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ONTOLOGY REPORT - ANNOTATIONS


Term:response to exogenous dsRNA
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Accession:GO:0043330 term browser browse the term
Definition:Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
Comment:Note that the presence of exogenous double-stranded RNA is usually indicative of a viral infection. Consider also annotating to 'response to virus ; GO:0009615'.
Synonyms:exact_synonym: response to exogenous double-stranded RNA
 narrow_synonym: response to viral dsRNA



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response to exogenous dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Card9 caspase recruitment domain family, member 9 acts_upstream_of_or_within ISO MGI:3698412 (PMID:17187069) RGD PMID:17187069 NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
JBrowse link
G Ddx1 DEAD-box helicase 1 acts_upstream_of_or_within ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 6:35,996,469...36,027,340
Ensembl chr 6:35,996,469...36,027,365
JBrowse link
G Ddx21 DExD-box helicase 21 acts_upstream_of_or_within ISO (PMID:21703541) RGD PMID:21703541 NCBI chr20:30,534,319...30,554,513
Ensembl chr20:30,534,319...30,554,543
JBrowse link
G Dhx36 DEAH-box helicase 36 acts_upstream_of_or_within ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 2:146,856,469...146,894,577
Ensembl chr 2:146,856,469...146,894,572
JBrowse link
G Eif2ak2 eukaryotic translation initiation factor 2-alpha kinase 2 IEP RGD PMID:15920723 RGD:2301737 NCBI chr 6:16,189,000...16,224,972
Ensembl chr 6:16,188,979...16,224,971
JBrowse link
G Ifna12l interferon alpha 12 like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,476,362...103,477,427
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211
Ensembl chr 5:103,476,657...103,477,211
JBrowse link
G Ifna4 interferon, alpha 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,069,174...103,070,120
Ensembl chr 5:103,069,483...103,070,052
JBrowse link
G Ifna5 interferon, alpha 5 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,187,852...103,188,430 JBrowse link
G Ifnb1 interferon beta 1 acts_upstream_of_or_within
involved_in
ISO
IBA
(PMID:21266579)
GO_REF:0000033
RGD
GO_Central
PMID:21266579 GO_REF:0000033 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Ifne interferon, epsilon involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,571,630...103,572,290
Ensembl chr 5:103,569,675...103,572,256
JBrowse link
G Ifnk interferon kappa involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:49,732,073...49,734,281
Ensembl chr 5:49,732,073...49,734,281
JBrowse link
G Irak3 interleukin-1 receptor-associated kinase 3 involved_in ISO (MGI:2183694|PMID:12150927)
(PMID:12150927)
RGD PMID:12150927 MGI:2183694 NCBI chr 7:55,653,949...55,714,371
Ensembl chr 7:55,653,962...55,713,121
JBrowse link
G Irf3 interferon regulatory factor 3 acts_upstream_of_or_within ISO (PMID:12855817), (PMID:12872135) RGD PMID:12855817 PMID:12872135 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Kcnj8 potassium inwardly-rectifying channel, subfamily J, member 8 acts_upstream_of_or_within ISO MGI:3720053 (PMID:18026101) RGD PMID:18026101 NCBI chr 4:175,508,908...175,515,829
Ensembl chr 4:175,508,912...175,515,603
JBrowse link
G LOC120103163 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,494,442...103,495,077
Ensembl chr 5:103,494,448...103,495,002
JBrowse link
G LOC120103164 interferon alpha-12-like involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:103,509,610...103,510,260
