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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of mast cell degranulation
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Accession:GO:0043304 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell degranulation.
Synonyms:exact_synonym: regulation of mast cell granule exocytosis


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regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRE2 adhesion G protein-coupled receptor E2 involved_in ISO (PMID:26841242) UniProt PMID:26841242 NCBI chr20:47,929,357...47,968,525
Ensembl chr20:47,873,897...47,968,525
JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr25:26,336,253...26,357,494
Ensembl chr25:26,336,892...26,358,015
JBrowse link
G C27H12orf4 chromosome 27 C12orf4 homolog involved_in IBA
ISO
(PMID:21873635)
PMID:25122211
GO_Central
UniProt
PMID:21873635 PMID:25122211 RGD:10047193 NCBI chr27:40,341,944...40,388,424
Ensembl chr27:40,343,672...40,388,031
JBrowse link
G FER FER tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:2,863,804...3,295,999
Ensembl chr 3:2,867,726...3,295,999
JBrowse link
G FES FES proto-oncogene, tyrosine kinase involved_in IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:53,346,975...53,356,547
Ensembl chr 3:53,347,012...53,356,516
JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase involved_in IBA
ISO
IEA
(PMID:21873635)
(MGI:3703139|PMID:16272347)
GO_Central
UniProt
Ensembl
PMID:16272347 PMID:21873635 GO_REF:0000107 MGI:3703139 NCBI chr29:7,367,617...7,448,862
Ensembl chr29:7,332,684...7,448,507
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 involved_in IEA
ISO
(MGI:5298334|PMID:21063107) Ensembl
UniProt
PMID:21063107 GO_REF:0000107 MGI:5298334 NCBI chr 6:38,426,464...38,506,520
Ensembl chr 6:38,431,600...38,499,295
JBrowse link
G RAC2 Rac family small GTPase 2 involved_in IEA
ISO
(MGI:3655336|PMID:10843388) Ensembl
CACAO
PMID:10843388 GO_REF:0000107 MGI:3655336 NCBI chr10:27,295,597...27,311,864
Ensembl chr10:27,295,640...27,311,397
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chr20:52,413,174...52,421,525
Ensembl chr20:52,413,191...52,421,517
JBrowse link
G UNC13D unc-13 homolog D involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:4,753,300...4,766,751
Ensembl chr 9:4,753,166...4,766,756
JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (MGI:3721168|PMID:12874256)
(PMID:16339535)
MGI
UniProt
PMID:12874256 PMID:16339535 MGI:3721168 NCBI chr 9:5,952,428...5,976,328 JBrowse link
G CD84 CD84 molecule involved_in IEA Ensembl GO_REF:0000107 NCBI chr38:21,702,788...21,727,373
Ensembl chr38:21,702,494...21,759,668
JBrowse link
G FOXF1 forkhead box F1 involved_in IEA
ISO
(MGI:4367570|PMID:18421012) Ensembl
MGI
PMID:18421012 GO_REF:0000107 MGI:4367570 NCBI chr 5:66,343,776...66,347,785
Ensembl chr 5:66,345,150...66,347,935
JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chr10:28,744,404...28,751,544
Ensembl chr10:28,743,795...28,751,773
JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 involved_in IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:87,747,373...87,776,797
Ensembl chr  X:87,747,373...87,776,798
JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chr 9:42,154,613...42,170,423
Ensembl chr 9:42,154,702...42,170,391
JBrowse link
G RABGEF1 RAB guanine nucleotide exchange factor 1 ISO (MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:3050742 NCBI chr 6:1,064,694...1,159,906
Ensembl chr 6:1,064,655...1,179,547
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 2:84,406,317...84,408,115
Ensembl chr 2:84,396,073...84,408,385
JBrowse link
G PLA2G3 phospholipase A2 group III involved_in IEA
ISO
(MGI:5492190|PMID:23624557) Ensembl
UniProt
PMID:23624557 GO_REF:0000107 MGI:5492190 NCBI chr26:24,127,074...24,132,508
Ensembl chr26:24,128,005...24,132,508
JBrowse link
G SNX4 sorting nexin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr33:28,413,586...28,468,546
Ensembl chr33:28,419,128...28,469,488
JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:123,717,524...123,783,781
Ensembl chr  X:123,717,446...123,783,014
JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr17:39,497,628...39,501,734
Ensembl chr17:39,497,785...39,501,739
