chr 5:103,494,448...103,495,002 		JBrowse link
G LOC120103164 interferon alpha-12-like involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,509,610...103,510,260
Ensembl chr 5:103,509,616...103,510,170 		JBrowse link
G Mapk1 mitogen activated protein kinase 1 acts_upstream_of_or_within ISO (MGI:2670551|PMID:12872135) RGD PMID:12872135 MGI:2670551 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616 		JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO (MGI:2670551|PMID:12872135) RGD PMID:12872135 MGI:2670551 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863 		JBrowse link
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (MGI:2670551|PMID:12872135) RGD PMID:12872135 MGI:2670551 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (MGI:3528786|PMID:15692051) RGD PMID:15692051 MGI:3528786 NCBI chr19:18,379,720...18,422,817
Ensembl chr19:18,382,439...18,417,177 		JBrowse link
G Plin3 perilipin 3 involved_in IEA GO_REF:0000104 UniProt GO_REF:0000104 NCBI chr 9:1,111,178...1,123,117
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Rftn1 raftlin lipid raft linker 1 acts_upstream_of_or_within ISO (PMID:21266579) RGD PMID:21266579 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084 		JBrowse link
G Rftn2 raftlin family member 2 acts_upstream_of_or_within ISO (MGI:4947923|PMID:21266579) RGD PMID:21266579 MGI:4947923 NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810 		JBrowse link
G RGD1560539 similar to interferon alpha 8/6 precursor; IFNa8/6 (B6) involved_in IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 5:103,476,362...103,477,211
Ensembl chr 5:103,476,657...103,477,211 		JBrowse link
G Rig1 RNA sensor RIG-1 acts_upstream_of_or_within ISO (MGI:5050760|PMID:21703541) RGD PMID:21703541 MGI:5050760 NCBI chr 5:55,321,229...55,369,947
Ensembl chr 5:55,321,235...55,370,819 		JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (MGI:2176422|PMID:11894098) RGD PMID:11894098 MGI:2176422 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657 		JBrowse link
G Slc3a2 solute carrier family 3 member 2 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:21266579)
GO_REF:0000107		 RGD
Ensembl		 PMID:21266579 GO_REF:0000107 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931 		JBrowse link
G Stat1 signal transducer and activator of transcription 1 acts_upstream_of_or_within ISO (MGI:2670551|PMID:12872135) RGD PMID:12872135 MGI:2670551 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540 		JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:2679794|MGI:3029019 (MGI:2669022|PMID:12855817), (MGI:2670551|PMID:12872135), (MGI:5050760|PMID:21703541)
GO_REF:0000104
(PMID:21266579)		 RGD
UniProt		 PMID:12855817 PMID:12872135 PMID:21266579 PMID:21703541 GO_REF:0000104 MGI:2669022 MGI:2670551 MGI:5050760 NCBI chr 9:1,102,559...1,115,573
Ensembl chr 9:1,102,366...1,123,147 		JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO MGI:3690535 (MGI:2669022|PMID:12855817)
(PMID:21266579)		 RGD PMID:12855817 PMID:21266579 MGI:2669022 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19903
    response to stimulus 10569
      response to chemical 6107
        response to nitrogen compound 1644
          response to dsRNA 55
            cellular response to dsRNA + 27
            response to exogenous dsRNA + 45
Path 2
Term Annotations click to browse term
  biological_process 19903
    response to stimulus 10569
      response to chemical 6107
        response to organic substance 3783
          response to organic cyclic compound 1514
            response to dsRNA 55
              cellular response to dsRNA + 27
              response to exogenous dsRNA + 45
paths to the root