Ensembl chr 5:103,509,616...103,510,170
JBrowse link
G Mapk1 mitogen activated protein kinase 1 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
(PMID:12872135)
Ensembl
RGD
PMID:12872135 GO_REF:0000107 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 acts_upstream_of_or_within ISO (PMID:12872135) RGD PMID:12872135 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Nfkbia NFKB inhibitor alpha acts_upstream_of_or_within ISO (PMID:12872135) RGD PMID:12872135 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
JBrowse link
G Nod2 nucleotide-binding oligomerization domain containing 2 acts_upstream_of_or_within ISO MGI:3529594 (PMID:15692051) RGD PMID:15692051 NCBI chr19:18,382,369...18,422,817
Ensembl chr19:18,382,439...18,417,177
JBrowse link
G Rftn1 raftlin lipid raft linker 1 acts_upstream_of_or_within ISO (PMID:21266579) RGD PMID:21266579 NCBI chr 9:10,804,611...11,002,084
Ensembl chr 9:10,804,611...11,002,084
JBrowse link
G Rftn2 raftlin family member 2 acts_upstream_of_or_within ISO (PMID:21266579) RGD PMID:21266579 NCBI chr 9:56,651,617...56,707,830
Ensembl chr 9:56,630,460...56,707,810
JBrowse link
G Rig1 RNA sensor RIG-1 acts_upstream_of_or_within ISO (PMID:21703541) RGD PMID:21703541 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Ripk2 receptor-interacting serine-threonine kinase 2 acts_upstream_of_or_within ISO MGI:2660793 (PMID:11894098) RGD PMID:11894098 NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
JBrowse link
G Slc3a2 solute carrier family 3 member 2 acts_upstream_of_or_within
involved_in
ISO
IEA
(PMID:21266579)
GO_REF:0000107
RGD
Ensembl
PMID:21266579 GO_REF:0000107 NCBI chr 1:205,604,468...205,618,931
Ensembl chr 1:205,604,468...205,618,931
JBrowse link
G Stat1 signal transducer and activator of transcription 1 acts_upstream_of_or_within ISO (PMID:12872135) RGD PMID:12872135 NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540
JBrowse link
G Ticam1 TIR domain containing adaptor molecule 1 acts_upstream_of_or_within
involved_in
ISO (PMID:21266579)
(PMID:21703541)
MGI:2679794|MGI:3029019 (PMID:12855817), (PMID:12872135), (PMID:21703541)
RGD PMID:12855817 PMID:12872135 PMID:21266579 PMID:21703541 NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within ISO (PMID:21266579)
MGI:3690535 (PMID:12855817)
RGD PMID:12855817 PMID:21266579 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
cellular response to exogenous dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 involved_in ISO
IEA
(PMID:25204797)
GO_REF:0000107
RGD
Ensembl
PMID:25204797 GO_REF:0000107 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Cgas cyclic GMP-AMP synthase involved_in ISO
IBA
(MGI:5487472|PMID:23258413), (MGI:5897489|PMID:28363908), (MGI:5897502|PMID:28214358), (MGI:5908326|PMID:24077100)
(PMID:23258413), (PMID:24077100), (PMID:28214358), (PMID:28363908)
GO_REF:0000033
RGD
GO_Central
PMID:23258413 PMID:24077100 PMID:28214358 PMID:28363908 GO_REF:0000033 MGI:5487472 MGI:5897489 MGI:5897502 MGI:5908326 NCBI chr 8:79,292,282...79,306,998
Ensembl chr 8:79,294,511...79,305,496
JBrowse link
G Ciita class II, major histocompatibility complex, transactivator IEP RGD PMID:10051633 RGD:7242894 NCBI chr10:5,139,947...5,187,493
Ensembl chr10:5,140,178...5,187,440
JBrowse link
G Colec12 collectin sub-family member 12 involved_in
NOT|involved_in
ISO (PMID:25204797) RGD PMID:25204797 NCBI chr18:732,950...920,620
Ensembl chr18:732,950...920,618
JBrowse link
G Dhx9 DExH-box helicase 9 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr13:65,602,322...65,639,098
