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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of mast cell degranulation
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Accession:GO:0043306 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
Synonyms:exact_synonym: positive regulation of mast cell granule exocytosis;   up regulation of mast cell degranulation;   upregulation of mast cell degranulation
 narrow_synonym: activation of mast cell degranulation;   stimulation of mast cell degranulation

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positive regulation of mast cell degranulation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr17:34,849,466...34,880,088 JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208 		JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:134,655,230...134,660,961
Ensembl chr 1:138,439,921...138,458,258 		JBrowse link
G FCER1G Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase ISO (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chr 1:26,872,781...26,895,751
Ensembl chr 1:27,918,758...27,941,678 		JBrowse link
G GAB2 GRB2 associated binding protein 2 ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr11:73,275,360...73,478,272
Ensembl chr11:76,896,691...76,967,007 		JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:41,088,724...41,092,190
Ensembl chr  X:48,945,394...48,953,126 		JBrowse link
G GATA2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035 		JBrowse link
G IL13 interleukin 13 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548 		JBrowse link
G IL4 interleukin 4 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581 		JBrowse link
G IL4R interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr11:55,318,843...55,326,779
Ensembl chr11:58,764,911...58,772,567 		JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr2B:119,148,774...119,153,381
Ensembl chr2B:237,936,939...237,941,244 		JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr17:4,853,919...4,870,254
Ensembl chr17:4,843,217...4,858,425 		JBrowse link
G SPHK2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chr19:45,620,980...45,631,786
Ensembl chr19:54,213,166...54,224,767 		JBrowse link
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152 		JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr19:6,926,833...6,937,385
Ensembl chr19:7,781,830...7,792,038 		JBrowse link
G SYK spleen associated tyrosine kinase ISO (MGI:85068|PMID:9000133) RGD
MGI		 PMID:9000133 PMID:16861349 MGI:85068 RGD:2299903 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G PLA2G3 phospholipase A2 group III ISO (PMID:23624557)
(MGI:5492190|PMID:23624557)		 UniProt PMID:23624557 MGI:5492190 NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160 		JBrowse link
G SNX4 sorting nexin 4 ISO (PMID:18253931) UniProtKB PMID:18253931 NCBI chr 3:122,578,527...122,652,007
Ensembl chr 3:129,443,369...129,515,917 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 ISO (PMID:18253931) UniProtKB PMID:18253931 NCBI chr  X:145,362,432...145,425,097
Ensembl chr  X:155,257,185...155,320,215 		JBrowse link
G VAMP8 vesicle associated membrane protein 8 ISO (PMID:18253931) UniProtKB PMID:18253931 NCBI chr2A:85,627,678...85,632,205
Ensembl chr2A:87,180,681...87,185,195 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12593
    immune system process 2083
      positive regulation of immune system process 756
        positive regulation of immune response 428
          positive regulation of mast cell activation involved in immune response 23
            positive regulation of mast cell degranulation 23
              positive regulation of histamine secretion by mast cell 5
              positive regulation of mast cell degranulation in other organism 0
Path 2
Term Annotations click to browse term
  biological_process 12593
    localization 4951
      establishment of localization 3534
        transport 3371
          secretion 982
            secretion by cell 827
              exocytosis 325
                regulated exocytosis 248
                  leukocyte degranulation 73
                    regulation of leukocyte degranulation 51
                      positive regulation of leukocyte degranulation 32
                        positive regulation of mast cell degranulation 23
                          positive regulation of histamine secretion by mast cell 5
                          positive regulation of mast cell degranulation in other organism 0
paths to the root