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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of mast cell degranulation
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Accession:GO:0043304 term browser browse the term
Definition:Any process that modulates the frequency, rate, or extent of mast cell degranulation.
Synonyms:exact_synonym: regulation of mast cell granule exocytosis

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regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADGRE2 adhesion G protein-coupled receptor E2 involved_in ISO (PMID:26841242) UniProt PMID:26841242 NCBI chr19:14,259,830...14,331,832
Ensembl chr19:15,148,143...15,186,458 		JBrowse link
G C12H12orf4 chromosome 12 C12orf4 homolog ISO PMID:25122211 UniProt PMID:25122211 RGD:10047193 NCBI chr12:4,597,513...4,657,700
Ensembl chr12:4,520,082...4,578,361 		JBrowse link
G FES FES proto-oncogene, tyrosine kinase involved_in ISO (PMID:19001085) UniProt PMID:19001085 NCBI chr15:69,576,936...69,588,834
Ensembl chr15:88,774,965...88,786,965 		JBrowse link
G LYN LYN proto-oncogene, Src family tyrosine kinase ISO (MGI:3703139|PMID:16272347) UniProt PMID:16272347 MGI:3703139 NCBI chr 8:52,318,497...52,455,741
Ensembl chr 8:49,755,708...49,825,287 		JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO (MGI:5298334|PMID:21063107) UniProt PMID:21063107 MGI:5298334 NCBI chr16:1,394,447...1,463,735 JBrowse link
G RAC2 Rac family small GTPase 2 ISO (MGI:3655336|PMID:10843388) CACAO PMID:10843388 MGI:3655336 NCBI chr22:18,138,517...18,159,023
Ensembl chr22:35,973,229...35,992,026 		JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:12482918 RGD:2312429 NCBI chr19:6,926,833...6,937,385
Ensembl chr19:7,781,830...7,792,038 		JBrowse link
G UNC13D unc-13 homolog D involved_in ISO (PMID:15548590) UniProt PMID:15548590 NCBI chr17:69,777,570...69,794,877
Ensembl chr17:75,328,572...75,344,842 		JBrowse link
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CD300A CD300a molecule involved_in ISO (MGI:3721168|PMID:12874256)
(PMID:16339535)		 MGI
UniProt		 PMID:12874256 PMID:16339535 MGI:3721168 NCBI chr17:68,403,647...68,426,285
Ensembl chr17:73,965,008...73,983,928 		JBrowse link
G CD84 CD84 molecule involved_in ISO (PMID:22068234) UniProt PMID:22068234 NCBI chr 1:135,901,375...135,934,791
Ensembl chr 1:139,819,254...139,857,559 		JBrowse link
G FOXF1 forkhead box F1 ISO (MGI:4367570|PMID:18421012) MGI PMID:18421012 MGI:4367570 NCBI chr16:67,183,416...67,188,211
Ensembl chr16:86,516,119...86,519,949 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:17234154 RGD:1601626 NCBI chr22:16,388,368...16,401,289
Ensembl chr22:34,230,825...34,244,063 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr  X:104,092,993...104,146,062
Ensembl chr  X:114,597,077...114,635,253 		JBrowse link
G LGALS9 galectin 9 involved_in ISO (PMID:24465902) UniProt PMID:24465902 NCBI chr17:29,125,460...29,145,028
Ensembl chr17:29,623,398...29,642,959 		JBrowse link
G LOC100993573 rab5 GDP/GTP exchange factor ISO (MGI:3050742|PMID:15235600) MGI PMID:15235600 MGI:3050742 NCBI chr 7:59,268,053...59,344,555
Ensembl chr 7:73,775,002...73,850,446 		JBrowse link
positive regulation of histamine secretion by mast cell term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NPPA natriuretic peptide A ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr 1:10,608,025...10,610,287
Ensembl chr 1:11,825,072...11,827,373 		JBrowse link
G PLA2G3 phospholipase A2 group III involved_in ISO (MGI:5492190|PMID:23624557)
(PMID:23624557)		 UniProt PMID:23624557 MGI:5492190 NCBI chr22:12,158,589...12,164,441
Ensembl chr22:29,995,364...30,001,160 		JBrowse link
G SNX4 sorting nexin 4 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr 3:122,578,527...122,652,007
Ensembl chr 3:129,443,369...129,515,917 		JBrowse link
G VAMP7 vesicle associated membrane protein 7 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr  X:145,362,432...145,425,097
Ensembl chr  X:155,257,185...155,320,215 		JBrowse link
G VAMP8 vesicle associated membrane protein 8 involved_in ISO (PMID:18253931) UniProt PMID:18253931 NCBI chr2A:85,627,678...85,632,205
Ensembl chr2A:87,180,681...87,185,195 		JBrowse link
