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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation


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positive regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor IMP (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr11:62,248,984...62,266,452
Ensembl chr11:62,248,984...62,266,453
JBrowse link
G Adora3 adenosine A3 receptor IMP
IDA
(MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr 3:105,904,421...105,908,928
Ensembl chr 3:105,870,858...105,908,926
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:104,130,463...104,175,523
Ensembl chr11:104,132,855...104,175,523
JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide IDA (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:173,221,269...173,227,232
Ensembl chr 1:173,221,284...173,227,214
JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide IMP
IDA
(MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 1:171,229,572...171,234,349
Ensembl chr 1:171,229,572...171,234,365
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase IDA (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chr 4:132,974,095...133,001,893
Ensembl chr 4:132,974,095...133,001,910
JBrowse link
G Gab2 growth factor receptor bound protein 2-associated protein 2 IMP (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr 7:97,081,751...97,308,951
Ensembl chr 7:97,081,586...97,308,946
JBrowse link
G Gata1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:7,959,260...7,976,663
Ensembl chr  X:7,959,260...7,978,071
JBrowse link
G Gata2 GATA binding protein 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 6:88,193,891...88,207,032
Ensembl chr 6:88,193,891...88,207,032
JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) IDA (MGI:2664591|PMID:12817016), (MGI:3029067|PMID:14764707), (MGI:85068|PMID:9000133) MGI PMID:9000133 PMID:12817016 PMID:14764707 MGI:2664591 MGI:3029067 MGI:85068
G Il13 interleukin 13 IGI
IMP
(MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702
JBrowse link
G Il4 interleukin 4 IMP
IBA
IGI
(MGI:3589858|PMID:15944273)
(MGI:6201960|PMID:21873635)
MGI
GO_Central
PMID:15944273 PMID:21873635 MGI:3589858 MGI:6201960 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669
JBrowse link
G Il4ra interleukin 4 receptor, alpha IMP (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 7:125,552,271...125,579,474
Ensembl chr 7:125,552,120...125,579,474
JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:11,615,517...11,623,790
Ensembl chr19:11,615,523...11,623,719
JBrowse link
G Nppc natriuretic peptide type C ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 1:86,666,293...86,670,573
Ensembl chr 1:86,666,291...86,670,571
JBrowse link
G Pld2 phospholipase D2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:70,539,492...70,558,110
Ensembl chr11:70,540,064...70,558,110
JBrowse link
G Sphk2 sphingosine kinase 2 IMP (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chr 7:45,709,463...45,718,002
Ensembl chr 7:45,709,467...45,718,002
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:32,787,607...32,847,237
Ensembl chr 2:32,787,602...32,847,245
JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 8:3,630,960...3,643,998
Ensembl chr 8:3,630,955...3,643,644
JBrowse link
G Syk spleen tyrosine kinase IBA
ISO
IMP
(MGI:6201960|PMID:21873635)
(MGI:85068|PMID:9000133)
GO_Central
MGI
PMID:9000133 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 MGI:85068 NCBI chr13:52,582,610...52,648,792
Ensembl chr13:52,583,173...52,648,792
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide type A ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079
JBrowse link
G Pla2g3 phospholipase A2, group III IMP
ISO
(MGI:5492190|PMID:23624557) UniProt
MGI
PMID:23624557 GO_REF:0000096 MGI:4834177 MGI:5492190 NCBI chr11:3,488,158...3,499,346
Ensembl chr11:3,488,284...3,499,350
JBrowse link
G Snx4 sorting nexin 4 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr16:33,251,456...33,299,562
Ensembl chr16:33,251,442...33,300,269
JBrowse link
G Vamp7 vesicle-associated membrane protein 7 ISO MGI GO_REF:0000096 MGI:4834177
G Vamp8 vesicle-associated membrane protein 8 ISO MGI GO_REF:0000096 MGI:4834177 NCBI chr 6:72,385,221...72,390,667
Ensembl chr 6:72,385,223...72,390,703
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23351
    immune system process 2935
      positive regulation of immune system process 1032
        positive regulation of immune response 678
          positive regulation of mast cell activation involved in immune response 25
            positive regulation of mast cell degranulation 25
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in other organism 0
Path 2
Term Annotations click to browse term
  biological_process 23351
    localization 6246
      establishment of localization 4683
        transport 4523
          secretion 1122
            secretion by cell 930
              exocytosis 404
                regulated exocytosis 275
                  leukocyte degranulation 86
                    regulation of leukocyte degranulation 57
                      positive regulation of leukocyte degranulation 37
                        positive regulation of mast cell degranulation 25
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in other organism 0
paths to the root