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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of mast cell degranulation
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Accession:GO:0043304 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell degranulation.
Synonyms:exact_synonym: regulation of mast cell granule exocytosis


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regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRE2 adhesion G protein-coupled receptor E2 involved_in IMP (PMID:26841242) UniProt PMID:26841242 NCBI chr19:14,732,392...14,778,560
Ensembl chr19:14,732,392...14,778,560
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 8:11,493,991...11,564,599
Ensembl chr 8:11,486,894...11,564,599
JBrowse link
G C12orf4 chromosome 12 open reading frame 4 involved_in ISS
ISO
IBA
PMID:25122211
(PMID:21873635)
UniProt
UniProt
GO_Central
PMID:21873635 PMID:25122211 GO_REF:0000024 RGD:10047193 NCBI chr12:4,487,735...4,538,508
Ensembl chr12:4,487,735...4,538,508
JBrowse link
G FER FER tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:108,746,085...109,196,841
Ensembl chr 5:108,747,841...109,196,841
JBrowse link
G FES FES proto-oncogene, tyrosine kinase involved_in IMP
IBA
(PMID:19001085)
(PMID:21873635)
UniProt
GO_Central
PMID:19001085 PMID:21873635 NCBI chr15:90,884,421...90,895,776
Ensembl chr15:90,883,695...90,895,776
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO
ISS
(PMID:21873635)
(MGI:3703139|PMID:16272347)
GO_Central
UniProt
UniProt
PMID:16272347 PMID:21873635 GO_REF:0000024 MGI:3703139 NCBI chr 8:55,876,041...56,014,169
Ensembl chr 8:55,879,835...56,014,169
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA
ISO
(MGI:5298334|PMID:21063107) Ensembl
UniProt
PMID:21063107 GO_REF:0000107 MGI:5298334 NCBI chr16:2,538,014...2,603,190
Ensembl chr16:2,537,979...2,603,188
JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA
ISO
(MGI:3655336|PMID:10843388) Ensembl
CACAO
PMID:10843388 GO_REF:0000107 MGI:3655336 NCBI chr22:37,225,270...37,244,269
Ensembl chr22:37,225,270...37,244,448
JBrowse link
G STXBP2 syntaxin binding protein 2 involved_in ISS
ISO
UniProt
RGD
PMID:12482918 GO_REF:0000024 RGD:2312429 NCBI chr19:7,637,110...7,647,873
Ensembl chr19:7,636,881...7,647,873
JBrowse link
G UNC13D unc-13 homolog D involved_in IMP (PMID:15548590) UniProt PMID:15548590 NCBI chr17:75,827,225...75,844,404
Ensembl chr17:75,827,225...75,844,552
Ensembl chr17:75,827,225...75,844,552
JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in IDA
ISO
(PMID:16339535)
(MGI:3721168|PMID:12874256)
UniProt
MGI
PMID:12874256 PMID:16339535 MGI:3721168 NCBI chr17:74,466,373...74,484,798
Ensembl chr17:74,466,399...74,484,794
JBrowse link
G CD84 CD84 molecule involved_in IDA (PMID:22068234) UniProt PMID:22068234 NCBI chr 1:160,541,098...160,579,515
Ensembl chr 1:160,541,095...160,579,516
JBrowse link
G FOXF1 forkhead box F1 involved_in IEA
ISO
(MGI:4367570|PMID:18421012) Ensembl
MGI
PMID:18421012 GO_REF:0000107 MGI:4367570 NCBI chr16:86,510,527...86,515,422
Ensembl chr16:86,510,527...86,515,422
JBrowse link
G HMOX1 heme oxygenase 1 involved_in IEA
ISO
Ensembl
RGD
PMID:17234154 GO_REF:0000107 RGD:1601626 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,207
Ensembl chr22:35,380,361...35,394,207
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 involved_in IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977
JBrowse link
G LGALS9 galectin 9 involved_in IMP (PMID:24465902) UniProt PMID:24465902 NCBI chr17:27,631,172...27,649,560
Ensembl chr17:27,629,798...27,649,560
JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 ISO (MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:3050742 NCBI chr 7:66,654,567...66,811,464
Ensembl chr 7:66,682,164...66,811,464
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A involved_in IEA
ISO
PMID:9663691 Ensembl
UniProt
PMID:9663691 GO_REF:0000107 RGD:13461752 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IDA
ISO
(PMID:23624557)
(MGI:5492190|PMID:23624557)
UniProt
UniProt
PMID:23624557 MGI:5492190 NCBI chr22:31,134,807...31,140,508
Ensembl chr22:31,134,807...31,140,508
JBrowse link
G SNX4 sorting nexin 4 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr 3:125,446,644...125,520,202
Ensembl chr 3:125,446,650...125,520,202
JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:155,881,318...155,943,769
NCBI chr  Y:57,067,838...57,130,289