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr 5:39,884,375...39,908,214 JBrowse link
G ADORA3 adenosine A3 receptor ISO (MGI:2664591|PMID:12817016) MGI PMID:12817016 MGI:2664591 NCBI chr17:63,895,408...63,898,666
Ensembl chr17:63,895,408...63,898,666
JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr 9:9,708,696...9,763,281
Ensembl chr 9:9,714,204...9,763,402
JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr38:22,683,478...22,688,842
Ensembl chr38:22,683,477...22,690,763
JBrowse link
G FCER1G Fc fragment of IgE receptor Ig involved_in IEA
ISO
(MGI:3029067|PMID:14764707) Ensembl
MGI
PMID:14764707 GO_REF:0000107 MGI:3029067 NCBI chr38:21,267,841...21,271,036
Ensembl chr38:21,268,001...21,270,940
JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase involved_in IEA
ISO
(MGI:5294498|PMID:21746961) Ensembl
UniProt
PMID:21746961 GO_REF:0000107 MGI:5294498 NCBI chr 2:72,678,858...72,692,417
Ensembl chr 2:72,680,675...72,690,251
JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:41,991,321...41,998,319
Ensembl chr  X:41,971,582...41,998,303
JBrowse link
G GATA2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chr20:2,472,251...2,488,380
Ensembl chr20:2,473,912...2,480,991
JBrowse link
G IL13 interleukin 13 involved_in IEA
ISO
(MGI:3589858|PMID:15944273) Ensembl
MGI
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr11:20,957,870...20,961,391
Ensembl chr11:20,958,464...20,961,388
JBrowse link
G IL4 interleukin 4 involved_in IBA
ISO
(PMID:21873635)
(MGI:3589858|PMID:15944273)
GO_Central
MGI
PMID:15944273 PMID:21873635 MGI:3589858 NCBI chr11:20,972,693...20,981,539
Ensembl chr11:20,972,690...20,981,534
JBrowse link
G IL4R interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 6:19,254,183...19,280,973
Ensembl chr 6:19,254,487...19,389,291
JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr21:50,439,133...50,456,785
Ensembl chr21:50,450,024...50,456,785
JBrowse link
G NARS2 asparaginyl-tRNA synthetase 2, mitochondrial ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr21:20,277,707...20,413,624
Ensembl chr21:20,277,507...20,606,736
JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr25:43,714,545...43,718,969
Ensembl chr25:43,717,939...43,718,996
JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr 5:31,755,881...31,767,131
Ensembl chr 5:31,756,433...31,767,066
JBrowse link
G SPHK2 sphingosine kinase 2 involved_in IEA
ISO
(MGI:3703830|PMID:17346996) Ensembl
UniProt
PMID:17346996 GO_REF:0000107 MGI:3703830 NCBI chr 1:107,681,425...107,689,790
Ensembl chr 1:107,680,599...107,689,707
JBrowse link
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 9:55,690,939...55,768,008
Ensembl chr 9:55,678,264...55,727,680
JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr20:52,413,174...52,421,525
Ensembl chr20:52,413,191...52,421,517
JBrowse link
G SYK spleen associated tyrosine kinase involved_in IBA
ISO
IEA
(PMID:21873635)
(MGI:85068|PMID:9000133)
GO_Central
MGI
RGD
Ensembl
PMID:9000133 PMID:16861349 PMID:21873635 GO_REF:0000107 MGI:85068 RGD:2299903 NCBI chr 1:95,903,501...95,955,577
Ensembl chr 1:95,903,566...95,955,583
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16149
    cellular process 15475
      cellular localization 2848
        regulation of cellular localization 926
          regulation of mast cell degranulation 40
            modulation of mast cell degranulation in other organism + 0
            negative regulation of mast cell degranulation 7
            positive regulation of mast cell degranulation + 24
Path 2
Term Annotations click to browse term
  biological_process 16149
    localization 6015
      establishment of localization 4479
        transport 4317
          secretion 1075
            secretion by cell 909
              exocytosis 392
                regulated exocytosis 277
                  leukocyte degranulation 81
                    regulation of leukocyte degranulation 57
                      regulation of mast cell degranulation 40
                        modulation of mast cell degranulation in other organism + 0
                        negative regulation of mast cell degranulation 7
                        positive regulation of mast cell degranulation + 24
paths to the root