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Accession:GO:0043293 term browser browse the term
Definition:A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
Synonyms:xref: Wikipedia:Apoptosome
 never_in_taxon: NCBITaxon:4890 ! Ascomycota

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apoptosome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Apaf1 apoptotic peptidase activating factor 1 part_of ISO PMID:26265044
PMID:17483091 PMID:21827945 PMID:26265044 RGD:11079191 RGD:2325744 NCBI chrNW_004936492:14,818,561...14,902,231 JBrowse link
G Casp9 caspase 9 part_of ISO (PMID:21827945) UniProt PMID:21827945 NCBI chrNW_004936474:3,178,097...3,196,130 JBrowse link
G Uaca uveal autoantigen with coiled-coil domains and ankyrin repeats part_of ISO (MGI:3056865|PMID:15271982) MGI PMID:15271982 MGI:3056865 NCBI chrNW_004936471:30,213,742...30,312,873 JBrowse link

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  cellular_component 12285
    protein-containing complex 3915
      apoptosome 3
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  cellular_component 12285
    cellular anatomical entity 12141
      intracellular anatomical structure 10410
        cytoplasm 8093
          cytosol 3001
            apoptosome 3
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