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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mast cell degranulation
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Accession:GO:0043304 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell degranulation.
Synonyms:exact_synonym: regulation of mast cell granule exocytosis

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regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Blk B lymphoid kinase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr14:63,372,837...63,417,187
Ensembl chr14:63,372,836...63,417,037 		JBrowse link
G D6Wsu163e DNA segment, Chr 6, Wayne State University 163, expressed ISO
IBA		 (MGI:6201960|PMID:21873635) MGI
GO_Central		 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 NCBI chr 6:126,939,966...126,975,704
Ensembl chr 6:126,939,962...126,975,967 		JBrowse link
G Fer fer (fms/fps related) protein kinase IBA (MGI:6201960|PMID:21873635) GO_Central PMID:21873635 MGI:6201960 NCBI chr17:63,862,073...64,146,519
Ensembl chr17:63,863,062...64,139,496 		JBrowse link
G Fes feline sarcoma oncogene involved_in ISO
IBA		 (PMID:19001085)
(MGI:6201960|PMID:21873635)		 MGI
UniProt
GO_Central		 PMID:19001085 PMID:21873635 GO_REF:0000096 MGI:4834177 MGI:6201960 NCBI chr 7:80,377,758...80,387,954
Ensembl chr 7:80,377,756...80,387,946 		JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase IBA
IMP		 (MGI:6201960|PMID:21873635)
(MGI:3703139|PMID:16272347)		 GO_Central
UniProt		 PMID:16272347 PMID:21873635 MGI:3703139 MGI:6201960 NCBI chr 4:3,678,068...3,791,612
Ensembl chr 4:3,678,115...3,813,122 		JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 IMP (MGI:5298334|PMID:21063107) UniProt PMID:21063107 MGI:5298334 NCBI chr17:24,073,680...24,155,619
Ensembl chr17:24,073,680...24,150,924 		JBrowse link
G Rac2 Rac family small GTPase 2 IMP (MGI:3655336|PMID:10843388) CACAO PMID:10843388 MGI:3655336 NCBI chr15:78,559,169...78,572,783
Ensembl chr15:78,559,167...78,572,783 		JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 8:3,630,960...3,643,998
Ensembl chr 8:3,630,955...3,643,644 		JBrowse link
G Unc13d unc-13 homolog D involved_in ISO (PMID:15548590) MGI
UniProt		 PMID:15548590 GO_REF:0000096 MGI:4834177 NCBI chr11:116,062,095...116,078,495
Ensembl chr11:116,062,095...116,077,961 		JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300A molecule involved_in IDA
ISO		 (MGI:3721168|PMID:12874256)
(PMID:16339535)		 MGI
UniProt		 PMID:12874256 PMID:16339535 GO_REF:0000096 MGI:3721168 MGI:4834177 NCBI chr11:114,889,152...114,901,946
Ensembl chr11:114,890,041...114,904,654 		JBrowse link
G Cd84 CD84 antigen involved_in ISO (PMID:22068234) MGI
UniProt		 PMID:22068234 GO_REF:0000096 MGI:4834177 NCBI chr 1:171,839,697...171,890,718
Ensembl chr 1:171,839,697...171,890,718 		JBrowse link
G Foxf1 forkhead box F1 IMP (MGI:4367570|PMID:18421012) MGI PMID:18421012 MGI:4367570 NCBI chr 8:121,084,386...121,088,154
Ensembl chr 8:121,084,386...121,088,144 		JBrowse link
G Hmox1 heme oxygenase 1 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 8:75,093,618...75,100,593
Ensembl chr 8:75,093,621...75,100,589 		JBrowse link
G Il13ra2 interleukin 13 receptor, alpha 2 IMP (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr  X:147,383,478...147,429,192
Ensembl chr  X:147,383,476...147,429,192 		JBrowse link
G Lgals9 lectin, galactose binding, soluble 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chr11:78,962,979...78,984,924
Ensembl chr11:78,962,974...78,984,946 		JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 IMP (MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:3050742 NCBI chr 5:130,171,819...130,214,342
Ensembl chr 5:130,171,798...130,214,342 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide type A ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 4:148,000,722...148,002,074
Ensembl chr 4:148,000,722...148,002,079 		JBrowse link
G Pla2g3 phospholipase A2, group III involved_in IMP
ISO		 (MGI:5492190|PMID:23624557)
(PMID:23624557)		 UniProt
MGI
UniProt		 PMID:23624557 GO_REF:0000096 MGI:4834177 MGI:5492190 NCBI chr11:3,488,158...3,499,346
Ensembl chr11:3,488,284...3,499,350 		JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) MGI
UniProt		 PMID:18253931 GO_REF:0000096 MGI:4834177 NCBI chr16:33,251,456...33,299,562
Ensembl chr16:33,251,442...33,300,269 		JBrowse link
G Vamp7 vesicle-associated membrane protein 7 involved_in ISO (PMID:18253931) MGI
UniProt		 PMID:18253931 GO_REF:0000096 MGI:4834177
G Vamp8 vesicle-associated membrane protein 8 involved_in ISO (PMID:18253931) MGI
UniProt		 PMID:18253931 GO_REF:0000096 MGI:4834177 NCBI chr 6:72,385,221...72,390,667
