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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of mast cell degranulation
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Accession:GO:0043304 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell degranulation.
Synonyms:exact_synonym: regulation of mast cell granule exocytosis


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regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fes FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:19001085) UniProt PMID:19001085 NCBI chrNW_004955416:14,948,121...14,959,035
Ensembl chrNW_004955416:14,948,123...14,960,005
JBrowse link
G LOC102003328 chromosome unknown open reading frame, human C12orf4 ISO PMID:25122211 UniProt PMID:25122211 RGD:10047193 NCBI chrNW_004955413:2,298,514...2,335,308
Ensembl chrNW_004955413:2,298,970...2,335,237
JBrowse link
G Lyn LYN proto-oncogene, Src family tyrosine kinase ISO (MGI:3703139|PMID:16272347) UniProt PMID:16272347 MGI:3703139 NCBI chrNW_004955454:15,025,967...15,111,142
Ensembl chrNW_004955454:15,035,979...15,111,142
JBrowse link
G Pdpk1 3-phosphoinositide dependent protein kinase 1 ISO (MGI:5298334|PMID:21063107) UniProt PMID:21063107 MGI:5298334 NCBI chrNW_004955442:14,685,089...14,772,870
Ensembl chrNW_004955442:14,685,153...14,772,870
JBrowse link
G Rac2 Rac family small GTPase 2 ISO (MGI:3655336|PMID:10843388) CACAO PMID:10843388 MGI:3655336 NCBI chrNW_004955413:23,697,504...23,710,668
Ensembl chrNW_004955413:23,693,669...23,710,704
JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chrNW_004955563:1,617,621...1,624,441
Ensembl chrNW_004955563:1,617,621...1,624,441
JBrowse link
G Unc13d unc-13 homolog D involved_in ISO (PMID:15548590) UniProt PMID:15548590 NCBI chrNW_004955506:6,407,073...6,423,406
Ensembl chrNW_004955506:6,407,723...6,423,406
JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a CD300a molecule involved_in ISO (MGI:3721168|PMID:12874256)
(PMID:16339535)
MGI
UniProt
PMID:12874256 PMID:16339535 MGI:3721168 NCBI chrNW_004955553:1,335,854...1,356,001
Ensembl chrNW_004955553:1,336,227...1,460,376
JBrowse link
G Cd84 CD84 molecule involved_in ISO (PMID:22068234) UniProt PMID:22068234 NCBI chrNW_004955468:12,280,467...12,313,976
Ensembl chrNW_004955468:12,281,686...12,313,912
JBrowse link
G Foxf1 forkhead box F1 ISO (MGI:4367570|PMID:18421012) MGI PMID:18421012 MGI:4367570 NCBI chrNW_004955541:1,341,715...1,345,397
Ensembl chrNW_004955541:1,317,114...1,346,590
JBrowse link
G Hmox1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chrNW_004955405:43,124,447...43,128,873
Ensembl chrNW_004955405:43,124,510...43,130,979
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004955490:708,144...758,195
Ensembl chrNW_004955490:709,446...758,272
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chrNW_004955481:5,234,125...5,249,564 JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO (MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:3050742 NCBI chrNW_004955456:8,648,925...8,716,337
Ensembl chrNW_004955456:8,674,469...8,718,821
JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nppa natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004955486:2,061,196...2,062,805
Ensembl chrNW_004955486:2,060,735...2,063,003
JBrowse link
G Pla2g3 phospholipase A2 group III involved_in ISO (MGI:5492190|PMID:23624557)
(PMID:23624557)
UniProt PMID:23624557 MGI:5492190 NCBI chrNW_004955455:5,314,520...5,320,151
Ensembl chrNW_004955455:5,315,450...5,320,053
JBrowse link
G Snx4 sorting nexin 4 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955427:24,520,125...24,579,589
Ensembl chrNW_004955427:24,520,125...24,579,589
JBrowse link
G Vamp7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955594:20,496...72,648
Ensembl chrNW_004955594:18,727...72,654
JBrowse link
G Vamp8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chrNW_004955424:1,922,830...1,926,844
Ensembl chrNW_004955424:1,923,092...1,926,728
JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora2b adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chrNW_004955467:1,342,271...1,363,149
Ensembl chrNW_004955467:1,342,271...1,363,138
JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chrNW_004955478:10,380,185...10,390,838
Ensembl chrNW_004955478:10,379,287...10,404,825
JBrowse link
G Fcer1a Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chrNW_004955468:11,094,792...11,101,191
Ensembl chrNW_004955468:11,094,788...11,101,173
JBrowse link
G Fcer1g Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chrNW_004955468:12,971,931...12,975,206
Ensembl chrNW_004955468:12,971,931...12,975,206
JBrowse link
G Fgr FGR proto-oncogene, Src family tyrosine kinase ISO (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chrNW_004955452:6,840,274...6,863,460
Ensembl chrNW_004955452:6,841,802...6,863,542
JBrowse link
G Gab2 GRB2 associated binding protein 2 ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chrNW_004955414:13,640,713...13,754,401
Ensembl chrNW_004955414:13,679,588...13,751,079
JBrowse link
G Gata1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004955543:334,581...342,042
Ensembl chrNW_004955543:334,061...342,061
JBrowse link
G Gata2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chrNW_004955429:15,326,551...15,334,774
Ensembl chrNW_004955429:15,327,113...15,336,460
JBrowse link
G Il13 interleukin 13 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004955408:4,046,406...4,049,795 JBrowse link
G Il4 interleukin 4 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004955408:4,058,052...4,065,999 JBrowse link
G Il4r interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chrNW_004955493:5,546,340...5,580,745
Ensembl chrNW_004955493:5,545,944...5,582,422
JBrowse link
G Ms4a2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chrNW_004955511:4,377,894...4,400,797
Ensembl chrNW_004955511:4,380,502...4,400,852
JBrowse link
G Nppc natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chrNW_004955453:3,884,580...3,888,494
Ensembl chrNW_004955453:3,884,560...3,888,850
JBrowse link
G Pld2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chrNW_004955467:10,239,177...10,250,516
Ensembl chrNW_004955467:10,239,177...10,250,890
JBrowse link
G Sphk2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chrNW_004955559:1,921,479...1,929,450
Ensembl chrNW_004955559:1,917,301...1,928,493
JBrowse link
G Stxbp1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004955419:963,829...1,000,759
Ensembl chrNW_004955419:963,829...1,000,759
JBrowse link
G Stxbp2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chrNW_004955563:1,617,621...1,624,441
Ensembl chrNW_004955563:1,617,621...1,624,441
JBrowse link
G Syk spleen associated tyrosine kinase ISO (MGI:85068|PMID:9000133) RGD
MGI
PMID:9000133 PMID:16861349 MGI:85068 RGD:2299903 NCBI chrNW_004955515:1,328,793...1,400,206
Ensembl chrNW_004955515:1,328,630...1,380,581
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 11940
    cellular process 11157
      cellular localization 2352
        regulation of cellular localization 878
          regulation of mast cell degranulation 36
            modulation of mast cell degranulation in other organism + 0
            negative regulation of mast cell degranulation 7
            positive regulation of mast cell degranulation + 23
Path 2
Term Annotations click to browse term
  biological_process 11940
    localization 4785
      establishment of localization 3423
        transport 3263
          secretion 953
            secretion by cell 808
              exocytosis 317
                regulated exocytosis 244
                  leukocyte degranulation 70
                    regulation of leukocyte degranulation 49
                      regulation of mast cell degranulation 36
                        modulation of mast cell degranulation in other organism + 0
                        negative regulation of mast cell degranulation 7
                        positive regulation of mast cell degranulation + 23
paths to the root