Ensembl chr  X:155,881,345...155,943,769
JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in IMP (PMID:18253931) UniProt PMID:18253931 NCBI chr 2:85,577,535...85,582,031
Ensembl chr 2:85,561,562...85,582,031
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr17:15,927,782...15,975,746
Ensembl chr17:15,944,917...15,975,746
JBrowse link
G ADORA3 adenosine A3 receptor ISO (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
Ensembl chr 1:111,499,429...111,503,633
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,280...45,835,828
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:159,283,575...159,308,202
Ensembl chr 1:159,289,714...159,308,224
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 1:161,215,295...161,219,245
Ensembl chr 1:161,215,234...161,220,699
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in ISS
ISO
(MGI:5294498|PMID:21746961) UniProt
UniProt
PMID:21746961 GO_REF:0000024 MGI:5294498 NCBI chr 1:27,612,064...27,635,561
Ensembl chr 1:27,612,064...27,635,185
JBrowse link
G GAB2 GRB2 associated binding protein 2 involved_in ISS
ISO
(MGI:2137187|PMID:11449275) UniProt
UniProt
PMID:11449275 GO_REF:0000024 MGI:2137187 NCBI chr11:78,215,293...78,417,820
Ensembl chr11:78,215,293...78,418,348
JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:48,786,590...48,794,311
Ensembl chr  X:48,786,562...48,794,311
Ensembl chr  X:48,786,562...48,794,311
JBrowse link
G GATA2 GATA binding protein 2 involved_in IEA
ISO
Ensembl
RGD
PMID:22390417 GO_REF:0000107 RGD:9587812 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201
Ensembl chr 3:128,479,427...128,493,201
JBrowse link
G IL13 interleukin 13 involved_in IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110
JBrowse link
G IL4 interleukin 4 involved_in IBA
ISO
(PMID:21873635)
(MGI:3589858|PMID:15944273)
GO_Central
MGI
PMID:15944273 PMID:21873635 MGI:3589858 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678
JBrowse link
G IL4R interleukin 4 receptor involved_in IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr16:27,313,668...27,364,778
Ensembl chr16:27,313,668...27,364,778
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr11:60,088,261...60,098,467
Ensembl chr11:60,088,261...60,098,467
JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 2:231,921,809...231,926,405
Ensembl chr 2:231,921,809...231,926,396
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr17:4,807,152...4,823,432
Ensembl chr17:4,807,152...4,823,434
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in ISS
ISO
IEA
(MGI:3703830|PMID:17346996) UniProt
UniProt
Ensembl
PMID:17346996 GO_REF:0000024 GO_REF:0000107 MGI:3703830 NCBI chr19:48,619,409...48,630,407
Ensembl chr19:48,619,291...48,630,717
JBrowse link
G STXBP1 syntaxin binding protein 1 involved_in IEA
ISO
Ensembl
RGD
PMID:23487749 GO_REF:0000107 RGD:12904029 NCBI chr 9:127,611,912...127,696,029
Ensembl chr 9:127,579,370...127,696,027
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr19:7,637,110...7,647,873
Ensembl chr19:7,636,881...7,647,873
JBrowse link
G SYK spleen associated tyrosine kinase involved_in IBA
ISO
(PMID:21873635)
(MGI:85068|PMID:9000133)
GO_Central
MGI
RGD
PMID:9000133 PMID:16861349 PMID:21873635 MGI:85068 RGD:2299903 NCBI chr 9:90,801,600...90,898,549
Ensembl chr 9:90,801,787...90,898,549
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18684
    cellular process 17732
      cellular localization 3771
        regulation of cellular localization 993
          regulation of mast cell degranulation 40
            modulation of mast cell degranulation in other organism + 0
            negative regulation of mast cell degranulation 7
            positive regulation of mast cell degranulation + 24
Path 2
Term Annotations click to browse term
  biological_process 18684
    localization 7251
      establishment of localization 5648
        transport 5496
          secretion 1691
            secretion by cell 1517
              exocytosis 980
                regulated exocytosis 856
                  leukocyte degranulation 561
                    regulation of leukocyte degranulation 58
                      regulation of mast cell degranulation 40
                        modulation of mast cell degranulation in other organism + 0
                        negative regulation of mast cell degranulation 7
                        positive regulation of mast cell degranulation + 24
paths to the root