Ensembl chr 6:72,385,223...72,390,703 		JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor IMP (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr11:62,248,984...62,266,452
Ensembl chr11:62,248,984...62,266,453 		JBrowse link
G Adora3 adenosine A3 receptor IMP
IDA		 (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr 3:105,904,421...105,908,928
Ensembl chr 3:105,870,858...105,908,926 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:104,130,463...104,175,523
Ensembl chr11:104,132,855...104,175,523 		JBrowse link
G Fcer1a Fc receptor, IgE, high affinity I, alpha polypeptide IDA (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:173,221,269...173,227,232
Ensembl chr 1:173,221,284...173,227,214 		JBrowse link
G Fcer1g Fc receptor, IgE, high affinity I, gamma polypeptide IMP
IDA		 (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 1:171,229,572...171,234,349
Ensembl chr 1:171,229,572...171,234,365 		JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase IDA (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chr 4:132,974,095...133,001,893
Ensembl chr 4:132,974,095...133,001,910 		JBrowse link
G Gab2 growth factor receptor bound protein 2-associated protein 2 IMP (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr 7:97,081,751...97,308,951
Ensembl chr 7:97,081,586...97,308,946 		JBrowse link
G Gata1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:7,959,260...7,976,663
Ensembl chr  X:7,959,260...7,978,071 		JBrowse link
G Gata2 GATA binding protein 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 6:88,193,891...88,207,032
Ensembl chr 6:88,193,891...88,207,032 		JBrowse link
G Igh-7 immunoglobulin heavy chain 7 (heavy chain of IgE) IDA (MGI:2664591|PMID:12817016), (MGI:3029067|PMID:14764707), (MGI:85068|PMID:9000133) MGI PMID:9000133 PMID:12817016 PMID:14764707 MGI:2664591 MGI:3029067 MGI:85068
G Il13 interleukin 13 IGI
IMP		 (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr11:53,631,323...53,634,702
Ensembl chr11:53,631,324...53,634,702 		JBrowse link
G Il4 interleukin 4 IMP
IBA
IGI		 (MGI:3589858|PMID:15944273)
(MGI:6201960|PMID:21873635)		 MGI
GO_Central		 PMID:15944273 PMID:21873635 MGI:3589858 MGI:6201960 NCBI chr11:53,612,460...53,618,665
Ensembl chr11:53,602,982...53,618,669 		JBrowse link
G Il4ra interleukin 4 receptor, alpha IMP (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 7:125,552,271...125,579,474
Ensembl chr 7:125,552,120...125,579,474 		JBrowse link
G Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr19:11,615,517...11,623,790
Ensembl chr19:11,615,523...11,623,719 		JBrowse link
G Nppc natriuretic peptide type C ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 1:86,666,293...86,670,573
Ensembl chr 1:86,666,291...86,670,571 		JBrowse link
G Pld2 phospholipase D2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr11:70,539,492...70,558,110
Ensembl chr11:70,540,064...70,558,110 		JBrowse link
G Sphk2 sphingosine kinase 2 IMP (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chr 7:45,709,463...45,718,002
Ensembl chr 7:45,709,467...45,718,002 		JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 2:32,787,607...32,847,237
Ensembl chr 2:32,787,602...32,847,245 		JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO MGI GO_REF:0000096 MGI:4417868 NCBI chr 8:3,630,960...3,643,998
Ensembl chr 8:3,630,955...3,643,644 		JBrowse link
G Syk spleen tyrosine kinase IBA
ISO
IMP		 (MGI:6201960|PMID:21873635)
(MGI:85068|PMID:9000133)		 GO_Central
MGI		 PMID:9000133 PMID:21873635 GO_REF:0000096 MGI:4417868 MGI:6201960 MGI:85068 NCBI chr13:52,582,610...52,648,792
Ensembl chr13:52,583,173...52,648,792 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23334
    cellular process 17484
      cellular localization 2886
        regulation of cellular localization 933
          regulation of mast cell degranulation 40
            modulation of mast cell degranulation in other organism + 0
            negative regulation of mast cell degranulation 7
            positive regulation of mast cell degranulation + 25
Path 2
Term Annotations click to browse term
  biological_process 23334
    localization 6249
      establishment of localization 4679
        transport 4518
          secretion 1128
            secretion by cell 935
              exocytosis 406
                regulated exocytosis 276
                  leukocyte degranulation 86
                    regulation of leukocyte degranulation 57
                      regulation of mast cell degranulation 40
                        modulation of mast cell degranulation in other organism + 0
                        negative regulation of mast cell degranulation 7
                        positive regulation of mast cell degranulation + 25
paths to the root