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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mast cell degranulation
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Accession:GO:0043304 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell degranulation.
Synonyms:exact_synonym: regulation of mast cell granule exocytosis

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regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,123...14,746,414 		JBrowse link
G C5H12orf4 chromosome 5 C12orf4 homolog ISO PMID:25122211 UniProt PMID:25122211 RGD:10047193 NCBI chr 5:65,896,750...65,944,183
Ensembl chr 5:65,897,541...65,944,185 		JBrowse link
G FER FER tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:113,774,120...114,207,307
Ensembl chr 2:113,774,412...114,206,930 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:53,472,947...53,485,084
Ensembl chr 7:53,472,946...53,485,082 		JBrowse link
G LOC100516957 adhesion G protein-coupled receptor E2-like involved_in ISO (PMID:26841242) UniProt PMID:26841242 NCBI chr 2:63,853,304...63,900,460 JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO		 (PMID:21873635)
(MGI:3703139|PMID:16272347)		 GO_Central
UniProt		 PMID:16272347 PMID:21873635 MGI:3703139 NCBI chr 4:75,793,273...75,903,710
Ensembl chr 4:75,786,099...75,868,591 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA
ISO		 (MGI:5298334|PMID:21063107) Ensembl
UniProt		 PMID:21063107 GO_REF:0000107 MGI:5298334 NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,429,931...39,532,583 		JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA
ISO		 (MGI:3655336|PMID:10843388) Ensembl
CACAO		 PMID:10843388 GO_REF:0000107 MGI:3655336 NCBI chr 5:10,553,986...10,571,082
Ensembl chr 5:10,553,433...10,573,017 		JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chr 2:71,504,575...71,513,446
Ensembl chr 2:71,504,569...71,513,422 		JBrowse link
G UNC13D unc-13 homolog D involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:5,573,428...5,598,914
Ensembl chr12:5,573,667...5,589,088 		JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (MGI:3721168|PMID:12874256)
(PMID:16339535)		 MGI
UniProt		 PMID:12874256 PMID:16339535 MGI:3721168 NCBI chr12:6,665,578...6,681,329 JBrowse link
G CD84 CD84 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:89,932,020...89,980,476
Ensembl chr 4:89,932,202...89,969,666 		JBrowse link
G FOXF1 forkhead box F1 involved_in IEA
ISO		 (MGI:4367570|PMID:18421012) Ensembl
MGI		 PMID:18421012 GO_REF:0000107 MGI:4367570 NCBI chr 6:2,579,348...2,598,122
Ensembl chr 6:2,592,993...2,597,659 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626
G IL13RA2 interleukin 13 receptor subunit alpha 2 involved_in IEA
ISO		 (MGI:3589858|PMID:15944273) Ensembl
MGI		 PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:94,402,665...94,455,609
Ensembl chr  X:94,402,675...94,439,060 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chr12:44,155,079...44,173,634 JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 involved_in IEA
ISO		 (MGI:3050742|PMID:15235600) Ensembl
MGI		 PMID:15235600 GO_REF:0000107 MGI:3050742 NCBI chr 3:16,308,112...16,376,604
Ensembl chr 3:16,308,112...16,376,587 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 6:71,919,557...71,921,345
Ensembl chr 6:71,919,495...71,932,254 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA
ISO		 (MGI:5492190|PMID:23624557) Ensembl
UniProt		 PMID:23624557 GO_REF:0000107 MGI:5492190 NCBI chr14:47,923,005...47,928,762
Ensembl chr14:47,923,787...47,928,810 		JBrowse link
G SNX4 sorting nexin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:134,824,028...134,903,765
Ensembl chr13:134,824,043...134,905,359 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:125,863,266...125,917,232
Ensembl chr  X:125,863,291...125,917,227 		JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr 3:59,187,900...59,193,165 JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr12:59,431,834...59,449,701
Ensembl chr12:59,393,220...59,449,692 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr12:17,251,361...17,306,308
Ensembl chr12:17,252,018...17,306,319 		JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 4:91,118,867...91,125,448
Ensembl chr 4:91,118,879...91,125,437 		JBrowse link
G FCER1G Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 4:89,242,467...89,246,344
Ensembl chr 4:89,242,459...89,247,065 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in IEA
ISO		 (MGI:5294498|PMID:21746961) Ensembl
UniProt		 PMID:21746961 GO_REF:0000107 MGI:5294498 NCBI chr 6:84,809,534...84,830,401
Ensembl chr 6:84,809,542...84,830,361 		JBrowse link
G GAB2 GRB2 associated binding protein 2 ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr 9:12,663,658...12,851,423
Ensembl chr 9:12,656,882...12,851,402 		JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:42,898,431...42,905,939
Ensembl chr  X:42,898,442...42,905,976 		JBrowse link
G GATA2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chr13:71,981,139...71,997,626
Ensembl chr13:71,984,063...71,997,622 		JBrowse link
G IL13 interleukin 13 involved_in IEA
ISO		 (MGI:3589858|PMID:15944273) Ensembl
MGI		 PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr 2:134,972,099...134,976,672
Ensembl chr 2:134,972,623...134,975,093 		JBrowse link
G IL4 interleukin 4 involved_in IBA
ISO		 (PMID:21873635)
(MGI:3589858|PMID:15944273)		 GO_Central
MGI		 PMID:15944273 PMID:21873635 MGI:3589858 NCBI chr 2:134,986,817...134,994,365
Ensembl chr 2:134,986,817...134,994,365 		JBrowse link
G IL4R interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 3:19,526,343...19,576,792
Ensembl chr 3:19,523,564...19,576,544 		JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr 2:11,400,415...11,420,314
Ensembl chr 2:11,400,420...11,420,299 		JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr15:132,504,669...132,509,688
Ensembl chr15:132,506,474...132,509,673 		JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr12:52,073,913...52,087,804
Ensembl chr12:52,073,896...52,087,809 		JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA
ISO		 (MGI:3703830|PMID:17346996) Ensembl
UniProt		 PMID:17346996 GO_REF:0000107 MGI:3703830 NCBI chr 6:53,982,911...53,986,779
Ensembl chr 6:53,979,012...53,986,770 		JBrowse link
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 1:268,116,124...268,205,805
Ensembl chr 1:268,116,118...268,213,921 		JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 2:71,504,575...71,513,446
Ensembl chr 2:71,504,569...71,513,422 		JBrowse link
G SYK spleen associated tyrosine kinase involved_in IEA
ISO
IBA		 (MGI:85068|PMID:9000133)
(PMID:21873635)		 Ensembl
RGD
MGI
GO_Central		 PMID:9000133 PMID:16861349 PMID:21873635 GO_REF:0000107 MGI:85068 RGD:2299903 NCBI chr14:2,103,706...2,160,886
Ensembl chr14:2,056,712...2,161,172 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16538
    cellular process 15825
      cellular localization 2795
        regulation of cellular localization 909
          regulation of mast cell degranulation 39
            modulation of mast cell degranulation in other organism + 0
            negative regulation of mast cell degranulation 7
            positive regulation of mast cell degranulation + 23
Path 2
Term Annotations click to browse term
  biological_process 16538
    localization 5935
      establishment of localization 4425
        transport 4263
          secretion 1074
            secretion by cell 909
              exocytosis 390
                regulated exocytosis 273
                  leukocyte degranulation 79
                    regulation of leukocyte degranulation 55
                      regulation of mast cell degranulation 39
                        modulation of mast cell degranulation in other organism + 0
                        negative regulation of mast cell degranulation 7
                        positive regulation of mast cell degranulation + 23
paths to the root