positive regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADORA2B adenosine A2b receptor ISO (MGI:3776334|PMID:11454903) MGI PMID:11454903 MGI:3776334 NCBI chr17:34,849,466...34,880,088 JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO RGD PMID:18209484 RGD:5130941 NCBI chr17:11,261,435...11,313,630
Ensembl chr17:11,650,057...11,701,208 		JBrowse link
G FCER1A Fc fragment of IgE receptor Ia ISO (MGI:85068|PMID:9000133) MGI PMID:9000133 MGI:85068 NCBI chr 1:134,655,230...134,660,961
Ensembl chr 1:138,439,921...138,458,258 		JBrowse link
G FCER1G Fc fragment of IgE receptor Ig ISO (MGI:3029067|PMID:14764707) MGI PMID:14764707 MGI:3029067 NCBI chr 1:136,627,672...136,631,696
Ensembl chr 1:140,539,555...140,544,810 		JBrowse link
G FGR FGR proto-oncogene, Src family tyrosine kinase ISO (MGI:5294498|PMID:21746961) UniProt PMID:21746961 MGI:5294498 NCBI chr 1:26,872,781...26,895,751
Ensembl chr 1:27,918,758...27,941,678 		JBrowse link
G GAB2 GRB2 associated binding protein 2 ISO (MGI:2137187|PMID:11449275) UniProt PMID:11449275 MGI:2137187 NCBI chr11:73,275,360...73,478,272
Ensembl chr11:76,896,691...76,967,007 		JBrowse link
G GATA1 GATA binding protein 1 ISO RGD PMID:22390417 RGD:9587812 NCBI chr  X:41,088,724...41,092,190
Ensembl chr  X:48,945,394...48,953,126 		JBrowse link
G GATA2 GATA binding protein 2 ISO RGD PMID:22390417 RGD:9587812 NCBI chr 3:125,526,537...125,535,649
Ensembl chr 3:132,890,508...132,899,035 		JBrowse link
G IL13 interleukin 13 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 5:128,073,863...128,078,453
Ensembl chr 5:134,235,788...134,240,548 		JBrowse link
G IL4 interleukin 4 ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 NCBI chr 5:128,091,342...128,099,886
Ensembl chr 5:134,253,039...134,261,581 		JBrowse link
G IL4R interleukin 4 receptor ISO (MGI:3589858|PMID:15944273) MGI PMID:15944273 MGI:3589858 Ensembl chr16:27,642,702...27,737,445 JBrowse link
G MS4A2 membrane spanning 4-domains A2 ISO RGD PMID:16177098 RGD:1578516 NCBI chr11:55,318,843...55,326,779
Ensembl chr11:58,764,911...58,772,567 		JBrowse link
G NPPC natriuretic peptide C ISO PMID:9663691 UniProt PMID:9663691 RGD:13461752 NCBI chr2B:119,148,774...119,153,381
Ensembl chr2B:237,936,939...237,941,244 		JBrowse link
G PLD2 phospholipase D2 ISO RGD PMID:16861349 RGD:2299903 NCBI chr17:4,853,919...4,870,254
Ensembl chr17:4,843,217...4,858,425 		JBrowse link
G SPHK2 sphingosine kinase 2 ISO (MGI:3703830|PMID:17346996) UniProt PMID:17346996 MGI:3703830 NCBI chr19:45,620,980...45,631,786
Ensembl chr19:54,213,166...54,224,767 		JBrowse link
G STXBP1 syntaxin binding protein 1 ISO RGD PMID:23487749 RGD:12904029 NCBI chr 9:98,731,527...98,811,608
Ensembl chr 9:127,434,080...127,486,152 		JBrowse link
G STXBP2 syntaxin binding protein 2 ISO RGD PMID:23487749 RGD:12904029 NCBI chr19:6,926,833...6,937,385
Ensembl chr19:7,781,830...7,792,038 		JBrowse link
G SYK spleen associated tyrosine kinase ISO (MGI:85068|PMID:9000133) RGD
MGI		 PMID:9000133 PMID:16861349 MGI:85068 RGD:2299903 NCBI chr 9:61,859,767...61,956,619
Ensembl chr 9:89,959,599...90,056,101 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12617
    cellular process 11733
      cellular localization 2397
        regulation of cellular localization 895
          regulation of mast cell degranulation 37
            modulation of mast cell degranulation in other organism + 0
            negative regulation of mast cell degranulation 7
            positive regulation of mast cell degranulation + 23
Path 2
Term Annotations click to browse term
  biological_process 12617
    localization 4966
      establishment of localization 3545
        transport 3381
          secretion 988
            secretion by cell 832
              exocytosis 327
                regulated exocytosis 249
                  leukocyte degranulation 73
                    regulation of leukocyte degranulation 51
                      regulation of mast cell degranulation 37
                        modulation of mast cell degranulation in other organism + 0
                        negative regulation of mast cell degranulation 7
                        positive regulation of mast cell degranulation + 23
paths to the root