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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of leukocyte degranulation
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Accession:GO:0043301 term browser browse the term
Definition:Any process that stops, prevents, or reduces the rate of leukocyte degranulation.
Synonyms:exact_synonym: down regulation of leukocyte degranulation;   downregulation of leukocyte degranulation;   negative regulation of immune cell degranulation;   negative regulation of leucocyte degranulation
 narrow_synonym: inhibition of leukocyte degranulation


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negative regulation of cytotoxic T cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ceacam1 CEA cell adhesion molecule 1 involved_in ISO
ISS
(PMID:18424730)
GO_REF:0000024
RGD
UniProt
PMID:18424730 GO_REF:0000024 NCBI chr 1:82,327,955...82,344,345
Ensembl chr 1:82,327,955...82,344,345
JBrowse link
negative regulation of eosinophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ccr2 C-C motif chemokine receptor 2 involved_in ISS
ISO
GO_REF:0000024
(MGI:3699670|PMID:14662900)
BHF-UCL
RGD
PMID:14662900 GO_REF:0000024 MGI:3699670
negative regulation of mast cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cd300a Cd300a molecule involved_in ISO (PMID:16339535)
(MGI:3721168|PMID:12874256)
RGD PMID:12874256 PMID:16339535 MGI:3721168 NCBI chr10:103,437,978...103,451,170
Ensembl chr10:103,438,303...103,450,947
JBrowse link
G Cd84 CD84 molecule involved_in ISO (PMID:22068234) RGD PMID:22068234 NCBI chr13:90,241,369...90,283,625
Ensembl chr13:90,244,681...90,277,865
JBrowse link
G Foxf1 forkhead box F1 ISO MGI:2179135 (MGI:4367570|PMID:18421012) RGD PMID:18421012 MGI:4367570 NCBI chr19:53,012,306...53,016,100
Ensembl chr19:53,012,332...53,016,086
JBrowse link
G Hmox1 heme oxygenase 1 IDA RGD PMID:17234154 RGD:1601626 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Il13ra2 interleukin 13 receptor subunit alpha 2 IEA
ISO
GO_REF:0000107
MGI:2653910 (MGI:3589858|PMID:15944273)
Ensembl
RGD
PMID:15944273 GO_REF:0000107 MGI:3589858 NCBI chr  X:118,443,955...118,514,716
Ensembl chr  X:118,443,823...118,513,061
JBrowse link
G Lgals9 galectin 9 involved_in ISO (PMID:24465902) RGD PMID:24465902 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G Rabgef1 RAB guanine nucleotide exchange factor 1 ISO MGI:3051384 (MGI:3050742|PMID:15235600) RGD PMID:15235600 MGI:3050742 NCBI chr12:29,960,132...30,004,727
Ensembl chr12:29,961,120...29,988,959
JBrowse link
negative regulation of natural killer cell degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lgals9 galectin 9 ISO (MGI:5491117|PMID:23408620) RGD PMID:23408620 MGI:5491117 NCBI chr10:64,737,022...64,760,195
Ensembl chr10:64,737,022...64,760,201
JBrowse link
G RT1-CE5 RT1 class I, locus CE5 involved_in ISO (PMID:24018270) RGD PMID:24018270 NCBI chr20:4,892,702...4,896,993
Ensembl chr20:4,892,702...4,896,991
JBrowse link
negative regulation of neutrophil degranulation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abr ABR activator of RhoGEF and GTPase ISO MGI:88141 (MGI:4366690|PMID:19703997) RGD PMID:19703997 MGI:4366690 NCBI chr10:64,565,121...64,657,079
Ensembl chr10:64,567,268...64,657,089
JBrowse link
G Bcr BCR activator of RhoGEF and GTPase ISO MGI:107771 (MGI:4366690|PMID:19703997) RGD PMID:19703997 MGI:4366690 NCBI chr20:14,421,250...14,546,406
Ensembl chr20:14,421,141...14,545,772
JBrowse link
G Spi1 Spi-1 proto-oncogene involved_in IEA GO_REF:0000107 Ensembl GO_REF:0000107 NCBI chr 3:79,918,127...79,937,708
Ensembl chr 3:79,918,969...79,938,301
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20078
    immune system process 2843
      immune effector process 902
        negative regulation of immune effector process 145
          negative regulation of leukocyte degranulation 13
            negative regulation of basophil degranulation 0
            negative regulation of cytotoxic T cell degranulation 1
            negative regulation of eosinophil degranulation 1
            negative regulation of mast cell degranulation 7
            negative regulation of natural killer cell degranulation 2
            negative regulation of neutrophil degranulation 3
Path 2
Term Annotations click to browse term
  biological_process 20078
    localization 6501
      establishment of localization 4917
        transport 4753
          secretion 1167
            secretion by cell 966
              exocytosis 431
                regulated exocytosis 296
                  leukocyte degranulation 92
                    regulation of leukocyte degranulation 62
                      negative regulation of leukocyte degranulation 13
                        negative regulation of basophil degranulation 0
                        negative regulation of cytotoxic T cell degranulation 1
                        negative regulation of eosinophil degranulation 1
                        negative regulation of mast cell degranulation 7
                        negative regulation of natural killer cell degranulation 2
                        negative regulation of neutrophil degranulation 3
paths to the root