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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation


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positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor acts_upstream_of_or_within IMP (PMID:11454903) MGI PMID:11454903 NCBI chr11:62,139,810...62,157,278
Ensembl chr11:62,139,810...62,157,279 		JBrowse link
G Adora3 adenosine A3 receptor acts_upstream_of_or_within IMP
IDA		 (PMID:12817016) MGI PMID:12817016 NCBI chr 3:105,811,737...105,816,244
Ensembl chr 3:105,778,174...105,816,242 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 involved_in ISO RGD
MGI		 PMID:18209484 GO_REF:0000096 MGI:4417868 RGD:5130941 NCBI chr11:104,021,289...104,066,349
Ensembl chr11:104,023,681...104,066,349 		JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide acts_upstream_of_or_within IDA (PMID:9000133) MGI PMID:9000133 NCBI chr 1:173,048,836...173,054,799
Ensembl chr 1:173,048,851...173,054,781 		JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide acts_upstream_of_or_within IDA
IMP		 (PMID:14764707) MGI PMID:14764707 NCBI chr 1:171,057,141...171,061,918
Ensembl chr 1:171,057,141...171,061,934 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase involved_in IDA (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chr 4:132,701,406...132,729,204
Ensembl chr 4:132,701,406...132,729,221 		JBrowse link
G Gab2 growth factor receptor bound protein 2-associated protein 2 involved_in IMP (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr 7:96,730,958...96,958,158
Ensembl chr 7:96,730,793...96,958,153 		JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO RGD
MGI		 PMID:22390417 GO_REF:0000096 MGI:4417868 RGD:9587812 NCBI chr  X:7,825,504...7,842,844
Ensembl chr  X:7,825,499...7,844,310 		JBrowse link
G Gata2 GATA binding protein 2 involved_in ISO RGD
MGI		 PMID:22390417 GO_REF:0000096 MGI:4417868 RGD:9587812 NCBI chr 6:88,170,873...88,184,014
Ensembl chr 6:88,170,873...88,184,014 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) acts_upstream_of_or_within IDA (PMID:12817016), (PMID:14764707), (PMID:9000133) MGI PMID:9000133 PMID:12817016 PMID:14764707
G Il13 interleukin 13 acts_upstream_of_or_within IGI
IMP		 (PMID:15944273) MGI PMID:15944273 NCBI chr11:53,522,150...53,525,529
Ensembl chr11:53,522,151...53,525,529 		JBrowse link
G Il4 interleukin 4 acts_upstream_of_or_within IMP
IGI		 (PMID:15944273) MGI PMID:15944273 NCBI chr11:53,503,287...53,509,492
Ensembl chr11:53,493,809...53,509,496 		JBrowse link
G Il4ra interleukin 4 receptor, alpha acts_upstream_of_or_within IMP (PMID:15944273) MGI PMID:15944273 NCBI chr 7:125,151,443...125,178,646
Ensembl chr 7:125,151,292...125,178,646 		JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 involved_in ISO RGD
MGI		 PMID:16177098 GO_REF:0000096 MGI:4417868 RGD:1578516 NCBI chr19:11,592,881...11,601,154
Ensembl chr19:11,592,887...11,601,083 		JBrowse link
G Nppc natriuretic peptide type C involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 1:86,594,015...86,598,295
Ensembl chr 1:86,594,013...86,598,293 		JBrowse link
G Pld2 phospholipase D2 involved_in ISO RGD
MGI		 PMID:16861349 GO_REF:0000096 MGI:4417868 RGD:2299903 NCBI chr11:70,430,318...70,448,936
Ensembl chr11:70,430,890...70,448,936 		JBrowse link
G Sphk2 sphingosine kinase 2 involved_in IMP (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chr 7:45,358,887...45,367,426
Ensembl chr 7:45,358,891...45,367,426 		JBrowse link
G Stxbp1 syntaxin binding protein 1 involved_in ISO RGD
MGI		 PMID:23487749 GO_REF:0000096 MGI:4417868 RGD:12904029 NCBI chr 2:32,677,619...32,737,249
Ensembl chr 2:32,677,614...32,737,257 		JBrowse link
G Stxbp2 syntaxin binding protein 2 involved_in ISO RGD
MGI		 PMID:23487749 GO_REF:0000096 MGI:4417868 RGD:12904029 NCBI chr 8:3,680,960...3,693,998
Ensembl chr 8:3,680,955...3,693,644 		JBrowse link
G Syk spleen tyrosine kinase acts_upstream_of_or_within
involved_in		 ISO
IMP		 (PMID:9000133) RGD
MGI		 PMID:9000133 PMID:16861349 GO_REF:0000096 MGI:4417868 RGD:2299903 NCBI chr13:52,736,670...52,802,828
Ensembl chr13:52,737,209...52,802,828 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide type A involved_in ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 4:148,085,179...148,086,531
Ensembl chr 4:148,085,179...148,086,536 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in IMP
ISO		 (MGI:5492190|PMID:23624557) UniProt
MGI		 PMID:23624557 GO_REF:0000119 MGI:4834177 MGI:5492190 NCBI chr11:3,438,158...3,449,346
Ensembl chr11:3,438,284...3,449,350 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr16:33,071,826...33,119,932
Ensembl chr16:33,071,812...33,120,639 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO MGI GO_REF:0000119 MGI:4834177
G Vamp8 vesicle-associated membrane protein 8 involved_in ISO MGI GO_REF:0000119 MGI:4834177 NCBI chr 6:72,362,204...72,367,650
Ensembl chr 6:72,362,206...72,367,686 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28573
    immune system process 3134
      immune effector process 874
        positive regulation of immune effector process 329
          positive regulation of leukocyte degranulation 39
            positive regulation of mast cell degranulation 25
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in another organism 0
Path 2
Term Annotations click to browse term
  biological_process 28573
    localization 5524
      establishment of localization 4823
        transport 4507
          secretion 1218
            secretion by cell 1025
              exocytosis 413
                regulated exocytosis 278
                  leukocyte degranulation 105
                    regulation of leukocyte degranulation 59
                      positive regulation of leukocyte degranulation 39
                        positive regulation of mast cell degranulation 25
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in another organism 0
paths to the root