Ensembl chr13:65,602,323...65,639,069
JBrowse link
G Flot1 flotillin 1 involved_in ISO (PMID:25204797) RGD PMID:25204797 NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
JBrowse link
G Ifih1 interferon induced with helicase C domain 1 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr 3:47,228,980...47,275,403
Ensembl chr 3:47,227,364...47,275,456
JBrowse link
G Ifnb1 interferon beta 1 IEP RGD PMID:18223009 RGD:5128810 NCBI chr 5:103,020,758...103,021,595
Ensembl chr 5:103,020,969...103,021,523
JBrowse link
G Irf1 interferon regulatory factor 1 IEP RGD PMID:11694343 RGD:5128789 NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166
JBrowse link
G Irf3 interferon regulatory factor 3 IEP RGD PMID:18223009 RGD:5128810 NCBI chr 1:95,479,966...95,484,926
Ensembl chr 1:95,479,821...95,484,935
JBrowse link
G Mavs mitochondrial antiviral signaling protein involved_in ISS
ISO
GO_REF:0000024
(PMID:16127453), (PMID:21957149)
UniProt
RGD
PMID:16127453 PMID:21957149 GO_REF:0000024 NCBI chr 3:118,451,650...118,466,094
Ensembl chr 3:118,451,743...118,466,094
JBrowse link
G Mul1 mitochondrial E3 ubiquitin protein ligase 1 involved_in ISO (PMID:23399697) RGD PMID:23399697 NCBI chr 5:150,652,812...150,661,863
Ensembl chr 5:150,652,812...150,661,863
JBrowse link
G Pqbp1 polyglutamine binding protein 1 involved_in ISS
ISO
GO_REF:0000024
(PMID:26046437)
UniProt
RGD
PMID:26046437 GO_REF:0000024 NCBI chr  X:14,603,516...14,608,091
Ensembl chr  X:14,603,539...14,608,087
JBrowse link
G Ralb RAS like proto-oncogene B involved_in ISO
IEA
(PMID:24056301)
GO_REF:0000107
RGD
Ensembl
PMID:24056301 GO_REF:0000107 NCBI chr13:30,588,036...30,624,199
Ensembl chr13:30,588,033...30,624,202
JBrowse link
G Rig1 RNA sensor RIG-1 involved_in ISO (PMID:21957149) RGD PMID:21957149 NCBI chr 5:55,321,351...55,369,947
Ensembl chr 5:55,321,235...55,370,819
JBrowse link
G Sting1 stimulator of interferon response cGAMP interactor 1 involved_in ISO
IEA
(PMID:18818105)
GO_REF:0000107
RGD
Ensembl
PMID:18818105 GO_REF:0000107 NCBI chr18:27,332,119...27,338,371
Ensembl chr18:27,332,119...27,338,335
JBrowse link
G Tlr3 toll-like receptor 3 acts_upstream_of_or_within IEP
IMP
ISO
(PMID:28970238) RGD PMID:28970238 PMID:20937230 PMID:15920723 RGD:5128701, RGD:2301737 NCBI chr16:46,821,980...46,837,900
Ensembl chr16:46,822,039...46,836,545
JBrowse link
G Zc3hav1 zinc finger CCCH-type containing, antiviral 1 acts_upstream_of_or_within ISO (PMID:21102435) RGD PMID:21102435 NCBI chr 4:67,012,129...67,062,428
Ensembl chr 4:67,012,185...67,062,428
JBrowse link
G Zcchc3 zinc finger CCHC-type containing 3 involved_in ISO
IBA
(PMID:30193849)
GO_REF:0000033
(MGI:6271678|PMID:30193849)
RGD
GO_Central
PMID:30193849 GO_REF:0000033 MGI:6271678 NCBI chr 3:140,872,460...140,875,292
Ensembl chr 3:140,872,460...140,882,408
JBrowse link
immune response involved in response to exogenous dsRNA term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hcfc2 host cell factor C2 involved_in
acts_upstream_of_or_within
IEA
ISO
GO_REF:0000107
MGI:5445585 (PMID:28970238)
Ensembl
RGD
PMID:28970238 GO_REF:0000107 NCBI chr 7:20,983,986...21,019,826
Ensembl chr 7:20,991,017...21,019,801
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20133
    response to stimulus 10609
      response to chemical 5883
        response to nitrogen compound 1505
          response to dsRNA 54
            response to exogenous dsRNA 44
              cellular response to exogenous dsRNA 19
              immune response involved in response to exogenous dsRNA 1
paths to the root