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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation


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positive regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr12:59,431,834...59,449,701
Ensembl chr12:59,393,220...59,449,692
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr12:17,251,361...17,306,308
Ensembl chr12:17,252,018...17,306,319
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 4:91,118,867...91,125,448
Ensembl chr 4:91,118,879...91,125,437
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 4:89,242,467...89,246,344
Ensembl chr 4:89,242,459...89,247,065
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase IEA Ensembl GO_REF:0000107 NCBI chr 6:84,809,534...84,830,401
Ensembl chr 6:84,809,542...84,830,361
JBrowse link
G GAB2 GRB2 associated binding protein 2 ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr 9:12,663,658...12,851,423
Ensembl chr 9:12,656,882...12,851,402
JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:42,898,431...42,905,939
Ensembl chr  X:42,898,442...42,905,976
JBrowse link
G GATA2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chr13:71,981,139...71,997,626
Ensembl chr13:71,984,063...71,997,622
JBrowse link
G IL13 interleukin 13 IEA Ensembl GO_REF:0000107 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093
JBrowse link
G IL4 interleukin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365
JBrowse link
G IL4R interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 3:19,526,343...19,576,792
Ensembl chr 3:19,523,564...19,576,544
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr 2:11,400,415...11,420,314
Ensembl chr 2:11,400,420...11,420,299
JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr15:132,504,669...132,509,688
Ensembl chr15:132,506,474...132,509,673
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr12:52,073,913...52,087,804
Ensembl chr12:52,073,896...52,087,809
JBrowse link
G SPHK2 sphingosine kinase 2 IEA Ensembl GO_REF:0000107 NCBI chr 6:53,982,911...53,986,779
Ensembl chr 6:53,979,012...53,986,770
JBrowse link
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 1:268,116,124...268,205,805
Ensembl chr 1:268,116,118...268,213,921
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 2:71,504,575...71,513,446
Ensembl chr 2:71,504,569...71,513,422
JBrowse link
G SYK spleen associated tyrosine kinase IEA
IBA
(PMID:21873635) Ensembl
GO_Central
PMID:21873635 GO_REF:0000107 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,712...2,161,172
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 6:71,919,557...71,921,345
Ensembl chr 6:71,919,495...71,932,254
JBrowse link
G PLA2G3 phospholipase A2 group III IEA Ensembl GO_REF:0000107 NCBI chr14:47,923,005...47,928,762
Ensembl chr14:47,923,787...47,928,810
JBrowse link
G SNX4 sorting nexin 4 IEA Ensembl GO_REF:0000107 NCBI chr13:134,824,028...134,903,765
Ensembl chr13:134,824,043...134,905,359
JBrowse link
G VAMP7 vesicle associated membrane protein 7 IEA Ensembl GO_REF:0000107 NCBI chr  X:125,863,266...125,917,232
Ensembl chr  X:125,863,291...125,917,227
JBrowse link
G VAMP8 vesicle associated membrane protein 8 ISO (PMID:18253931) UniProtKB PMID:18253931 NCBI chr 3:59,187,900...59,193,165 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16531
    immune system process 2304
      positive regulation of immune system process 801
        positive regulation of immune response 462
          positive regulation of mast cell activation involved in immune response 23
            positive regulation of mast cell degranulation 23
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in other organism 0
Path 2
Term Annotations click to browse term
  biological_process 16531
    localization 5929
      establishment of localization 4425
        transport 4264
          secretion 1073
            secretion by cell 909
              exocytosis 392
                regulated exocytosis 271
                  leukocyte degranulation 78
                    regulation of leukocyte degranulation 54
                      positive regulation of leukocyte degranulation 33
                        positive regulation of mast cell degranulation 23
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in other organism 0
paths to the root