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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of mast cell degranulation
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Accession:GO:0043304 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell degranulation.
Synonyms:exact_synonym: regulation of mast cell granule exocytosis


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regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CUNH12orf4 chromosome unknown C12orf4 homolog ISO PMID:25122211 UniProt PMID:25122211 RGD:10047193 NCBI chrNW_004936606:4,660,203...4,697,065 JBrowse link
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:19001085) UniProt PMID:19001085 NCBI chrNW_004936483:16,123,938...16,135,044 JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO (MGI:3703139|PMID:16272347) UniProt PMID:16272347 MGI:3703139 NCBI chrNW_004936496:2,578,598...2,698,165 JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO (MGI:5298334|PMID:21063107) UniProt PMID:21063107 MGI:5298334 NCBI chrNW_004936694:1,444,819...1,487,628 JBrowse link
G Rac2 Rac family small GTPase 2 ISO (MGI:3655336|PMID:10843388) CACAO PMID:10843388 MGI:3655336 NCBI chrNW_004936492:3,726,375...3,737,961 JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chrNW_004936588:4,688,221...4,696,075 JBrowse link
G Unc13d unc-13 homolog D involved_in ISO (PMID:15548590) UniProt PMID:15548590 NCBI chrNW_004936594:1,008,215...1,023,023 JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd84 CD84 molecule involved_in ISO (PMID:22068234) UniProt PMID:22068234 NCBI chrNW_004936740:111,296...133,847 JBrowse link
G Foxf1 forkhead box F1 ISO (MGI:4367570|PMID:18421012) MGI PMID:18421012 MGI:4367570 NCBI chrNW_004943883:4...1,756 JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chrNW_004936492:5,042,353...5,049,216 JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004936499:860,179...883,884 JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chrNW_004936538:4,034,467...4,050,240 JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO (MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:3050742 NCBI chrNW_004936543:7,405,070...7,447,940 JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004936474:671,362...673,610 JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (MGI:5492190|PMID:23624557)
(PMID:23624557)
UniProt PMID:23624557 MGI:5492190 NCBI chrNW_004936755:307,166...312,683 JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004937215:127,074...137,281 JBrowse link
G Vamp7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004936958:345,055...393,384 JBrowse link
G Vamp8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004936712:1,688,126...1,689,742 JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chrNW_004936821:583,463...608,189 JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chrNW_004936541:2,288,847...2,333,129 JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chrNW_004936740:1,201,370...1,206,871 JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chrNW_004936903:514,278...517,975 JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISO (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chrNW_004936474:11,897,998...11,919,153 JBrowse link
G Gab2 GRB2 associated binding protein 2 ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chrNW_004936498:6,775,170...6,835,680 JBrowse link
G Gata1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004936721:742,862...750,843 JBrowse link
G Gata2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004936798:406,258...414,785 JBrowse link
G Il13 interleukin 13 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004936647:2,529,933...2,532,503 JBrowse link
G Il4 interleukin 4 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004936647:2,510,457...2,518,576 JBrowse link
G Il4r interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004936501:11,025,590...11,058,807 JBrowse link
G LOC101973578 adenosine receptor A3 ISO (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chrNW_004936690:152,777...168,411 JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004936581:2,743,133...2,751,925 JBrowse link
G Nppc natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004936525:5,092,675...5,099,344 JBrowse link
G Pld2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chrNW_004936677:2,870,664...2,883,545 JBrowse link
G Sphk2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chrNW_004936664:2,668,708...2,676,608 JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004936487:15,300,758...15,367,475 JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004936588:4,688,221...4,696,075 JBrowse link
G Syk spleen associated tyrosine kinase ISO (MGI:85068|PMID:9000133) RGD
MGI
PMID:9000133 PMID:16861349 MGI:85068 RGD:2299903 NCBI chrNW_004936780:1,553,605...1,601,036 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12053
    cellular process 11242
      cellular localization 2358
        regulation of cellular localization 879
          regulation of mast cell degranulation 36
            modulation of mast cell degranulation in other organism + 0
            negative regulation of mast cell degranulation 6
            positive regulation of mast cell degranulation + 24
Path 2
Term Annotations click to browse term
  biological_process 12053
    localization 4806
      establishment of localization 3442
        transport 3278
          secretion 953
            secretion by cell 808
              exocytosis 320
                regulated exocytosis 242
                  leukocyte degranulation 68
                    regulation of leukocyte degranulation 48
                      regulation of mast cell degranulation 36
                        modulation of mast cell degranulation in other organism + 0
                        negative regulation of mast cell degranulation 6
                        positive regulation of mast cell degranulation + 24
paths to the root